AutismKB 2.0

Annotation Detail for NRCAM


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Basic Information Top
Gene Symbol:NRCAM ( KIAA0343,MGC138845,MGC138846 )
Gene Full Name: neuronal cell adhesion molecule
Band: 7q31.1
Quick LinksEntrez ID:4897; OMIM: 601581; Uniprot ID:NRCAM_HUMAN; ENSEMBL ID: ENSG00000091129; HGNC ID: 7994
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus30 / 56401253
neonate2 / 3109764
infant1 / 2362042
juvenile3 / 5555653
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma18 / 106883168
head and neck tumor0 / 1363020 
kidney tumor10 / 68959145
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal204 / 336030760
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain162 / 1100989147
cervix0 / 481710 
connective tissue1 / 1492556
ear2 / 16212123
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye13 / 21105461
heart2 / 8962622
intestine2 / 2344728
kidney15 / 21177770
larynx0 / 241450 
liver1 / 2077434
lung14 / 33697441
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle7 / 10771564
nerve3 / 15768190
ovary3 / 10205129
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis11 / 33044233
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus1 / 2328784
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216959_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.3
Adipocyte5.25
AdrenalCortex4.6
Adrenalgland3.7
Amygdala5.65
Appendix4.45
AtrioventricularNode4.85
BDCA4+_DentriticCells4.7
Bonemarrow4.4
BronchialEpithelialCells4.25
CD105+_Endothelial4.45
CD14+_Monocytes4.55
CD19+_BCells(neg._sel.)4.6
CD33+_Myeloid5.65
CD34+5.55
CD4+_Tcells4.85
CD56+_NKCells5.1
CD71+_EarlyErythroid4.1
CD8+_Tcells4.2
CardiacMyocytes5.65
Caudatenucleus3.95
Cerebellum3.55
CerebellumPeduncles5.5
CiliaryGanglion3.15
CingulateCortex4.5
Colorectaladenocarcinoma4.35
DorsalRootGanglion3.75
FetalThyroid4.2
Fetalbrain5
Fetalliver3.8
Fetallung3.65
GlobusPallidus4.7
Heart5.6
Hypothalamus5.15
Kidney3.55
Leukemia_chronicMyelogenousK-5624
Leukemia_promyelocytic-HL-603.9
Leukemialymphoblastic(MOLT-4)3.55
Liver5.8
Lung4.8
Lymphnode3.75
Lymphoma_burkitts(Daudi)5.55
Lymphoma_burkitts(Raji)6.15
MedullaOblongata4.7
OccipitalLobe8.55
OlfactoryBulb3.45
Ovary2.9
Pancreas3.5
PancreaticIslet4.65
ParietalLobe5.6
Pituitary5.15
Placenta4.5
Pons4.95
PrefrontalCortex6.55
Prostate5.15
Salivarygland3.5
SkeletalMuscle5.05
Skin3.45
SmoothMuscle4.9
Spinalcord5.75
SubthalamicNucleus8
SuperiorCervicalGanglion5.5
TemporalLobe4.75
Testis3.7
TestisGermCell3.7
TestisIntersitial3.75
TestisLeydigCell4.35
TestisSeminiferousTubule3.75
Thalamus4.6
Thymus3.45
Thyroid5.45
Tongue4.3
Tonsil4.25
Trachea3.7
TrigeminalGanglion4.45
Uterus3.65
UterusCorpus3.9
WholeBlood4.75
Wholebrain3.85
colon4.35
pineal_day5.48
pineal_night5.36
retina5.275
small_intestine4.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_483_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.32 ± 0.28
Basal Forebrain8.83 ± 0.2
Basal Part of Pons9.39 ± 0.33
Cerebellar Cortex8.8 ± 0.28
Cerebellar Nuclei8.49 ± 0.33
Claustrum9.72 ± 0.23
Epithalamus8.23 ± 0.59
Frontal Lobe9.19 ± 0.51
Globus Pallidus8.46 ± 0.45
Hypothalamus8.56 ± 0.6
Insula9.17 ± 0.29
Limbic Lobe9.21 ± 0.41
Mesencephalon8.95 ± 0.51
Myelencephalon9.02 ± 0.56
Occipital Lobe8.95 ± 0.44
Parietal Lobe9.26 ± 0.5
Pontine Tegmentum8.93 ± 0.41
Striatum8.28 ± 0.65
Subthalamus8.64 ± 0.1
Temporal Lobe9.24 ± 0.35
Thalamus9.3 ± 0.39
White Matter7.75 ± 0.61
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
C130076O07RikCBCerebellum24.49
33.11
C130076O07RikCTXCerebral cortex96.29
92.38
C130076O07RikHIPHippocampal region71.1
100
C130076O07RikHPFHippocampal formation82.36
100
C130076O07RikHYHypothalamus13.61
11.08
C130076O07RikLSXLateral septal complex13.61
11.55
C130076O07RikMBMidbrain12.67
12.43
C130076O07RikMYMedulla21.8
32.9
C130076O07RikOLFOlfactory bulb92.2
80.69
C130076O07RikPPons16.66
19.67
C130076O07RikPALPallidum13.52
13.19
C130076O07RikRHPRetrohippocampal region97.6
94.03
C130076O07RiksAMYStriatum-like amygdalar nuclei50.82
45.75
C130076O07RikSTRStriatum22.49
21.12
C130076O07RikSTRdStriatum dorsal region17.95
18.29
C130076O07RikSTRvStriatum ventral region28.18
21.61
C130076O07RikTHThalamus23.98
23.17
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00136382 15 405 419 KIDGDTIIFSNVQER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018