AutismKB 2.0

Annotation Detail for YBX1


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Basic Information Top
Gene Symbol:YBX1 ( BP-8,CSDA2,CSDB,DBPB,MDR-NF1,MGC104858,MGC110976,MGC117250,NSEP-1,NSEP1,YB-1,YB1 )
Gene Full Name: Y box binding protein 1
Band: 1p34.2
Quick LinksEntrez ID:4904; OMIM: 154030; Uniprot ID:YBOX1_HUMAN; ENSEMBL ID: ENSG00000065978; HGNC ID: 8014
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body58 / 70761819
blastocyst77 / 623191235
fetus168 / 564012297
neonate0 / 310970 
infant2 / 2362084
juvenile70 / 555561259
adult708 / 1939121365
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma3 / 17475171
breast (mammary gland) tumor56 / 94178594
cervical tumor30 / 34366872
chondrosarcoma53 / 82823639
colorectal tumor22 / 114246192
esophageal tumor2 / 17290115
gastrointestinal tumor112 / 119369938
germ cell tumor87 / 263845329
glioma29 / 106883271
head and neck tumor30 / 136302220
kidney tumor35 / 68959507
leukemia63 / 95842657
liver tumor35 / 96359363
lung tumor45 / 103127436
lymphoma76 / 717551059
non-neoplasia12 / 97250123
normal1017 / 3360307302
ovarian tumor26 / 76682339
pancreatic tumor59 / 104616563
primitive neuroectodermal tumor of the CNS53 / 125680421
prostate cancer44 / 102680428
retinoblastoma100 / 463562157
skin tumor90 / 124949720
soft tissue/muscle tissue tumor151 / 1251911206
uterine tumor57 / 90257631
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland8 / 33197240
ascites27 / 40015674
bladder5 / 29757168
blood73 / 123478591
bone57 / 71655795
bone marrow7 / 48801143
brain202 / 1100989183
cervix35 / 48171726
connective tissue41 / 149255274
ear5 / 16212308
embryonic tissue231 / 2157221070
esophagus2 / 2020998
eye158 / 211054748
heart22 / 89626245
intestine52 / 234472221
kidney42 / 211777198
larynx5 / 24145207
liver68 / 207743327
lung126 / 336974373
lymph58 / 442701310
lymph node34 / 91610371
mammary gland57 / 153271371
mouth1 / 6705214
muscle43 / 107715399
nerve8 / 15768507
ovary30 / 102051293
pancreas97 / 214812451
parathyroid0 / 205390 
pharynx8 / 41328193
pituitary gland1 / 1658560
placenta84 / 280825299
prostate49 / 189345258
salivary gland10 / 20155496
skin111 / 210574527
spleen4 / 5395274
stomach74 / 96619765
testis51 / 330442154
thymus3 / 8113136
thyroid8 / 47473168
tonsil1 / 1699958
trachea3 / 5241357
umbilical cord0 / 136800 
uterus177 / 232878760
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208627_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4498.5
Adipocyte1419.55
AdrenalCortex157.7
Adrenalgland286
Amygdala279.4
Appendix393.55
AtrioventricularNode213.5
BDCA4+_DentriticCells2285.55
Bonemarrow766.05
BronchialEpithelialCells2390.8
CD105+_Endothelial2426.15
CD14+_Monocytes1622.85
CD19+_BCells(neg._sel.)1800.6
CD33+_Myeloid1417.35
CD34+2121.7
CD4+_Tcells1922.35
CD56+_NKCells1282.75
CD71+_EarlyErythroid3974.6
CD8+_Tcells1511.4
CardiacMyocytes2093.7
Caudatenucleus160
Cerebellum262.1
CerebellumPeduncles394.05
CiliaryGanglion131.95
CingulateCortex68.65
Colorectaladenocarcinoma1627.55
DorsalRootGanglion252.35
FetalThyroid580.6
Fetalbrain3168.4
Fetalliver1154.65
Fetallung853.95
GlobusPallidus51.45
Heart990.45
Hypothalamus196.4
Kidney289.8
Leukemia_chronicMyelogenousK-5621884.05
Leukemia_promyelocytic-HL-601985.5
Leukemialymphoblastic(MOLT-4)2209.85
Liver416.05
Lung1271.35
Lymphnode615.85
Lymphoma_burkitts(Daudi)2605.55
Lymphoma_burkitts(Raji)2032.1
MedullaOblongata80.95
OccipitalLobe184
OlfactoryBulb464.4
Ovary434.45
Pancreas446.4
PancreaticIslet426.2
ParietalLobe138.8
Pituitary223.15
Placenta608.7
Pons76.4
PrefrontalCortex112.25
Prostate960.9
Salivarygland364.05
SkeletalMuscle710.5
Skin198.8
SmoothMuscle2372.75
Spinalcord273.4
SubthalamicNucleus77.4
SuperiorCervicalGanglion90.45
TemporalLobe93.8
Testis2321.1
TestisGermCell5086.65
TestisIntersitial4890.05
TestisLeydigCell4283.1
TestisSeminiferousTubule3182.15
Thalamus184.7
Thymus1004.95
Thyroid1225.4
Tongue373.65
Tonsil870.25
Trachea464.25
TrigeminalGanglion72.3
Uterus929.65
UterusCorpus544.75
WholeBlood684.65
Wholebrain214.3
colon1151.7
pineal_day940.9
pineal_night784.92
retina988.025
small_intestine856.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P169754
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.05 ± 0.23
Basal Forebrain8.35 ± 0.18
Basal Part of Pons8.11 ± 0.26
Cerebellar Cortex8.28 ± 0.19
Cerebellar Nuclei8.22 ± 0.37
Claustrum7.93 ± 0.32
Epithalamus8.44 ± 0.46
Frontal Lobe8.03 ± 0.31
Globus Pallidus8.83 ± 0.39
Hypothalamus7.81 ± 0.5
Insula8.08 ± 0.24
Limbic Lobe8.1 ± 0.3
Mesencephalon8.08 ± 0.43
Myelencephalon8.1 ± 0.38
Occipital Lobe8.23 ± 0.33
Parietal Lobe7.99 ± 0.35
Pontine Tegmentum8.12 ± 0.25
Striatum8.39 ± 0.42
Subthalamus7.91 ± 0.34
Temporal Lobe7.98 ± 0.25
Thalamus8.14 ± 0.29
White Matter9.01 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ybx1CBCerebellum28.18
17.91
Ybx1CTXCerebral cortex40.96
29.21
Ybx1HIPHippocampal region49.6
61.93
Ybx1HPFHippocampal formation45.34
49.33
Ybx1HYHypothalamus15.76
10.65
Ybx1LSXLateral septal complex17.38
12.03
Ybx1MBMidbrain10.71
8.47
Ybx1MYMedulla19.72
17.57
Ybx1OLFOlfactory bulb68.77
50.91
Ybx1PPons13.29
12.57
Ybx1PALPallidum12.33
9.75
Ybx1RHPRetrohippocampal region38.98
33.5
Ybx1sAMYStriatum-like amygdalar nuclei26.28
16.69
Ybx1STRStriatum32.64
21.02
Ybx1STRdStriatum dorsal region32.3
20.77
Ybx1STRvStriatum ventral region43.66
26.57
Ybx1THThalamus31.28
23.36
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005741 16 78 93 NDTKEDVFVHQTAIKK Peptide Atlas
YBOX1_HUMAN_101 17 101 117 SVGDGETVEFDVVEGEK PRIDE
YBOX1_HUMAN_118 19 118 136 GAEAANVTGPGGVPVQGSK PRIDE
YBOX1_HUMAN_192 8 192 199 RFPPYYMR PRIDE
YBOX1_HUMAN_193 7 193 199 FPPYYMR PRIDE
YBOX1_HUMAN_204 30 204 233 RPQYSNPPVQGEVMEGADNQGAGEQGRPVR PRIDE
YBOX1_HUMAN_256 23 256 278 EDGNEEDKENQGDETQGQQPPQR PRIDE
YBOX1_HUMAN_257 23 257 279 EDGNEEDKENQGDETQGQQPPQR PRIDE
YBOX1_HUMAN_259 22 259 280 GNEEDKENQGDETQGQQPPQRR PRIDE
YBOX1_HUMAN_304 20 304 323 AADPPAENSSAPEAEQGGAE PRIDE
YBOX1_HUMAN_308 17 308 324 PPAENSSAPEAEQGGAE PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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