AutismKB 2.0

Annotation Detail for NTF3


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Basic Information Top
Gene Symbol:NTF3 ( HDNF,MGC129711,NGF-2,NGF2,NT3 )
Gene Full Name: neurotrophin 3
Band: 12p13.31
Quick LinksEntrez ID:4908; OMIM: 162660; Uniprot ID:NTF3_HUMAN; ENSEMBL ID: ENSG00000185652; HGNC ID: 8023
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal12 / 33603073
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206706_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.7
Adipocyte7.45
AdrenalCortex10.25
Adrenalgland6.5
Amygdala8.25
Appendix10.85
AtrioventricularNode6.85
BDCA4+_DentriticCells7.5
Bonemarrow7.85
BronchialEpithelialCells7.65
CD105+_Endothelial7.85
CD14+_Monocytes8.3
CD19+_BCells(neg._sel.)7.3
CD33+_Myeloid9.1
CD34+8.95
CD4+_Tcells8.3
CD56+_NKCells8.95
CD71+_EarlyErythroid7
CD8+_Tcells7.3
CardiacMyocytes10.3
Caudatenucleus6.95
Cerebellum6.25
CerebellumPeduncles10.25
CiliaryGanglion5.35
CingulateCortex9.4
Colorectaladenocarcinoma7.7
DorsalRootGanglion6
FetalThyroid7.9
Fetalbrain7.75
Fetalliver6.65
Fetallung6.5
GlobusPallidus5.7
Heart10.1
Hypothalamus8.25
Kidney6.25
Leukemia_chronicMyelogenousK-5626.9
Leukemia_promyelocytic-HL-606.75
Leukemialymphoblastic(MOLT-4)5.9
Liver10.85
Lung8.65
Lymphnode6.7
Lymphoma_burkitts(Daudi)10
Lymphoma_burkitts(Raji)11.4
MedullaOblongata7.15
OccipitalLobe7
OlfactoryBulb6.15
Ovary5.4
Pancreas6.2
PancreaticIslet8.15
ParietalLobe8.2
Pituitary9.05
Placenta8
Pons9.7
PrefrontalCortex9.75
Prostate9.1
Salivarygland6.15
SkeletalMuscle12.3
Skin5.85
SmoothMuscle8.6
Spinalcord8.25
SubthalamicNucleus7
SuperiorCervicalGanglion14.1
TemporalLobe7.05
Testis6.7
TestisGermCell6.65
TestisIntersitial7
TestisLeydigCell8.15
TestisSeminiferousTubule6.65
Thalamus7.85
Thymus6.1
Thyroid9.65
Tongue7.6
Tonsil7.6
Trachea6.45
TrigeminalGanglion9.65
Uterus6.4
UterusCorpus9.4
WholeBlood8.45
Wholebrain6.7
colon7.75
pineal_day88.74
pineal_night125.34
retina9.675
small_intestine7.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P360797
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.73 ± 0.74
Basal Forebrain1.97 ± 0.28
Basal Part of Pons2.11 ± 0.59
Cerebellar Cortex4.04 ± 0.91
Cerebellar Nuclei2.78 ± 0.66
Claustrum4.16 ± 1.2
Epithalamus2.36 ± 0.96
Frontal Lobe2.67 ± 1.09
Globus Pallidus2.36 ± 0.99
Hypothalamus2.51 ± 0.95
Insula2.97 ± 0.65
Limbic Lobe3.09 ± 1.33
Mesencephalon2.72 ± 0.88
Myelencephalon2.7 ± 0.76
Occipital Lobe2.62 ± 1.42
Parietal Lobe2.77 ± 1.1
Pontine Tegmentum2.83 ± 1.17
Striatum2.1 ± 0.73
Subthalamus2.51 ± 0.8
Temporal Lobe2.68 ± 1.02
Thalamus2.53 ± 0.83
White Matter1.75 ± 0.75
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ntf3CBCerebellum10.42
6.26
Ntf3CTXCerebral cortex3.89
2.38
Ntf3HIPHippocampal region20.17
10.94
Ntf3HPFHippocampal formation18.36
9.35
Ntf3HYHypothalamus1.36
0.63
Ntf3LSXLateral septal complex4.43
6.18
Ntf3MBMidbrain2.77
2.08
Ntf3MYMedulla2.25
1.41
Ntf3OLFOlfactory bulb10.23
6.31
Ntf3PPons1.54
1.27
Ntf3PALPallidum0.24
0.31
Ntf3RHPRetrohippocampal region15.56
7.33
Ntf3sAMYStriatum-like amygdalar nuclei0.71
0.59
Ntf3STRStriatum0.88
0.82
Ntf3STRdStriatum dorsal region0.71
0.5
Ntf3STRvStriatum ventral region0.29
0.15
Ntf3THThalamus2.8
1.21
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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