AutismKB 2.0

Annotation Detail for ATP2B2


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Basic Information Top
Gene Symbol:ATP2B2 ( PMCA2,PMCA2a,PMCA2i )
Gene Full Name: ATPase, Ca++ transporting, plasma membrane 2
Band: 3p25.3
Quick LinksEntrez ID:491; OMIM: 108733; Uniprot ID:AT2B2_HUMAN; ENSEMBL ID: ENSG00000157087; HGNC ID: 815
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus26 / 56401246
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma7 / 10688365
head and neck tumor5 / 13630236
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal127 / 336030737
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain96 / 110098987
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine1 / 2344724
kidney4 / 21177718
larynx3 / 24145124
liver7 / 20774333
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle3 / 10771527
nerve1 / 1576863
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen3 / 5395255
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204685_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.05
Adipocyte7.75
AdrenalCortex12.8
Adrenalgland6.5
Amygdala107.2
Appendix8.35
AtrioventricularNode15.55
BDCA4+_DentriticCells7
Bonemarrow8.2
BronchialEpithelialCells6.6
CD105+_Endothelial7.65
CD14+_Monocytes8
CD19+_BCells(neg._sel.)8.15
CD33+_Myeloid8.55
CD34+7.45
CD4+_Tcells7.2
CD56+_NKCells8.6
CD71+_EarlyErythroid7
CD8+_Tcells6.75
CardiacMyocytes9.8
Caudatenucleus161.85
Cerebellum695.2
CerebellumPeduncles223.25
CiliaryGanglion22.3
CingulateCortex598.15
Colorectaladenocarcinoma6.7
DorsalRootGanglion17.6
FetalThyroid7.35
Fetalbrain141.3
Fetalliver15.25
Fetallung6.55
GlobusPallidus187.15
Heart10
Hypothalamus89.5
Kidney6.55
Leukemia_chronicMyelogenousK-5627.45
Leukemia_promyelocytic-HL-607.25
Leukemialymphoblastic(MOLT-4)8
Liver13.05
Lung8.05
Lymphnode7
Lymphoma_burkitts(Daudi)10.45
Lymphoma_burkitts(Raji)10.35
MedullaOblongata201.35
OccipitalLobe206.55
OlfactoryBulb10.7
Ovary9.3
Pancreas6.25
PancreaticIslet8.8
ParietalLobe180.6
Pituitary11.9
Placenta7.6
Pons166.75
PrefrontalCortex608.8
Prostate8.8
Salivarygland42.65
SkeletalMuscle19.7
Skin11.4
SmoothMuscle8.8
Spinalcord30.7
SubthalamicNucleus253.5
SuperiorCervicalGanglion21.7
TemporalLobe155.75
Testis6.55
TestisGermCell8.1
TestisIntersitial7.65
TestisLeydigCell11.85
TestisSeminiferousTubule6.9
Thalamus133.2
Thymus6.2
Thyroid8.65
Tongue7.85
Tonsil7.95
Trachea6.9
TrigeminalGanglion34.6
Uterus6.25
UterusCorpus8.9
WholeBlood8.05
Wholebrain223.05
colon5.95
pineal_day632.52
pineal_night567.32
retina20.225
small_intestine6.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2847_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.46 ± 0.4
Basal Forebrain7.57 ± 0.25
Basal Part of Pons8.51 ± 0.43
Cerebellar Cortex7.92 ± 0.38
Cerebellar Nuclei7.97 ± 0.42
Claustrum8.72 ± 0.33
Epithalamus6.57 ± 0.38
Frontal Lobe7.76 ± 0.57
Globus Pallidus6.55 ± 0.48
Hypothalamus6.78 ± 0.52
Insula7.55 ± 0.48
Limbic Lobe7.86 ± 0.52
Mesencephalon7.64 ± 0.6
Myelencephalon7.81 ± 0.63
Occipital Lobe8.59 ± 0.52
Parietal Lobe8.2 ± 0.48
Pontine Tegmentum7.76 ± 0.53
Striatum8.08 ± 0.48
Subthalamus7.69 ± 0.32
Temporal Lobe7.87 ± 0.5
Thalamus8.08 ± 0.51
White Matter5.34 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Atp2b2CBCerebellum93.1
100
Atp2b2CTXCerebral cortex100
100
Atp2b2HIPHippocampal region100
100
Atp2b2HPFHippocampal formation100
100
Atp2b2HYHypothalamus92.6
100
Atp2b2LSXLateral septal complex100
100
Atp2b2MBMidbrain100
100
Atp2b2MYMedulla100
100
Atp2b2OLFOlfactory bulb100
100
Atp2b2PPons97.9
100
Atp2b2PALPallidum100
100
Atp2b2RHPRetrohippocampal region100
100
Atp2b2sAMYStriatum-like amygdalar nuclei100
100
Atp2b2STRStriatum100
100
Atp2b2STRdStriatum dorsal region100
100
Atp2b2STRvStriatum ventral region100
100
Atp2b2THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00021308 18 483 500 HLDACETMGNATAICSDK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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