Annotation Detail for NTHL1
Basic Information Top
| Gene Symbol: | NTHL1 ( NTH1,OCTS3 ) |
|---|---|
| Gene Full Name: | nth endonuclease III-like 1 (E. coli) |
| Band: | 16p13.3 |
| Quick Links | Entrez ID:4913; OMIM: 602656; Uniprot ID:NTHL1_HUMAN; ENSEMBL ID: ENSG00000065057; HGNC ID: 8028 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.66196
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 5 / 62319 | 80 |  |
| fetus | 6 / 564012 | 10 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 34 / 1939121 | 17 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 14 / 114246 | 122 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 6 / 119369 | 50 | |
| germ cell tumor | 10 / 263845 | 37 | |
| glioma | 4 / 106883 | 37 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 15 / 103127 | 145 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 54 / 3360307 | 16 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 12 / 125680 | 95 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 7 / 46356 | 151 | |
| skin tumor | 9 / 124949 | 72 | |
| soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 0 / 29757 | 0 | |
| blood | 4 / 123478 | 32 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 24 / 1100989 | 21 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 13 / 211054 | 61 | |
| heart | 0 / 89626 | 0 | |
| intestine | 19 / 234472 | 81 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 0 / 24145 | 0 | |
| liver | 5 / 207743 | 24 | |
| lung | 16 / 336974 | 47 | |
| lymph | 2 / 44270 | 45 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 4 / 153271 | 26 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 6 / 280825 | 21 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 9 / 210574 | 42 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 9 / 96619 | 93 | |
| testis | 3 / 330442 | 9 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 209731_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 43.2 | |
| Adipocyte | 7.9 | |
| AdrenalCortex | 8.3 | |
| Adrenalgland | 6.7 | |
| Amygdala | 8.35 | |
| Appendix | 8 | |
| AtrioventricularNode | 6.1 | |
| BDCA4+_DentriticCells | 14.4 | |
| Bonemarrow | 6.45 | |
| BronchialEpithelialCells | 7.9 | |
| CD105+_Endothelial | 8.2 | |
| CD14+_Monocytes | 8.35 | |
| CD19+_BCells(neg._sel.) | 20.55 | |
| CD33+_Myeloid | 10.4 | |
| CD34+ | 38.4 | |
| CD4+_Tcells | 9.7 | |
| CD56+_NKCells | 13.3 | |
| CD71+_EarlyErythroid | 7.55 | |
| CD8+_Tcells | 7.8 | |
| CardiacMyocytes | 10.3 | |
| Caudatenucleus | 7.15 | |
| Cerebellum | 6.45 | |
| CerebellumPeduncles | 9.15 | |
| CiliaryGanglion | 5.7 | |
| CingulateCortex | 8.25 | |
| Colorectaladenocarcinoma | 8.05 | |
| DorsalRootGanglion | 6.2 | |
| FetalThyroid | 6.05 | |
| Fetalbrain | 7.95 | |
| Fetalliver | 6.9 | |
| Fetallung | 6.55 | |
| GlobusPallidus | 5.9 | |
| Heart | 62.85 | |
| Hypothalamus | 9 | |
| Kidney | 7.25 | |
| Leukemia_chronicMyelogenousK-562 | 7.25 | |
| Leukemia_promyelocytic-HL-60 | 28.05 | |
| Leukemialymphoblastic(MOLT-4) | 8.95 | |
| Liver | 124.05 | |
| Lung | 35.15 | |
| Lymphnode | 6.55 | |
| Lymphoma_burkitts(Daudi) | 10.35 | |
| Lymphoma_burkitts(Raji) | 61.05 | |
| MedullaOblongata | 6.6 | |
| OccipitalLobe | 7.15 | |
| OlfactoryBulb | 6.35 | |
| Ovary | 5.05 | |
| Pancreas | 6.35 | |
| PancreaticIslet | 8.5 | |
| ParietalLobe | 11.85 | |
| Pituitary | 9.35 | |
| Placenta | 7.1 | |
| Pons | 7.6 | |
| PrefrontalCortex | 13.5 | |
| Prostate | 13.65 | |
| Salivarygland | 6.35 | |
| SkeletalMuscle | 9.2 | |
| Skin | 6.25 | |
| SmoothMuscle | 8.05 | |
| Spinalcord | 8.5 | |
| SubthalamicNucleus | 7.25 | |
| SuperiorCervicalGanglion | 9.05 | |
| TemporalLobe | 7.3 | |
| Testis | 6.75 | |
| TestisGermCell | 6.75 | |
| TestisIntersitial | 6.65 | |
| TestisLeydigCell | 7.85 | |
| TestisSeminiferousTubule | 6.85 | |
| Thalamus | 10 | |
| Thymus | 11.9 | |
| Thyroid | 10.95 | |
| Tongue | 7.25 | |
| Tonsil | 6.85 | |
| Trachea | 6.35 | |
| TrigeminalGanglion | 7.9 | |
| Uterus | 6.35 | |
| UterusCorpus | 7.15 | |
| WholeBlood | 8.4 | |
| Wholebrain | 21.5 | |
| colon | 8.55 | |
| pineal_day | 10.06 | |
| pineal_night | 9.82 | |
| retina | 13.5 | |
| small_intestine | 7.65 | |
- Probe name: CUST_7865_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.5 ± 0.42 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.66 ± 0.26 | |
| Basal Part of Pons | 6.37 ± 0.4 | |
| Cerebellar Cortex | 6.09 ± 0.51 | |
| Cerebellar Nuclei | 5.86 ± 0.48 | |
| Claustrum | 5.08 ± 0.8 | |
| Epithalamus | 5.71 ± 0.58 | |
| Frontal Lobe | 6.01 ± 0.52 | |
| Globus Pallidus | 5.37 ± 0.27 | |
| Hypothalamus | 5.9 ± 0.49 | |
| Insula | 5.92 ± 0.4 | |
| Limbic Lobe | 5.48 ± 0.55 | |
| Mesencephalon | 5.7 ± 0.5 | |
| Myelencephalon | 5.72 ± 0.62 | |
| Occipital Lobe | 5.19 ± 0.54 | |
| Parietal Lobe | 5.74 ± 0.5 | |
| Pontine Tegmentum | 5.72 ± 0.49 | |
| Striatum | 5.52 ± 0.47 | |
| Subthalamus | 5.88 ± 0.28 | |
| Temporal Lobe | 5.82 ± 0.51 | |
| Thalamus | 5.87 ± 0.38 | |
| White Matter | 5.6 ± 0.43 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Nthl1 | CB | Cerebellum | 0.13 | |
| 0.28 | | |||
| Nthl1 | CTX | Cerebral cortex | 0.3 | |
| 0.63 | | |||
| Nthl1 | HIP | Hippocampal region | 0.04 | |
| 0.05 | | |||
| Nthl1 | HPF | Hippocampal formation | 0.05 | |
| 0.07 | | |||
| Nthl1 | HY | Hypothalamus | 0.07 | |
| 0.06 | | |||
| Nthl1 | LSX | Lateral septal complex | 0.05 | |
| 0 | | |||
| Nthl1 | MB | Midbrain | 0.05 | |
| 0.06 | | |||
| Nthl1 | MY | Medulla | 0.08 | |
| 0.16 | | |||
| Nthl1 | OLF | Olfactory bulb | 0.36 | |
| 1.37 | | |||
| Nthl1 | P | Pons | 0.05 | |
| 0.09 | | |||
| Nthl1 | PAL | Pallidum | 0.06 | |
| 0.03 | | |||
| Nthl1 | RHP | Retrohippocampal region | 0.06 | |
| 0.09 | | |||
| Nthl1 | sAMY | Striatum-like amygdalar nuclei | 0.13 | |
| 0.23 | | |||
| Nthl1 | STR | Striatum | 0.11 | |
| 0.13 | | |||
| Nthl1 | STRd | Striatum dorsal region | 0.1 | |
| 0.13 | | |||
| Nthl1 | STRv | Striatum ventral region | 0.12 | |
| 0.12 | | |||
| Nthl1 | TH | Thalamus | 0.19 | |
| 0.34 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00029398 | 20 | 107 | 126 | DAPVDHLGTEHCYDSSAPPK | Peptide Atlas |