AutismKB 2.0

Annotation Detail for NTN3


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Basic Information Top
Gene Symbol:NTN3 ( NTN2L )
Gene Full Name: netrin 3
Band: 16p13.3
Quick LinksEntrez ID:4917; OMIM: 602349; Uniprot ID:NET3_HUMAN; ENSEMBL ID: ENSG00000162068; HGNC ID: 8030
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult0 / 19391210 
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult3 / 19391211
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult78 / 193912140
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal0 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal8 / 33603072
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor2 / 17290115
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor16 / 96359166
lung tumor7 / 10312767
lymphoma3 / 7175541
non-neoplasia9 / 9725092
normal294 / 336030787
ovarian tumor3 / 7668239
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor9 / 9025799
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor9 / 9417895
cervical tumor12 / 34366349
chondrosarcoma0 / 828230 
colorectal tumor14 / 114246122
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor11 / 13630280
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor5 / 9635951
lung tumor38 / 103127368
lymphoma0 / 717550 
non-neoplasia244 / 972502508
normal577 / 3360307171
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor13 / 90257144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow8 / 48801163
brain1 / 11009890 
cervix0 / 481710 
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus2 / 2020998
eye1 / 2110544
heart0 / 896260 
intestine17 / 23447272
kidney5 / 21177723
larynx3 / 24145124
liver16 / 20774377
lung23 / 33697468
lymph0 / 442700 
lymph node29 / 91610316
mammary gland7 / 15327145
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary4 / 10205139
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx85 / 413282056
pituitary gland0 / 165850 
placenta3 / 28082510
prostate5 / 18934526
salivary gland0 / 201550 
skin0 / 2105740 
spleen10 / 53952185
stomach12 / 96619124
testis8 / 33044224
thymus1 / 8113112
thyroid1 / 4747321
tonsil4 / 16999235
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular2 / 5178038
adipose tissue7 / 13106534
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain15 / 110098913
cervix16 / 48171332
connective tissue244 / 1492551634
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus2 / 2020998
eye2 / 2110549
heart0 / 896260 
intestine201 / 234472857
kidney1 / 2117774
larynx3 / 24145124
liver5 / 20774324
lung52 / 336974154
lymph0 / 442700 
lymph node21 / 91610229
mammary gland12 / 15327178
mouth7 / 67052104
muscle0 / 1077150 
nerve0 / 157680 
ovary4 / 10205139
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx15 / 41328362
pituitary gland0 / 165850 
placenta12 / 28082542
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen57 / 539521056
stomach214 / 966192214
testis2 / 3304426
thymus41 / 81131505
thyroid2 / 4747342
tonsil15 / 16999882
trachea5 / 5241395
umbilical cord0 / 136800 
uterus15 / 23287864
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207640_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.55
Adipocyte3.6
AdrenalCortex5.15
Adrenalgland3.05
Amygdala3.85
Appendix3.65
AtrioventricularNode4.85
BDCA4+_DentriticCells4.05
Bonemarrow3.6
BronchialEpithelialCells3.55
CD105+_Endothelial3.7
CD14+_Monocytes4.3
CD19+_BCells(neg._sel.)3.95
CD33+_Myeloid4.7
CD34+4.65
CD4+_Tcells4.05
CD56+_NKCells4.4
CD71+_EarlyErythroid3.6
CD8+_Tcells3.6
CardiacMyocytes5.35
Caudatenucleus3.25
Cerebellum2.9
CerebellumPeduncles4.1
CiliaryGanglion2.65
CingulateCortex3.8
Colorectaladenocarcinoma3.65
DorsalRootGanglion3
FetalThyroid3.55
Fetalbrain3.65
Fetalliver3.15
Fetallung3
GlobusPallidus2.65
Heart8.2
Hypothalamus3.95
Kidney3
Leukemia_chronicMyelogenousK-5623.35
Leukemia_promyelocytic-HL-603.2
Leukemialymphoblastic(MOLT-4)2.9
Liver5.25
Lung4.05
Lymphnode3.15
Lymphoma_burkitts(Daudi)4.7
Lymphoma_burkitts(Raji)5.45
MedullaOblongata3.35
OccipitalLobe3.25
OlfactoryBulb2.85
Ovary2.4
Pancreas2.95
PancreaticIslet3.9
ParietalLobe3.85
Pituitary4.25
Placenta3.8
Pons3.5
PrefrontalCortex4.6
Prostate4.3
Salivarygland2.9
SkeletalMuscle4.15
Skin3.95
SmoothMuscle4.15
Spinalcord3.9
SubthalamicNucleus3.4
SuperiorCervicalGanglion4.3
TemporalLobe3.3
Testis3.1
TestisGermCell3.05
TestisIntersitial3.1
TestisLeydigCell3.6
TestisSeminiferousTubule3.1
Thalamus3.8
Thymus2.9
Thyroid4.55
Tongue3.65
Tonsil3.55
Trachea3.05
TrigeminalGanglion3.7
Uterus3
UterusCorpus3.3
WholeBlood3.95
Wholebrain3.1
colon3.65
pineal_day4.6
pineal_night4.46
retina4.45
small_intestine3.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8604_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.6 ± 0.71
Basal Forebrain3.75 ± 0.51
Basal Part of Pons3.57 ± 0.76
Cerebellar Cortex3.24 ± 0.67
Cerebellar Nuclei3.66 ± 0.65
Claustrum3.98 ± 0.69
Epithalamus3.31 ± 0.41
Frontal Lobe3.45 ± 0.71
Globus Pallidus3.95 ± 0.68
Hypothalamus3.63 ± 0.58
Insula3.17 ± 0.77
Limbic Lobe3.62 ± 0.75
Mesencephalon3.63 ± 0.68
Myelencephalon3.57 ± 0.72
Occipital Lobe3.65 ± 0.62
Parietal Lobe3.43 ± 0.73
Pontine Tegmentum3.37 ± 0.54
Striatum3.71 ± 0.57
Subthalamus2.65 ± 0.63
Temporal Lobe3.46 ± 0.65
Thalamus3.52 ± 0.68
White Matter3.54 ± 0.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ntn2lCBCerebellum8.5
9.88
Ntn2lCTXCerebral cortex4.98
3.38
Ntn2lHIPHippocampal region7.09
6.5
Ntn2lHPFHippocampal formation5.73
4.82
Ntn2lHYHypothalamus0.68
0.59
Ntn2lLSXLateral septal complex0.95
0.74
Ntn2lMBMidbrain1.85
2.21
Ntn2lMYMedulla3.86
3.96
Ntn2lOLFOlfactory bulb11.88
9.89
Ntn2lPPons2.44
2.66
Ntn2lPALPallidum1.34
1.3
Ntn2lRHPRetrohippocampal region3.47
2.51
Ntn2lsAMYStriatum-like amygdalar nuclei0.88
0.6
Ntn2lSTRStriatum1.78
1.38
Ntn2lSTRdStriatum dorsal region1.37
1.23
Ntn2lSTRvStriatum ventral region3.47
2.2
Ntn2lTHThalamus1.64
1.86
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018