AutismKB 2.0

Annotation Detail for ROR1


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Basic Information Top
Gene Symbol:ROR1 ( MGC99659,NTRKR1,dJ537F10.1 )
Gene Full Name: receptor tyrosine kinase-like orphan receptor 1
Band: 1p31.3
Quick LinksEntrez ID:4919; OMIM: 602336; Uniprot ID:ROR1_HUMAN; ENSEMBL ID: ENSG00000185483; HGNC ID: 10256
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst4 / 6231964
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult17 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor6 / 6895987
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal39 / 336030711
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye3 / 21105414
heart3 / 8962633
intestine4 / 23447217
kidney8 / 21177737
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate3 / 18934515
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211057_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.5
Adipocyte4.7
AdrenalCortex5.15
Adrenalgland4.05
Amygdala5.05
Appendix5.2
AtrioventricularNode3.95
BDCA4+_DentriticCells4.85
Bonemarrow4.8
BronchialEpithelialCells4.6
CD105+_Endothelial4.8
CD14+_Monocytes5.1
CD19+_BCells(neg._sel.)5.05
CD33+_Myeloid5.85
CD34+5.85
CD4+_Tcells5.05
CD56+_NKCells5.55
CD71+_EarlyErythroid4.5
CD8+_Tcells4.6
CardiacMyocytes6.2
Caudatenucleus4.25
Cerebellum3.85
CerebellumPeduncles5.4
CiliaryGanglion3.45
CingulateCortex4.95
Colorectaladenocarcinoma4.8
DorsalRootGanglion3.7
FetalThyroid4.6
Fetalbrain4.8
Fetalliver4.1
Fetallung3.95
GlobusPallidus3.55
Heart6.25
Hypothalamus5.15
Kidney3.9
Leukemia_chronicMyelogenousK-5624.3
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.7
Liver6.6
Lung5.3
Lymphnode4.1
Lymphoma_burkitts(Daudi)6.4
Lymphoma_burkitts(Raji)6.8
MedullaOblongata4.2
OccipitalLobe4.25
OlfactoryBulb3.75
Ovary3.15
Pancreas3.85
PancreaticIslet5.15
ParietalLobe5.15
Pituitary5.55
Placenta4.55
Pons4.65
PrefrontalCortex5.7
Prostate10.7
Salivarygland3.95
SkeletalMuscle5.95
Skin3.8
SmoothMuscle5.4
Spinalcord5.05
SubthalamicNucleus4.3
SuperiorCervicalGanglion5.75
TemporalLobe4.35
Testis4.1
TestisGermCell3.85
TestisIntersitial3.95
TestisLeydigCell4.7
TestisSeminiferousTubule4.1
Thalamus4.8
Thymus3.8
Thyroid5.95
Tongue4.9
Tonsil4.65
Trachea3.95
TrigeminalGanglion7.15
Uterus4.3
UterusCorpus4.25
WholeBlood5
Wholebrain3.9
colon4.8
pineal_day5.82
pineal_night5.7
retina5.65
small_intestine4.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8881_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.92 ± 1.07
Basal Forebrain2.79 ± 0.61
Basal Part of Pons2.12 ± 0.38
Cerebellar Cortex3.22 ± 0.52
Cerebellar Nuclei2.85 ± 0.66
Claustrum3.48 ± 1.03
Epithalamus2.43 ± 0.69
Frontal Lobe2.39 ± 0.8
Globus Pallidus2.83 ± 0.73
Hypothalamus2.53 ± 0.73
Insula2.33 ± 0.52
Limbic Lobe2.54 ± 0.67
Mesencephalon2.8 ± 0.76
Myelencephalon2.62 ± 0.75
Occipital Lobe2.72 ± 0.64
Parietal Lobe2.63 ± 1
Pontine Tegmentum2.64 ± 0.75
Striatum2.38 ± 0.79
Subthalamus2.72 ± 0.85
Temporal Lobe2.4 ± 0.67
Thalamus2.54 ± 0.66
White Matter3.03 ± 0.57
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ror1CBCerebellum5.33
4.77
Ror1CTXCerebral cortex5.55
3.79
Ror1HIPHippocampal region6.36
6.19
Ror1HPFHippocampal formation6.2
5.38
Ror1HYHypothalamus0.78
0.57
Ror1LSXLateral septal complex0.24
0.15
Ror1MBMidbrain0.37
0.36
Ror1MYMedulla1.26
1.18
Ror1OLFOlfactory bulb5.7
3.89
Ror1PPons0.52
0.55
Ror1PALPallidum1.3
1.08
Ror1RHPRetrohippocampal region6.09
4.45
Ror1sAMYStriatum-like amygdalar nuclei0.47
0.43
Ror1STRStriatum2.57
1.81
Ror1STRdStriatum dorsal region2.35
1.63
Ror1STRvStriatum ventral region5.21
3.48
Ror1THThalamus1.38
1.06
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00095515 19 250 268 DECEILENVLCQTEYIFAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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