AutismKB 2.0

Annotation Detail for ROR2


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Basic Information Top
Gene Symbol:ROR2 ( BDB,BDB1,MGC163394,NTRKR2 )
Gene Full Name: receptor tyrosine kinase-like orphan receptor 2
Band: 9q22.31
Quick LinksEntrez ID:4920; OMIM: 602337; Uniprot ID:ROR2_HUMAN; ENSEMBL ID: ENSG00000169071; HGNC ID: 10257
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal58 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye0 / 2110540 
heart2 / 8962622
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid6 / 20539292
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate8 / 18934542
salivary gland1 / 2015549
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis8 / 33044224
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205578_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.15
Adipocyte10.85
AdrenalCortex14.9
Adrenalgland12.75
Amygdala10.9
Appendix16.4
AtrioventricularNode13.2
BDCA4+_DentriticCells8.95
Bonemarrow16.75
BronchialEpithelialCells10.25
CD105+_Endothelial11.15
CD14+_Monocytes11.85
CD19+_BCells(neg._sel.)12.35
CD33+_Myeloid12.95
CD34+12.7
CD4+_Tcells10.6
CD56+_NKCells11.6
CD71+_EarlyErythroid11.15
CD8+_Tcells9.2
CardiacMyocytes19.25
Caudatenucleus10.4
Cerebellum9.35
CerebellumPeduncles15
CiliaryGanglion9.45
CingulateCortex12.8
Colorectaladenocarcinoma10.8
DorsalRootGanglion10.5
FetalThyroid14.45
Fetalbrain10.55
Fetalliver9.75
Fetallung9.15
GlobusPallidus10.1
Heart17.15
Hypothalamus12.2
Kidney12
Leukemia_chronicMyelogenousK-56210.5
Leukemia_promyelocytic-HL-609.9
Leukemialymphoblastic(MOLT-4)8.8
Liver16.1
Lung11.75
Lymphnode9.05
Lymphoma_burkitts(Daudi)15.75
Lymphoma_burkitts(Raji)16.45
MedullaOblongata12.3
OccipitalLobe9.9
OlfactoryBulb8.45
Ovary8.8
Pancreas9.3
PancreaticIslet13
ParietalLobe12.7
Pituitary13.95
Placenta10.95
Pons15.6
PrefrontalCortex11.5
Prostate12.5
Salivarygland9.4
SkeletalMuscle15.85
Skin12.05
SmoothMuscle12.25
Spinalcord11.85
SubthalamicNucleus10.55
SuperiorCervicalGanglion21.9
TemporalLobe11.25
Testis9.85
TestisGermCell9.3
TestisIntersitial9.4
TestisLeydigCell13.2
TestisSeminiferousTubule10
Thalamus11.85
Thymus8.3
Thyroid13.85
Tongue12.3
Tonsil11.45
Trachea10.45
TrigeminalGanglion18.9
Uterus9.55
UterusCorpus11.6
WholeBlood10.55
Wholebrain8.4
colon11.1
pineal_day12.38
pineal_night12.7
retina14.9
small_intestine10.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P101704
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.19 ± 1.06
Basal Forebrain1.69 ± 0.25
Basal Part of Pons1.33 ± 0.42
Cerebellar Cortex1.46 ± 0.64
Cerebellar Nuclei1.99 ± 0.78
Claustrum2.53 ± 0.84
Epithalamus1.36 ± 0.73
Frontal Lobe1.55 ± 0.7
Globus Pallidus2.22 ± 0.37
Hypothalamus1.77 ± 0.67
Insula1.5 ± 0.5
Limbic Lobe1.68 ± 0.7
Mesencephalon1.84 ± 0.69
Myelencephalon1.75 ± 0.67
Occipital Lobe1.69 ± 0.59
Parietal Lobe1.65 ± 0.7
Pontine Tegmentum1.68 ± 0.7
Striatum1.86 ± 0.56
Subthalamus1.81 ± 0.6
Temporal Lobe1.59 ± 0.63
Thalamus1.63 ± 0.57
White Matter2.12 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ror2CBCerebellum100
100
Ror2CTXCerebral cortex100
100
Ror2HIPHippocampal region86.94
100
Ror2HPFHippocampal formation97.33
100
Ror2HYHypothalamus50.44
55.46
Ror2LSXLateral septal complex30.72
23.58
Ror2MBMidbrain43.92
42.85
Ror2MYMedulla58.66
79.32
Ror2OLFOlfactory bulb100
100
Ror2PPons45.44
54.87
Ror2PALPallidum69.31
86.07
Ror2RHPRetrohippocampal region100
100
Ror2sAMYStriatum-like amygdalar nuclei100
100
Ror2STRStriatum100
100
Ror2STRdStriatum dorsal region100
100
Ror2STRvStriatum ventral region100
100
Ror2THThalamus71.47
72.84
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00499409 18 490 507 GHLFGPAPGEQTQAVAIK Peptide Atlas
ROR2_HUMAN_561 8 561 568 LHEFLVMR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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