AutismKB 2.0

Annotation Detail for NUP98


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Basic Information Top
Gene Symbol:NUP98 ( ADIR2,NUP196,NUP96 )
Gene Full Name: nucleoporin 98kDa
Band: 11p15.4
Quick LinksEntrez ID:4928; OMIM: 601021; Uniprot ID:NUP98_HUMAN; ENSEMBL ID: ENSG00000110713; HGNC ID: 8068
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst4 / 6231964
fetus49 / 56401286
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult138 / 193912171
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor4 / 34366116
chondrosarcoma21 / 82823253
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor10 / 26384537
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor8 / 10312777
lymphoma2 / 7175527
non-neoplasia4 / 9725041
normal231 / 336030768
ovarian tumor3 / 7668239
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor14 / 124949112
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites5 / 40015124
bladder0 / 297570 
blood6 / 12347848
bone10 / 71655139
bone marrow0 / 488010 
brain48 / 110098943
cervix5 / 48171103
connective tissue15 / 149255100
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus0 / 202090 
eye16 / 21105475
heart5 / 8962655
intestine18 / 23447276
kidney2 / 2117779
larynx2 / 2414582
liver5 / 20774324
lung29 / 33697486
lymph2 / 4427045
lymph node17 / 91610185
mammary gland8 / 15327152
mouth2 / 6705229
muscle5 / 10771546
nerve0 / 157680 
ovary7 / 10205168
pancreas18 / 21481283
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta11 / 28082539
prostate3 / 18934515
salivary gland0 / 201550 
skin17 / 21057480
spleen3 / 5395255
stomach3 / 9661931
testis72 / 330442217
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus22 / 23287894
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203194_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts29.7
Adipocyte5.45
AdrenalCortex5.8
Adrenalgland4.65
Amygdala5.45
Appendix5.5
AtrioventricularNode4.15
BDCA4+_DentriticCells7.9
Bonemarrow5.55
BronchialEpithelialCells5.45
CD105+_Endothelial11.55
CD14+_Monocytes6
CD19+_BCells(neg._sel.)6
CD33+_Myeloid8.35
CD34+31
CD4+_Tcells6.8
CD56+_NKCells7.2
CD71+_EarlyErythroid12.55
CD8+_Tcells14.1
CardiacMyocytes8.75
Caudatenucleus4.75
Cerebellum4.4
CerebellumPeduncles6.05
CiliaryGanglion3.8
CingulateCortex5.55
Colorectaladenocarcinoma17.55
DorsalRootGanglion4.65
FetalThyroid5.4
Fetalbrain5.3
Fetalliver4.75
Fetallung4.7
GlobusPallidus4
Heart6.95
Hypothalamus5.55
Kidney4.4
Leukemia_chronicMyelogenousK-5625
Leukemia_promyelocytic-HL-604.9
Leukemialymphoblastic(MOLT-4)10.5
Liver7.25
Lung6
Lymphnode4.5
Lymphoma_burkitts(Daudi)7.05
Lymphoma_burkitts(Raji)7.75
MedullaOblongata5
OccipitalLobe4.8
OlfactoryBulb4.35
Ovary3.65
Pancreas4.45
PancreaticIslet5.9
ParietalLobe5.8
Pituitary6.3
Placenta10.05
Pons5.25
PrefrontalCortex6.35
Prostate6.4
Salivarygland4.35
SkeletalMuscle6.25
Skin4.2
SmoothMuscle6.35
Spinalcord5.8
SubthalamicNucleus4.95
SuperiorCervicalGanglion6.3
TemporalLobe5.05
Testis129.05
TestisGermCell265.25
TestisIntersitial188.6
TestisLeydigCell123.7
TestisSeminiferousTubule59.5
Thalamus5.4
Thymus5.6
Thyroid6.7
Tongue5.3
Tonsil5.45
Trachea4.6
TrigeminalGanglion5.6
Uterus4.5
UterusCorpus4.9
WholeBlood8.5
Wholebrain4.65
colon5.65
pineal_day6.94
pineal_night6.76
retina6.75
small_intestine5.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P308032
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.03 ± 0.36
Basal Forebrain6.32 ± 0.23
Basal Part of Pons6.16 ± 0.28
Cerebellar Cortex6.4 ± 0.22
Cerebellar Nuclei6.32 ± 0.32
Claustrum6.4 ± 0.49
Epithalamus6.27 ± 0.34
Frontal Lobe6.23 ± 0.28
Globus Pallidus6.21 ± 0.27
Hypothalamus6.52 ± 0.34
Insula6.22 ± 0.31
Limbic Lobe6.01 ± 0.29
Mesencephalon6.27 ± 0.38
Myelencephalon6.2 ± 0.36
Occipital Lobe6.37 ± 0.29
Parietal Lobe6.18 ± 0.37
Pontine Tegmentum6.25 ± 0.33
Striatum6.11 ± 0.36
Subthalamus6.37 ± 0.13
Temporal Lobe6.13 ± 0.34
Thalamus6.28 ± 0.3
White Matter7.27 ± 0.22
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NUP98_HUMAN_1201 6 1201 1206 LSLRQR PRIDE
NUP98_HUMAN_1207 7 1207 1213 KPDEDMK PRIDE
NUP98_HUMAN_1343 15 1343 1357 ISEACSLAQQSGDHR PRIDE
NUP98_HUMAN_1414 12 1414 1425 KQINVCSQLDWK PRIDE
NUP98_HUMAN_1503 11 1503 1513 HYDLNQLLEPR PRIDE
NUP98_HUMAN_1631 9 1631 1639 HLEALCLFK PRIDE
NUP98_HUMAN_1653 16 1653 1668 HLASDAIINENYDYLK PRIDE
NUP98_HUMAN_1669 11 1669 1679 GFLEDLAPPER PRIDE
NUP98_HUMAN_176 10 176 185 AGVSTNISTK PRIDE
NUP98_HUMAN_533 10 533 542 LKPTNPAAQK PRIDE
NUP98_HUMAN_543 9 543 551 ALTTPTHYK PRIDE
NUP98_HUMAN_720 19 720 738 EEIENNSYHMHPAGIILTK PRIDE
NUP98_HUMAN_739 14 739 752 VGYYTIPSMDDLAK PRIDE
NUP98_HUMAN_819 13 819 831 AEVTLDGVWPTDK PRIDE
NUP98_HUMAN_819 16 819 834 AEVTLDGVWPTDKTSR PRIDE
NUP98_HUMAN_843 9 843 851 LADINYEGR PRIDE
NUP98_HUMAN_883 16 883 898 YGLQDSDEEEEEHPSK PRIDE
PAp00003251 13 1572 1584 HCQLLETPESWAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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