AutismKB 2.0

Annotation Detail for GPX8


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Basic Information Top
Gene Symbol:GPX8 ( UNQ847 )
Gene Full Name: glutathione peroxidase 8 (putative)
Band: 5q11.2
Quick LinksEntrez ID:493869; OMIM: NA; Uniprot ID:GPX8_HUMAN; ENSEMBL ID: ENSG00000164294; HGNC ID: 33100
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body17 / 70761240
blastocyst1 / 6231916
fetus21 / 56401237
neonate3 / 3109796
infant0 / 236200 
juvenile1 / 5555617
adult81 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma13 / 82823156
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor19 / 26384572
glioma5 / 10688346
head and neck tumor6 / 13630244
kidney tumor5 / 6895972
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia12 / 97250123
normal134 / 336030739
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood0 / 1234780 
bone11 / 71655153
bone marrow1 / 4880120
brain17 / 110098915
cervix1 / 4817120
connective tissue20 / 149255133
ear3 / 16212185
embryonic tissue29 / 215722134
esophagus0 / 202090 
eye5 / 21105423
heart6 / 8962666
intestine4 / 23447217
kidney15 / 21177770
larynx1 / 2414541
liver4 / 20774319
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth4 / 6705259
muscle1 / 1077159
nerve1 / 1576863
ovary3 / 10205129
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta23 / 28082581
prostate1 / 1893455
salivary gland0 / 201550 
skin18 / 21057485
spleen0 / 539520 
stomach7 / 9661972
testis25 / 33044275
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea15 / 52413286
umbilical cord0 / 136800 
uterus9 / 23287838
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P876522
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.44 ± 1.03
Basal Forebrain2.26 ± 0.63
Basal Part of Pons1.52 ± 0.44
Cerebellar Cortex1.7 ± 0.48
Cerebellar Nuclei2.48 ± 0.67
Claustrum2.74 ± 0.78
Epithalamus4.13 ± 0.68
Frontal Lobe2.05 ± 0.85
Globus Pallidus3.75 ± 0.54
Hypothalamus2.41 ± 0.8
Insula2.06 ± 0.8
Limbic Lobe2.07 ± 0.78
Mesencephalon2.29 ± 0.81
Myelencephalon2.2 ± 0.81
Occipital Lobe2.17 ± 0.86
Parietal Lobe2.12 ± 0.79
Pontine Tegmentum2.33 ± 0.84
Striatum3.03 ± 0.79
Subthalamus2.15 ± 0.57
Temporal Lobe1.94 ± 0.75
Thalamus2.02 ± 0.67
White Matter2.61 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2310016C16RikCBCerebellum0.16
0.37
2310016C16RikCTXCerebral cortex4.22
3.6
2310016C16RikHIPHippocampal region4.73
6.2
2310016C16RikHPFHippocampal formation3.88
5.44
2310016C16RikHYHypothalamus5.82
5.36
2310016C16RikLSXLateral septal complex6.98
9.94
2310016C16RikMBMidbrain0.78
1.7
2310016C16RikMYMedulla1.48
2.6
2310016C16RikOLFOlfactory bulb9.23
7.47
2310016C16RikPPons2.36
4.74
2310016C16RikPALPallidum4.07
3.32
2310016C16RikRHPRetrohippocampal region2.18
4.25
2310016C16RiksAMYStriatum-like amygdalar nuclei1.51
1.45
2310016C16RikSTRStriatum3.34
3.18
2310016C16RikSTRdStriatum dorsal region3.19
2.55
2310016C16RikSTRvStriatum ventral region3.08
3.15
2310016C16RikTHThalamus3.7
3.98
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00500957 11 129 139 NYGVTFPIFHK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018