AutismKB 2.0

Annotation Detail for PHOSPHO2


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Basic Information Top
Gene Symbol:PHOSPHO2 ( MGC111048,MGC22679 )
Gene Full Name: phosphatase, orphan 2
Band: 2q31.1
Quick LinksEntrez ID:493911; OMIM: NA; Uniprot ID:PHOP2_HUMAN; ENSEMBL ID: ENSG00000144362; HGNC ID: 28316
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus14 / 56401224
neonate0 / 310970 
infant3 / 23620127
juvenile1 / 5555617
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal63 / 336030718
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma6 / 46356129
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder3 / 29757100
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain23 / 110098920
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye8 / 21105437
heart3 / 8962633
intestine3 / 23447212
kidney5 / 21177723
larynx0 / 241450 
liver8 / 20774338
lung6 / 33697417
lymph1 / 4427022
lymph node0 / 916100 
mammary gland6 / 15327139
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach6 / 9661962
testis9 / 33044227
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8113_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.34 ± 0.4
Basal Forebrain6.41 ± 0.16
Basal Part of Pons5.98 ± 0.22
Cerebellar Cortex6.73 ± 0.22
Cerebellar Nuclei5.96 ± 0.21
Claustrum5.84 ± 0.62
Epithalamus6.96 ± 0.32
Frontal Lobe6.21 ± 0.36
Globus Pallidus6.3 ± 0.41
Hypothalamus6.68 ± 0.35
Insula6.33 ± 0.21
Limbic Lobe6.34 ± 0.36
Mesencephalon6.43 ± 0.34
Myelencephalon6.28 ± 0.43
Occipital Lobe6.61 ± 0.45
Parietal Lobe6.24 ± 0.38
Pontine Tegmentum6.3 ± 0.45
Striatum6.36 ± 0.46
Subthalamus5.75 ± 0.8
Temporal Lobe6.25 ± 0.33
Thalamus6.16 ± 0.28
White Matter6.71 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Phospho2CBCerebellum0
0
Phospho2CTXCerebral cortex0
0
Phospho2HIPHippocampal region0
0
Phospho2HPFHippocampal formation0
0
Phospho2HYHypothalamus0
0
Phospho2LSXLateral septal complex0
0
Phospho2MBMidbrain0
0
Phospho2MYMedulla0
0
Phospho2OLFOlfactory bulb0
0
Phospho2PPons0
0
Phospho2PALPallidum0
0
Phospho2RHPRetrohippocampal region0
0
Phospho2sAMYStriatum-like amygdalar nuclei0
0
Phospho2STRStriatum0
0
Phospho2STRdStriatum dorsal region0
0
Phospho2STRvStriatum ventral region0
0
Phospho2THThalamus0
0
Peptide Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018