AutismKB 2.0

Annotation Detail for TBC1D25


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Basic Information Top
Gene Symbol:TBC1D25 ( MG81,MGC126866,MGC126868,MGC149731,MGC149732,OATL1 )
Gene Full Name: TBC1 domain family, member 25
Band: Xp11.23
Quick LinksEntrez ID:4943; OMIM: 311240; Uniprot ID:TBC25_HUMAN; ENSEMBL ID: ENSG00000068354; HGNC ID: 8092
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult78 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor11 / 26384541
glioma5 / 10688346
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor5 / 9635951
lung tumor4 / 10312738
lymphoma5 / 7175569
non-neoplasia1 / 9725010
normal130 / 336030738
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone5 / 7165569
bone marrow0 / 488010 
brain47 / 110098942
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye10 / 21105447
heart5 / 8962655
intestine4 / 23447217
kidney6 / 21177728
larynx1 / 2414541
liver6 / 20774328
lung19 / 33697456
lymph4 / 4427090
lymph node2 / 9161021
mammary gland1 / 1532716
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary4 / 10205139
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta44 / 280825156
prostate4 / 18934521
salivary gland4 / 20155198
skin8 / 21057437
spleen0 / 539520 
stomach1 / 9661910
testis11 / 33044233
thymus1 / 8113112
thyroid0 / 474730 
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P159688
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.61 ± 0.53
Basal Forebrain4.13 ± 0.39
Basal Part of Pons4.55 ± 0.57
Cerebellar Cortex4.75 ± 0.28
Cerebellar Nuclei4.31 ± 0.54
Claustrum4.43 ± 0.57
Epithalamus3.81 ± 0.51
Frontal Lobe4.52 ± 0.48
Globus Pallidus3.43 ± 0.54
Hypothalamus4.01 ± 0.64
Insula4.85 ± 0.47
Limbic Lobe4.6 ± 0.44
Mesencephalon4.39 ± 0.7
Myelencephalon4.35 ± 0.52
Occipital Lobe4.32 ± 0.58
Parietal Lobe4.41 ± 0.46
Pontine Tegmentum4.41 ± 0.54
Striatum4 ± 0.54
Subthalamus4.21 ± 0.18
Temporal Lobe4.49 ± 0.48
Thalamus4.22 ± 0.56
White Matter3.02 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Oatl1CBCerebellum0.45
0.83
Oatl1CTXCerebral cortex0.16
0.2
Oatl1HIPHippocampal region0.09
0.15
Oatl1HPFHippocampal formation0.09
0.13
Oatl1HYHypothalamus0.02
0.04
Oatl1LSXLateral septal complex0
0
Oatl1MBMidbrain0.18
0.4
Oatl1MYMedulla0.13
0.1
Oatl1OLFOlfactory bulb0.18
0.19
Oatl1PPons0.11
0.11
Oatl1PALPallidum0.04
0.02
Oatl1RHPRetrohippocampal region0.09
0.09
Oatl1sAMYStriatum-like amygdalar nuclei0.08
0.2
Oatl1STRStriatum0.04
0.05
Oatl1STRdStriatum dorsal region0.02
0.04
Oatl1STRvStriatum ventral region0.07
0.03
Oatl1THThalamus0.32
0.58
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018