AutismKB 2.0

Annotation Detail for RNF165


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Basic Information Top
Gene Symbol:RNF165 ( ARKL2 )
Gene Full Name: ring finger protein 165
Band: 18q21.1
Quick LinksEntrez ID:494470; OMIM: NA; Uniprot ID:RN165_HUMAN; ENSEMBL ID: ENSG00000141622; HGNC ID: 31696
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult11 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor9 / 26384534
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal60 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain39 / 110098935
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_702_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.01 ± 0.68
Basal Forebrain4.15 ± 0.47
Basal Part of Pons4.64 ± 0.4
Cerebellar Cortex4.82 ± 0.52
Cerebellar Nuclei4 ± 0.33
Claustrum4.83 ± 0.56
Epithalamus4.37 ± 0.71
Frontal Lobe4.89 ± 0.65
Globus Pallidus2.67 ± 0.53
Hypothalamus4.03 ± 0.55
Insula5.13 ± 0.4
Limbic Lobe5.26 ± 0.54
Mesencephalon4.48 ± 0.83
Myelencephalon4.63 ± 0.61
Occipital Lobe4.3 ± 0.69
Parietal Lobe4.76 ± 0.61
Pontine Tegmentum4.76 ± 0.79
Striatum4.27 ± 0.8
Subthalamus4.35 ± 0.5
Temporal Lobe5.13 ± 0.46
Thalamus4.45 ± 0.67
White Matter2.38 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gm96CBCerebellum70.41
100
Gm96CTXCerebral cortex100
92.51
Gm96HIPHippocampal region72.47
100
Gm96HPFHippocampal formation84.23
100
Gm96HYHypothalamus37.03
28.97
Gm96LSXLateral septal complex74.02
60.24
Gm96MBMidbrain38.1
33.47
Gm96MYMedulla32.98
33.12
Gm96OLFOlfactory bulb100
97.07
Gm96PPons32.06
30.33
Gm96PALPallidum39.68
34.47
Gm96RHPRetrohippocampal region100
95.13
Gm96sAMYStriatum-like amygdalar nuclei67.45
50.79
Gm96STRStriatum74.08
56.72
Gm96STRdStriatum dorsal region74.67
56.97
Gm96STRvStriatum ventral region76.16
56.83
Gm96THThalamus51.54
43.37
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018