AutismKB 2.0

Annotation Detail for OGG1


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Basic Information Top
Gene Symbol:OGG1 ( HMMH,HOGG1,MUTM,OGH1 )
Gene Full Name: 8-oxoguanine DNA glycosylase
Band: 3p25.3
Quick LinksEntrez ID:4968; OMIM: 601982; Uniprot ID:OGG1_HUMAN; ENSEMBL ID: ENSG00000114026; HGNC ID: 8125
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult62 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor4 / 34366116
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor6 / 26384522
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma4 / 7175555
non-neoplasia2 / 9725020
normal112 / 336030733
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood6 / 12347848
bone3 / 7165541
bone marrow1 / 4880120
brain43 / 110098939
cervix8 / 48171166
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine3 / 23447212
kidney15 / 21177770
larynx1 / 2414541
liver2 / 2077439
lung11 / 33697432
lymph2 / 4427045
lymph node7 / 9161076
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta8 / 28082528
prostate13 / 18934568
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach10 / 96619103
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205301_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts17.7
Adipocyte19.6
AdrenalCortex24.65
Adrenalgland16.25
Amygdala12.7
Appendix19.2
AtrioventricularNode30.75
BDCA4+_DentriticCells11.65
Bonemarrow17.95
BronchialEpithelialCells12.85
CD105+_Endothelial14.55
CD14+_Monocytes15.3
CD19+_BCells(neg._sel.)15.3
CD33+_Myeloid16.25
CD34+17.85
CD4+_Tcells14.5
CD56+_NKCells17.25
CD71+_EarlyErythroid14.75
CD8+_Tcells12.9
CardiacMyocytes32.9
Caudatenucleus22.15
Cerebellum12.6
CerebellumPeduncles32.7
CiliaryGanglion16.3
CingulateCortex35.25
Colorectaladenocarcinoma13.65
DorsalRootGanglion18.3
FetalThyroid15.5
Fetalbrain15.95
Fetalliver13.75
Fetallung10.15
GlobusPallidus17.4
Heart36.85
Hypothalamus13.85
Kidney28.05
Leukemia_chronicMyelogenousK-56213.7
Leukemia_promyelocytic-HL-6014.95
Leukemialymphoblastic(MOLT-4)10.6
Liver22.35
Lung18.6
Lymphnode14.05
Lymphoma_burkitts(Daudi)46.55
Lymphoma_burkitts(Raji)34.45
MedullaOblongata14.75
OccipitalLobe13.7
OlfactoryBulb14.6
Ovary14.35
Pancreas13.45
PancreaticIslet14.15
ParietalLobe24.95
Pituitary16.2
Placenta14.3
Pons15.25
PrefrontalCortex14.05
Prostate21
Salivarygland16.45
SkeletalMuscle25.4
Skin25.45
SmoothMuscle14.6
Spinalcord15.9
SubthalamicNucleus44.65
SuperiorCervicalGanglion35.85
TemporalLobe23.3
Testis12.05
TestisGermCell10.95
TestisIntersitial13.25
TestisLeydigCell14.45
TestisSeminiferousTubule21.35
Thalamus26.95
Thymus15.35
Thyroid27.15
Tongue18.05
Tonsil27
Trachea13.35
TrigeminalGanglion23.55
Uterus10.05
UterusCorpus15
WholeBlood13.1
Wholebrain10.3
colon18.25
pineal_day18.7
pineal_night18.62
retina16.2
small_intestine13.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P414183
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.34 ± 0.53
Basal Forebrain6.88 ± 0.19
Basal Part of Pons7.81 ± 0.39
Cerebellar Cortex6.97 ± 0.22
Cerebellar Nuclei6.91 ± 0.42
Claustrum6.91 ± 0.55
Epithalamus7.3 ± 0.41
Frontal Lobe7.5 ± 0.42
Globus Pallidus6.63 ± 0.49
Hypothalamus7.13 ± 0.36
Insula7.74 ± 0.29
Limbic Lobe7.51 ± 0.39
Mesencephalon7.01 ± 0.33
Myelencephalon7.29 ± 0.46
Occipital Lobe6.92 ± 0.52
Parietal Lobe7.25 ± 0.45
Pontine Tegmentum7.18 ± 0.38
Striatum7.26 ± 0.51
Subthalamus7.09 ± 0.37
Temporal Lobe7.59 ± 0.4
Thalamus7.05 ± 0.45
White Matter6.69 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ogg1CBCerebellum1.01
1.97
Ogg1CTXCerebral cortex0.47
0.49
Ogg1HIPHippocampal region0.26
0.37
Ogg1HPFHippocampal formation0.23
0.26
Ogg1HYHypothalamus0.06
0.03
Ogg1LSXLateral septal complex0.03
0
Ogg1MBMidbrain0.28
0.4
Ogg1MYMedulla0.52
0.69
Ogg1OLFOlfactory bulb0.4
0.65
Ogg1PPons0.21
0.28
Ogg1PALPallidum0.08
0.1
Ogg1RHPRetrohippocampal region0.18
0.12
Ogg1sAMYStriatum-like amygdalar nuclei0.06
0.07
Ogg1STRStriatum0.1
0.12
Ogg1STRdStriatum dorsal region0.12
0.16
Ogg1STRvStriatum ventral region0.11
0.08
Ogg1THThalamus0.75
1.48
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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