AutismKB 2.0

Annotation Detail for OGN


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Basic Information Top
Gene Symbol:OGN ( DKFZp586P2421,OG,OIF,SLRR3A )
Gene Full Name: osteoglycin
Band: 9q22.31
Quick LinksEntrez ID:4969; OMIM: 602383; Uniprot ID:MIME_HUMAN; ENSEMBL ID: ENSG00000106809; HGNC ID: 8126
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus204 / 564012361
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult73 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor2 / 17290115
gastrointestinal tumor8 / 11936967
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor7 / 68959101
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal476 / 3360307141
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone4 / 7165555
bone marrow0 / 488010 
brain126 / 1100989114
cervix1 / 4817120
connective tissue15 / 149255100
ear95 / 162125859
embryonic tissue37 / 215722171
esophagus2 / 2020998
eye16 / 21105475
heart12 / 89626133
intestine14 / 23447259
kidney11 / 21177751
larynx4 / 24145165
liver2 / 2077439
lung11 / 33697432
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth7 / 67052104
muscle2 / 10771518
nerve4 / 15768253
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid8 / 20539389
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta6 / 28082521
prostate7 / 18934536
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach10 / 96619103
testis2 / 3304426
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea18 / 52413343
umbilical cord0 / 136800 
uterus93 / 232878399
vascular94 / 517801815
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218730_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.7
Adipocyte8
AdrenalCortex11.25
Adrenalgland7.4
Amygdala7.75
Appendix11.4
AtrioventricularNode13.2
BDCA4+_DentriticCells7.7
Bonemarrow9.4
BronchialEpithelialCells7.45
CD105+_Endothelial7.9
CD14+_Monocytes8.6
CD19+_BCells(neg._sel.)8
CD33+_Myeloid9.55
CD34+9.5
CD4+_Tcells8.05
CD56+_NKCells8.8
CD71+_EarlyErythroid7.55
CD8+_Tcells7
CardiacMyocytes11.7
Caudatenucleus7.05
Cerebellum6.5
CerebellumPeduncles10.25
CiliaryGanglion42.3
CingulateCortex8.5
Colorectaladenocarcinoma7.8
DorsalRootGanglion10.3
FetalThyroid8.45
Fetalbrain7.55
Fetalliver7.45
Fetallung9.7
GlobusPallidus6.85
Heart11.7
Hypothalamus8.15
Kidney7.85
Leukemia_chronicMyelogenousK-5627.05
Leukemia_promyelocytic-HL-606.95
Leukemialymphoblastic(MOLT-4)6.6
Liver11.2
Lung8.5
Lymphnode6.5
Lymphoma_burkitts(Daudi)10.8
Lymphoma_burkitts(Raji)12
MedullaOblongata7
OccipitalLobe7
OlfactoryBulb21.05
Ovary7.55
Pancreas7.05
PancreaticIslet8.45
ParietalLobe8.65
Pituitary15.55
Placenta7.75
Pons8.3
PrefrontalCortex9.2
Prostate8.95
Salivarygland7
SkeletalMuscle13.8
Skin8.8
SmoothMuscle8.9
Spinalcord11.8
SubthalamicNucleus8.1
SuperiorCervicalGanglion35.2
TemporalLobe7.7
Testis6.7
TestisGermCell7
TestisIntersitial7.55
TestisLeydigCell8.75
TestisSeminiferousTubule6.75
Thalamus8.2
Thymus5.85
Thyroid9.95
Tongue10.2
Tonsil8.1
Trachea14.6
TrigeminalGanglion17
Uterus212.3
UterusCorpus10.45
WholeBlood8.5
Wholebrain6.15
colon7.85
pineal_day9.64
pineal_night10.16
retina9.95
small_intestine7.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9254_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.16 ± 0.96
Basal Forebrain2.58 ± 0.69
Basal Part of Pons2.33 ± 0.67
Cerebellar Cortex2.97 ± 0.7
Cerebellar Nuclei4.07 ± 0.85
Claustrum2.94 ± 0.62
Epithalamus4.35 ± 0.52
Frontal Lobe2.86 ± 1.07
Globus Pallidus4.55 ± 0.79
Hypothalamus3.41 ± 1.26
Insula2.93 ± 0.94
Limbic Lobe2.73 ± 0.92
Mesencephalon3.22 ± 0.86
Myelencephalon3.11 ± 0.85
Occipital Lobe2.95 ± 0.82
Parietal Lobe2.64 ± 0.89
Pontine Tegmentum3.18 ± 0.95
Striatum4.08 ± 0.86
Subthalamus2.86 ± 0.4
Temporal Lobe2.83 ± 1.01
Thalamus3.1 ± 0.71
White Matter3.41 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
OgnCBCerebellum9.19
8.72
OgnCTXCerebral cortex8.26
6.1
OgnHIPHippocampal region8.9
5.64
OgnHPFHippocampal formation8.53
6.41
OgnHYHypothalamus3.73
2.43
OgnLSXLateral septal complex2.7
1.31
OgnMBMidbrain5.18
7.44
OgnMYMedulla3.33
2.86
OgnOLFOlfactory bulb22.84
13.85
OgnPPons3.98
5.67
OgnPALPallidum3.05
2.12
OgnRHPRetrohippocampal region7.99
7.12
OgnsAMYStriatum-like amygdalar nuclei1.93
1.05
OgnSTRStriatum2.82
1.82
OgnSTRdStriatum dorsal region1.63
0.98
OgnSTRvStriatum ventral region7.97
5.45
OgnTHThalamus3.06
2.39
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MIME_HUMAN_166 16 166 181 LSLLEELSLAENQLLK PRIDE
PAp00136230 8 291 298 RLPIGSYF Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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