AutismKB 2.0

Annotation Detail for OPCML


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Basic Information Top
Gene Symbol:OPCML ( IGLON1,OBCAM,OPCM )
Gene Full Name: opioid binding protein/cell adhesion molecule-like
Band: 11q25
Quick LinksEntrez ID:4978; OMIM: 600632; Uniprot ID:OPCM_HUMAN; ENSEMBL ID: ENSG00000183715; HGNC ID: 8143
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus29 / 56401251
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal134 / 336030739
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain101 / 110098991
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye8 / 21105437
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214111_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.1
Adipocyte8.35
AdrenalCortex14.75
Adrenalgland8.2
Amygdala816.9
Appendix19.3
AtrioventricularNode9.7
BDCA4+_DentriticCells7.35
Bonemarrow10.65
BronchialEpithelialCells8.3
CD105+_Endothelial9.65
CD14+_Monocytes10.2
CD19+_BCells(neg._sel.)9.3
CD33+_Myeloid10
CD34+11.65
CD4+_Tcells8.9
CD56+_NKCells9.3
CD71+_EarlyErythroid9.05
CD8+_Tcells8.25
CardiacMyocytes18.7
Caudatenucleus110.05
Cerebellum169.95
CerebellumPeduncles198.4
CiliaryGanglion9.05
CingulateCortex326.45
Colorectaladenocarcinoma9.75
DorsalRootGanglion14.85
FetalThyroid9.35
Fetalbrain1138.05
Fetalliver7.4
Fetallung6
GlobusPallidus154.15
Heart14.75
Hypothalamus360.3
Kidney8.15
Leukemia_chronicMyelogenousK-5627.5
Leukemia_promyelocytic-HL-607.65
Leukemialymphoblastic(MOLT-4)6.15
Liver15.6
Lung10.5
Lymphnode8.45
Lymphoma_burkitts(Daudi)12.45
Lymphoma_burkitts(Raji)15.4
MedullaOblongata324.1
OccipitalLobe367.5
OlfactoryBulb9.15
Ovary7.1
Pancreas7.9
PancreaticIslet10.3
ParietalLobe277.75
Pituitary14.2
Placenta9.55
Pons104
PrefrontalCortex876.55
Prostate9.7
Salivarygland18.15
SkeletalMuscle42.55
Skin11.1
SmoothMuscle9.55
Spinalcord30.35
SubthalamicNucleus249.1
SuperiorCervicalGanglion28.95
TemporalLobe214.8
Testis6.75
TestisGermCell8.6
TestisIntersitial8.25
TestisLeydigCell16.85
TestisSeminiferousTubule13.25
Thalamus321.1
Thymus6
Thyroid9.8
Tongue13.8
Tonsil9.25
Trachea6.65
TrigeminalGanglion47.05
Uterus6.45
UterusCorpus11.4
WholeBlood10
Wholebrain430.05
colon8.6
pineal_day31.86
pineal_night39.76
retina121.45
small_intestine8.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P72663
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.35 ± 0.52
Basal Forebrain8.03 ± 0.29
Basal Part of Pons7.17 ± 0.32
Cerebellar Cortex8.56 ± 0.23
Cerebellar Nuclei7.9 ± 0.56
Claustrum8.8 ± 0.48
Epithalamus6.67 ± 0.89
Frontal Lobe8.33 ± 0.47
Globus Pallidus6.43 ± 0.55
Hypothalamus7.43 ± 0.72
Insula8.33 ± 0.2
Limbic Lobe8.59 ± 0.6
Mesencephalon7.95 ± 0.63
Myelencephalon8.1 ± 0.75
Occipital Lobe8.01 ± 0.57
Parietal Lobe8.43 ± 0.48
Pontine Tegmentum8.3 ± 0.49
Striatum7.07 ± 0.67
Subthalamus8.08 ± 0.4
Temporal Lobe8.41 ± 0.33
Thalamus8.36 ± 0.47
White Matter5.92 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
OpcmlCBCerebellum21.2
33.22
OpcmlCTXCerebral cortex98.51
100
OpcmlHIPHippocampal region84.97
100
OpcmlHPFHippocampal formation90.25
100
OpcmlHYHypothalamus22.11
21.21
OpcmlLSXLateral septal complex46.28
40.4
OpcmlMBMidbrain32.08
34.03
OpcmlMYMedulla26.43
34.36
OpcmlOLFOlfactory bulb75.49
87.22
OpcmlPPons29.05
34.63
OpcmlPALPallidum21.78
23.14
OpcmlRHPRetrohippocampal region93.62
98.46
OpcmlsAMYStriatum-like amygdalar nuclei38.74
34.71
OpcmlSTRStriatum22.15
20.33
OpcmlSTRdStriatum dorsal region16.35
15.16
OpcmlSTRvStriatum ventral region22.36
20.5
OpcmlTHThalamus34
35.96
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00137377 11 218 228 ITVNYPPYISK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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