AutismKB 2.0

Annotation Detail for SLC22A18


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Basic Information Top
Gene Symbol:SLC22A18 ( BWR1A,BWSCR1A,DKFZp667A184,HET,IMPT1,ITM,ORCTL2,SLC22A1L,TSSC5,p45-BWR1A )
Gene Full Name: solute carrier family 22, member 18
Band: 11p15.4
Quick LinksEntrez ID:5002; OMIM: 602631; Uniprot ID:S22AI_HUMAN; ENSEMBL ID: ENSG00000110628; HGNC ID: 10964
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult39 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal38 / 336030711
ovarian tumor1 / 7668213
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor11 / 12494988
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain2 / 11009891
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye0 / 2110540 
heart1 / 8962611
intestine21 / 23447289
kidney5 / 21177723
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph1 / 4427022
lymph node0 / 916100 
mammary gland9 / 15327158
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary1 / 1020519
pancreas16 / 21481274
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin13 / 21057461
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204981_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.15
Adipocyte5.55
AdrenalCortex5
Adrenalgland4.05
Amygdala4.85
Appendix4.85
AtrioventricularNode3.65
BDCA4+_DentriticCells13.35
Bonemarrow4.8
BronchialEpithelialCells7.35
CD105+_Endothelial4.95
CD14+_Monocytes42.25
CD19+_BCells(neg._sel.)5.2
CD33+_Myeloid37.15
CD34+6.35
CD4+_Tcells7
CD56+_NKCells12.35
CD71+_EarlyErythroid5
CD8+_Tcells5
CardiacMyocytes6.35
Caudatenucleus4.3
Cerebellum3.85
CerebellumPeduncles5.45
CiliaryGanglion3.35
CingulateCortex4.95
Colorectaladenocarcinoma5.75
DorsalRootGanglion3.7
FetalThyroid10.35
Fetalbrain4.7
Fetalliver5.75
Fetallung4.7
GlobusPallidus3.5
Heart11.75
Hypothalamus5.2
Kidney133.7
Leukemia_chronicMyelogenousK-5624.3
Leukemia_promyelocytic-HL-604.15
Leukemialymphoblastic(MOLT-4)3.95
Liver299
Lung28.3
Lymphnode4.5
Lymphoma_burkitts(Daudi)5.95
Lymphoma_burkitts(Raji)7.2
MedullaOblongata4.35
OccipitalLobe4.3
OlfactoryBulb3.9
Ovary3.2
Pancreas25.35
PancreaticIslet5.2
ParietalLobe5.05
Pituitary5.75
Placenta5.2
Pons4.6
PrefrontalCortex5.8
Prostate24.25
Salivarygland5.65
SkeletalMuscle5.6
Skin3.65
SmoothMuscle5.45
Spinalcord5.1
SubthalamicNucleus4.9
SuperiorCervicalGanglion5.55
TemporalLobe4.4
Testis9.55
TestisGermCell6
TestisIntersitial7.75
TestisLeydigCell4.9
TestisSeminiferousTubule5.3
Thalamus5
Thymus3.9
Thyroid19.75
Tongue7.6
Tonsil4.75
Trachea5
TrigeminalGanglion4.7
Uterus3.9
UterusCorpus4.3
WholeBlood8.55
Wholebrain4.05
colon53.55
pineal_day5.8
pineal_night5.66
retina5.85
small_intestine14.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P127868
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.42 ± 0.81
Basal Forebrain2.45 ± 0.83
Basal Part of Pons1.84 ± 0.54
Cerebellar Cortex1.99 ± 0.59
Cerebellar Nuclei2.56 ± 0.53
Claustrum2.52 ± 0.7
Epithalamus1.74 ± 0.97
Frontal Lobe2.68 ± 0.65
Globus Pallidus2.27 ± 0.82
Hypothalamus2.41 ± 0.72
Insula1.98 ± 0.74
Limbic Lobe2.24 ± 0.62
Mesencephalon2.33 ± 0.71
Myelencephalon2.31 ± 0.68
Occipital Lobe1.59 ± 0.72
Parietal Lobe2.34 ± 0.63
Pontine Tegmentum2.38 ± 0.66
Striatum1.83 ± 0.81
Subthalamus2.24 ± 0.49
Temporal Lobe2.31 ± 0.61
Thalamus2.39 ± 0.62
White Matter1.95 ± 0.75
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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