Annotation Detail for OTX1
Basic Information Top
| Gene Symbol: | OTX1 ( FLJ38361,MGC15736 ) |
|---|---|
| Gene Full Name: | orthodenticle homeobox 1 |
| Band: | 2p15 |
| Quick Links | Entrez ID:5013; OMIM: 600036; Uniprot ID:OTX1_HUMAN; ENSEMBL ID: ENSG00000115507; HGNC ID: 8521 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.445340
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 6 / 564012 | 10 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 13 / 1939121 | 6 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 5 / 94178 | 53 |  |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 3 / 17290 | 173 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 4 / 263845 | 15 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 17 / 3360307 | 5 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 8 / 1100989 | 7 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 3 / 215722 | 13 | |
| esophagus | 3 / 20209 | 148 | |
| eye | 7 / 211054 | 33 | |
| heart | 0 / 89626 | 0 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 4 / 336974 | 11 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 1 / 214812 | 4 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_24_P359799
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.88 ± 1.06 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.45 ± 0.64 | |
| Basal Part of Pons | 2.32 ± 0.35 | |
| Cerebellar Cortex | 2.31 ± 0.65 | |
| Cerebellar Nuclei | 2.36 ± 0.62 | |
| Claustrum | 3.19 ± 0.82 | |
| Epithalamus | 4.04 ± 1.08 | |
| Frontal Lobe | 2.57 ± 0.76 | |
| Globus Pallidus | 3.37 ± 0.58 | |
| Hypothalamus | 2.72 ± 0.36 | |
| Insula | 2.44 ± 0.63 | |
| Limbic Lobe | 2.66 ± 0.75 | |
| Mesencephalon | 2.86 ± 0.69 | |
| Myelencephalon | 2.76 ± 0.71 | |
| Occipital Lobe | 3.05 ± 0.65 | |
| Parietal Lobe | 2.89 ± 0.75 | |
| Pontine Tegmentum | 2.78 ± 0.8 | |
| Striatum | 2.65 ± 0.87 | |
| Subthalamus | 2.07 ± 0.78 | |
| Temporal Lobe | 2.73 ± 0.76 | |
| Thalamus | 3.04 ± 0.52 | |
| White Matter | 2.24 ± 0.63 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Otx1 | CB | Cerebellum | 6.42 | |
| 6.38 | | |||
| Otx1 | CTX | Cerebral cortex | 1.83 | |
| 1.53 | | |||
| Otx1 | HIP | Hippocampal region | 7.48 | |
| 3.99 | | |||
| Otx1 | HPF | Hippocampal formation | 6.12 | |
| 3.48 | | |||
| Otx1 | HY | Hypothalamus | 0.79 | |
| 0.8 | | |||
| Otx1 | LSX | Lateral septal complex | 0.5 | |
| 0.32 | | |||
| Otx1 | MB | Midbrain | 1.5 | |
| 1.47 | | |||
| Otx1 | MY | Medulla | 3.34 | |
| 3.17 | | |||
| Otx1 | OLF | Olfactory bulb | 4.78 | |
| 3.55 | | |||
| Otx1 | P | Pons | 2.06 | |
| 1.98 | | |||
| Otx1 | PAL | Pallidum | 0.74 | |
| 0.66 | | |||
| Otx1 | RHP | Retrohippocampal region | 3.32 | |
| 2.58 | | |||
| Otx1 | sAMY | Striatum-like amygdalar nuclei | 0.39 | |
| 0.3 | | |||
| Otx1 | STR | Striatum | 0.62 | |
| 0.39 | | |||
| Otx1 | STRd | Striatum dorsal region | 0.25 | |
| 0.19 | | |||
| Otx1 | STRv | Striatum ventral region | 2.23 | |
| 1.17 | | |||
| Otx1 | TH | Thalamus | 1.47 | |
| 1.18 | |