AutismKB 2.0

Annotation Detail for OVOL1


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Basic Information Top
Gene Symbol:OVOL1 ( HOVO1 )
Gene Full Name: ovo-like 1(Drosophila)
Band: 11q13.1
Quick LinksEntrez ID:5017; OMIM: 602313; Uniprot ID:OVOL1_HUMAN; ENSEMBL ID: ENSG00000172818; HGNC ID: 8525
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus6 / 56401210
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal44 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye1 / 2110544
heart0 / 896260 
intestine5 / 23447221
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth5 / 6705274
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis22 / 33044266
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206604_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.8
Adipocyte4
AdrenalCortex4.15
Adrenalgland3.35
Amygdala4.3
Appendix4
AtrioventricularNode3.05
BDCA4+_DentriticCells4.25
Bonemarrow3.95
BronchialEpithelialCells4
CD105+_Endothelial4.05
CD14+_Monocytes4.2
CD19+_BCells(neg._sel.)4.25
CD33+_Myeloid5.05
CD34+4.9
CD4+_Tcells4.35
CD56+_NKCells4.75
CD71+_EarlyErythroid3.75
CD8+_Tcells3.85
CardiacMyocytes5
Caudatenucleus3.6
Cerebellum3.25
CerebellumPeduncles4.55
CiliaryGanglion2.85
CingulateCortex4.05
Colorectaladenocarcinoma4.05
DorsalRootGanglion3
FetalThyroid3.9
Fetalbrain4.05
Fetalliver3.4
Fetallung3.4
GlobusPallidus2.95
Heart5
Hypothalamus4.4
Kidney3.15
Leukemia_chronicMyelogenousK-5623.65
Leukemia_promyelocytic-HL-603.55
Leukemialymphoblastic(MOLT-4)3.25
Liver5.2
Lung4.4
Lymphnode3.65
Lymphoma_burkitts(Daudi)5.1
Lymphoma_burkitts(Raji)5.55
MedullaOblongata3.7
OccipitalLobe3.6
OlfactoryBulb3.2
Ovary2.6
Pancreas3.2
PancreaticIslet4.25
ParietalLobe4.15
Pituitary4.7
Placenta4.25
Pons3.85
PrefrontalCortex5
Prostate4.7
Salivarygland3.2
SkeletalMuscle4.75
Skin3
SmoothMuscle4.6
Spinalcord4.3
SubthalamicNucleus3.6
SuperiorCervicalGanglion4.85
TemporalLobe3.65
Testis7.85
TestisGermCell5.05
TestisIntersitial5.15
TestisLeydigCell7.65
TestisSeminiferousTubule4.65
Thalamus4.1
Thymus3.25
Thyroid5.1
Tongue3.85
Tonsil3.9
Trachea3.4
TrigeminalGanglion4.1
Uterus3.3
UterusCorpus3.55
WholeBlood4.4
Wholebrain3.45
colon4.05
pineal_day4.96
pineal_night4.86
retina4.825
small_intestine3.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P326700
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.36 ± 0.96
Basal Forebrain1.99 ± 0.22
Basal Part of Pons1.65 ± 0.34
Cerebellar Cortex1.77 ± 0.65
Cerebellar Nuclei2.26 ± 0.67
Claustrum2.79 ± 0.79
Epithalamus1.68 ± 0.73
Frontal Lobe1.78 ± 0.59
Globus Pallidus2.54 ± 0.31
Hypothalamus1.97 ± 0.61
Insula1.99 ± 0.73
Limbic Lobe1.95 ± 0.58
Mesencephalon2.1 ± 0.63
Myelencephalon1.96 ± 0.61
Occipital Lobe2.03 ± 0.53
Parietal Lobe1.95 ± 0.63
Pontine Tegmentum2.01 ± 0.66
Striatum2.16 ± 0.52
Subthalamus2.14 ± 0.68
Temporal Lobe1.82 ± 0.55
Thalamus1.92 ± 0.53
White Matter2.58 ± 0.44
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018