AutismKB 2.0

Annotation Detail for OXTR


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Basic Information Top
Gene Symbol:OXTR ( OT-R )
Gene Full Name: oxytocin receptor
Band: 3p25.3
Quick LinksEntrez ID:5021; OMIM: 167055; Uniprot ID:OXYR_HUMAN; ENSEMBL ID: ENSG00000180914; HGNC ID: 8529
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult14 / 19391217
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206825_at
Cell line Expression level Expression bar
721_B_lymphoblasts86.35
Adipocyte9.9
AdrenalCortex11.8
Adrenalgland9.3
Amygdala10
Appendix16.4
AtrioventricularNode22.15
BDCA4+_DentriticCells9.65
Bonemarrow12.6
BronchialEpithelialCells8.85
CD105+_Endothelial9.95
CD14+_Monocytes10.45
CD19+_BCells(neg._sel.)10.1
CD33+_Myeloid11.55
CD34+12.3
CD4+_Tcells9.8
CD56+_NKCells9.7
CD71+_EarlyErythroid9.5
CD8+_Tcells8.3
CardiacMyocytes17.1
Caudatenucleus9
Cerebellum8.25
CerebellumPeduncles12.25
CiliaryGanglion13.15
CingulateCortex12
Colorectaladenocarcinoma10.05
DorsalRootGanglion13.9
FetalThyroid9.8
Fetalbrain9.6
Fetalliver8.8
Fetallung7.1
GlobusPallidus8.25
Heart19
Hypothalamus12.15
Kidney10.15
Leukemia_chronicMyelogenousK-5629.05
Leukemia_promyelocytic-HL-608.6
Leukemialymphoblastic(MOLT-4)7.15
Liver16.35
Lung11.05
Lymphnode8.15
Lymphoma_burkitts(Daudi)13.4
Lymphoma_burkitts(Raji)15.25
MedullaOblongata8.95
OccipitalLobe8.7
OlfactoryBulb8.2
Ovary9.6
Pancreas8.3
PancreaticIslet12.45
ParietalLobe11.2
Pituitary11.45
Placenta10.1
Pons11.05
PrefrontalCortex12.55
Prostate12
Salivarygland8.9
SkeletalMuscle15.4
Skin11.7
SmoothMuscle11.2
Spinalcord12.9
SubthalamicNucleus19.75
SuperiorCervicalGanglion23.85
TemporalLobe9.4
Testis8.45
TestisGermCell8
TestisIntersitial8.55
TestisLeydigCell12.4
TestisSeminiferousTubule8.85
Thalamus10.5
Thymus7.65
Thyroid12.2
Tongue11.6
Tonsil9.95
Trachea8.65
TrigeminalGanglion14.4
Uterus7.65
UterusCorpus10.45
WholeBlood10.8
Wholebrain8.2
colon10.15
pineal_day12.18
pineal_night11.62
retina12.25
small_intestine8.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P337104
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.54 ± 0.91
Basal Forebrain2.35 ± 0.45
Basal Part of Pons2.23 ± 0.54
Cerebellar Cortex2.01 ± 0.55
Cerebellar Nuclei2.45 ± 0.7
Claustrum2.74 ± 0.61
Epithalamus1.91 ± 0.78
Frontal Lobe2.26 ± 0.78
Globus Pallidus3.27 ± 0.76
Hypothalamus2.6 ± 1.14
Insula2.5 ± 0.6
Limbic Lobe2.36 ± 0.73
Mesencephalon2.63 ± 0.76
Myelencephalon2.37 ± 0.73
Occipital Lobe2.27 ± 0.69
Parietal Lobe2.21 ± 0.7
Pontine Tegmentum2.19 ± 0.74
Striatum2.57 ± 0.71
Subthalamus2.41 ± 0.75
Temporal Lobe2.23 ± 0.69
Thalamus2.32 ± 0.65
White Matter2.55 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
OxtrCBCerebellum1.65
2.22
OxtrCTXCerebral cortex6.05
3.05
OxtrHIPHippocampal region1.73
1.49
OxtrHPFHippocampal formation3.8
1.79
OxtrHYHypothalamus1.71
0.88
OxtrLSXLateral septal complex1.4
0.81
OxtrMBMidbrain1.39
1.46
OxtrMYMedulla3.43
2.48
OxtrOLFOlfactory bulb13.23
5.19
OxtrPPons1.49
0.99
OxtrPALPallidum0.4
0.3
OxtrRHPRetrohippocampal region6.28
2.14
OxtrsAMYStriatum-like amygdalar nuclei12.79
5.72
OxtrSTRStriatum2.63
1.41
OxtrSTRdStriatum dorsal region1.54
0.73
OxtrSTRvStriatum ventral region1.66
1.98
OxtrTHThalamus2.05
0.89
Peptide Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018