AutismKB 2.0

Annotation Detail for OXTR


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Basic Information Top
Gene Symbol:OXTR ( OT-R )
Gene Full Name: oxytocin receptor
Band: 3p25.3
Quick LinksEntrez ID:5021; OMIM: 167055; Uniprot ID:OXYR_HUMAN; ENSEMBL ID: ENSG00000180914; HGNC ID: 8529
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult14 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal66 / 336030719
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain20 / 110098918
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine0 / 2344720 
kidney23 / 211777108
larynx0 / 241450 
liver5 / 20774324
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin27 / 210574128
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206825_at
Cell line Expression level Expression bar
721_B_lymphoblasts86.35
Adipocyte9.9
AdrenalCortex11.8
Adrenalgland9.3
Amygdala10
Appendix16.4
AtrioventricularNode22.15
BDCA4+_DentriticCells9.65
Bonemarrow12.6
BronchialEpithelialCells8.85
CD105+_Endothelial9.95
CD14+_Monocytes10.45
CD19+_BCells(neg._sel.)10.1
CD33+_Myeloid11.55
CD34+12.3
CD4+_Tcells9.8
CD56+_NKCells9.7
CD71+_EarlyErythroid9.5
CD8+_Tcells8.3
CardiacMyocytes17.1
Caudatenucleus9
Cerebellum8.25
CerebellumPeduncles12.25
CiliaryGanglion13.15
CingulateCortex12
Colorectaladenocarcinoma10.05
DorsalRootGanglion13.9
FetalThyroid9.8
Fetalbrain9.6
Fetalliver8.8
Fetallung7.1
GlobusPallidus8.25
Heart19
Hypothalamus12.15
Kidney10.15
Leukemia_chronicMyelogenousK-5629.05
Leukemia_promyelocytic-HL-608.6
Leukemialymphoblastic(MOLT-4)7.15
Liver16.35
Lung11.05
Lymphnode8.15
Lymphoma_burkitts(Daudi)13.4
Lymphoma_burkitts(Raji)15.25
MedullaOblongata8.95
OccipitalLobe8.7
OlfactoryBulb8.2
Ovary9.6
Pancreas8.3
PancreaticIslet12.45
ParietalLobe11.2
Pituitary11.45
Placenta10.1
Pons11.05
PrefrontalCortex12.55
Prostate12
Salivarygland8.9
SkeletalMuscle15.4
Skin11.7
SmoothMuscle11.2
Spinalcord12.9
SubthalamicNucleus19.75
SuperiorCervicalGanglion23.85
TemporalLobe9.4
Testis8.45
TestisGermCell8
TestisIntersitial8.55
TestisLeydigCell12.4
TestisSeminiferousTubule8.85
Thalamus10.5
Thymus7.65
Thyroid12.2
Tongue11.6
Tonsil9.95
Trachea8.65
TrigeminalGanglion14.4
Uterus7.65
UterusCorpus10.45
WholeBlood10.8
Wholebrain8.2
colon10.15
pineal_day12.18
pineal_night11.62
retina12.25
small_intestine8.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P337104
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.54 ± 0.91
Basal Forebrain2.35 ± 0.45
Basal Part of Pons2.23 ± 0.54
Cerebellar Cortex2.01 ± 0.55
Cerebellar Nuclei2.45 ± 0.7
Claustrum2.74 ± 0.61
Epithalamus1.91 ± 0.78
Frontal Lobe2.26 ± 0.78
Globus Pallidus3.27 ± 0.76
Hypothalamus2.6 ± 1.14
Insula2.5 ± 0.6
Limbic Lobe2.36 ± 0.73
Mesencephalon2.63 ± 0.76
Myelencephalon2.37 ± 0.73
Occipital Lobe2.27 ± 0.69
Parietal Lobe2.21 ± 0.7
Pontine Tegmentum2.19 ± 0.74
Striatum2.57 ± 0.71
Subthalamus2.41 ± 0.75
Temporal Lobe2.23 ± 0.69
Thalamus2.32 ± 0.65
White Matter2.55 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
OxtrCBCerebellum1.65
2.22
OxtrCTXCerebral cortex6.05
3.05
OxtrHIPHippocampal region1.73
1.49
OxtrHPFHippocampal formation3.8
1.79
OxtrHYHypothalamus1.71
0.88
OxtrLSXLateral septal complex1.4
0.81
OxtrMBMidbrain1.39
1.46
OxtrMYMedulla3.43
2.48
OxtrOLFOlfactory bulb13.23
5.19
OxtrPPons1.49
0.99
OxtrPALPallidum0.4
0.3
OxtrRHPRetrohippocampal region6.28
2.14
OxtrsAMYStriatum-like amygdalar nuclei12.79
5.72
OxtrSTRStriatum2.63
1.41
OxtrSTRdStriatum dorsal region1.54
0.73
OxtrSTRvStriatum ventral region1.66
1.98
OxtrTHThalamus2.05
0.89
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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