AutismKB 2.0

Annotation Detail for P2RX5


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Basic Information Top
Gene Symbol:P2RX5 ( LRH-1,MGC47755,P2X5,P2X5R )
Gene Full Name: purinergic receptor P2X, ligand-gated ion channel, 5
Band: 17p13.2
Quick LinksEntrez ID:5026; OMIM: 602836; Uniprot ID:P2RX5_HUMAN; ENSEMBL ID: ENSG00000083454; HGNC ID: 8536
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult30 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia7 / 9584273
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma8 / 71755111
non-neoplasia0 / 972500 
normal54 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood8 / 12347864
bone1 / 7165513
bone marrow2 / 4880140
brain16 / 110098914
cervix9 / 48171186
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine6 / 23447225
kidney4 / 21177718
larynx1 / 2414541
liver0 / 2077430 
lung5 / 33697414
lymph4 / 4427090
lymph node6 / 9161065
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen7 / 53952129
stomach0 / 966190 
testis0 / 3304420 
thymus2 / 8113124
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210448_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts187.5
Adipocyte3.75
AdrenalCortex3.85
Adrenalgland3.2
Amygdala5.3
Appendix3.8
AtrioventricularNode2.8
BDCA4+_DentriticCells136.1
Bonemarrow4.55
BronchialEpithelialCells3.75
CD105+_Endothelial4.5
CD14+_Monocytes4.3
CD19+_BCells(neg._sel.)1919.95
CD33+_Myeloid4.8
CD34+105.7
CD4+_Tcells52.6
CD56+_NKCells33.55
CD71+_EarlyErythroid3.55
CD8+_Tcells34.15
CardiacMyocytes4.95
Caudatenucleus3.5
Cerebellum3.1
CerebellumPeduncles4.3
CiliaryGanglion2.6
CingulateCortex3.95
Colorectaladenocarcinoma7.75
DorsalRootGanglion2.85
FetalThyroid3.65
Fetalbrain6.25
Fetalliver3.25
Fetallung3.7
GlobusPallidus2.85
Heart9.5
Hypothalamus4.75
Kidney3.05
Leukemia_chronicMyelogenousK-5623.65
Leukemia_promyelocytic-HL-60875.5
Leukemialymphoblastic(MOLT-4)29.7
Liver4.95
Lung4.35
Lymphnode164.7
Lymphoma_burkitts(Daudi)84.25
Lymphoma_burkitts(Raji)2263.3
MedullaOblongata4.15
OccipitalLobe4.1
OlfactoryBulb3.05
Ovary2.5
Pancreas3.5
PancreaticIslet4.1
ParietalLobe4
Pituitary4.35
Placenta3.8
Pons4.6
PrefrontalCortex4.95
Prostate7.35
Salivarygland7.4
SkeletalMuscle4.75
Skin2.85
SmoothMuscle4.4
Spinalcord4.05
SubthalamicNucleus3.45
SuperiorCervicalGanglion4.25
TemporalLobe5.15
Testis3.3
TestisGermCell3.25
TestisIntersitial3.15
TestisLeydigCell3.75
TestisSeminiferousTubule3.3
Thalamus3.9
Thymus21.9
Thyroid4.75
Tongue3.7
Tonsil193.3
Trachea3.2
TrigeminalGanglion3.75
Uterus3.1
UterusCorpus3.4
WholeBlood10.4
Wholebrain13.05
colon3.8
pineal_day4.7
pineal_night4.62
retina4.625
small_intestine3.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P413760
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.51 ± 0.49
Basal Forebrain5.14 ± 0.5
Basal Part of Pons5.27 ± 0.55
Cerebellar Cortex4.83 ± 0.39
Cerebellar Nuclei4.67 ± 0.55
Claustrum6.01 ± 0.51
Epithalamus4.24 ± 0.65
Frontal Lobe5.34 ± 0.54
Globus Pallidus4.12 ± 0.89
Hypothalamus4.51 ± 0.49
Insula5.29 ± 0.24
Limbic Lobe5.58 ± 0.49
Mesencephalon5.19 ± 0.57
Myelencephalon5.22 ± 0.65
Occipital Lobe4.89 ± 0.63
Parietal Lobe5.27 ± 0.76
Pontine Tegmentum5.17 ± 0.77
Striatum5.48 ± 0.52
Subthalamus4.84 ± 0.26
Temporal Lobe5.41 ± 0.46
Thalamus5.27 ± 0.55
White Matter3.08 ± 0.74
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
P2rx5CBCerebellum3.7
4.28
P2rx5CTXCerebral cortex3.49
2.51
P2rx5HIPHippocampal region4.21
4.29
P2rx5HPFHippocampal formation3.8
3.12
P2rx5HYHypothalamus2.84
1.96
P2rx5LSXLateral septal complex2.99
2.06
P2rx5MBMidbrain5.76
5.21
P2rx5MYMedulla14.7
14.56
P2rx5OLFOlfactory bulb4.45
2.91
P2rx5PPons13.32
13.8
P2rx5PALPallidum2.65
2.03
P2rx5RHPRetrohippocampal region2.84
1.48
P2rx5sAMYStriatum-like amygdalar nuclei1.05
0.8
P2rx5STRStriatum1.17
0.74
P2rx5STRdStriatum dorsal region0.98
0.57
P2rx5STRvStriatum ventral region1.24
0.82
P2rx5THThalamus3.71
3.73
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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