Annotation Detail for P2RX7
Basic Information Top
| Gene Symbol: | P2RX7 ( MGC20089,P2X7 ) |
|---|---|
| Gene Full Name: | purinergic receptor P2X, ligand-gated ion channel, 7 |
| Band: | 12q24.31 |
| Quick Links | Entrez ID:5027; OMIM: 602566; Uniprot ID:A8K2Z0_HUMAN; ENSEMBL ID: ENSG00000089041; HGNC ID: 8537 |
| Relate to Another Database: | SFARIGene; denovo-db |
Unigene EST- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 207091_at
| Cell line | Expression level | Expression bar |
|---|---|---|
 | ||
| 721_B_lymphoblasts | 5.8 |  |
| Adipocyte | 4.9 | |
| AdrenalCortex | 5.1 | |
| Adrenalgland | 4.1 | |
| Amygdala | 6.4 | |
| Appendix | 4.85 | |
| AtrioventricularNode | 3.75 | |
| BDCA4+_DentriticCells | 7.1 | |
| Bonemarrow | 4.8 | |
| BronchialEpithelialCells | 7.6 | |
| CD105+_Endothelial | 4.8 | |
| CD14+_Monocytes | 10.65 |  |
| CD19+_BCells(neg._sel.) | 5.1 | |
| CD33+_Myeloid | 8.75 | |
| CD34+ | 6.1 | |
| CD4+_Tcells | 5.25 | |
| CD56+_NKCells | 5.7 | |
| CD71+_EarlyErythroid | 4.55 | |
| CD8+_Tcells | 5.15 | |
| CardiacMyocytes | 6.3 | |
| Caudatenucleus | 4.4 | |
| Cerebellum | 3.9 | |
| CerebellumPeduncles | 5.5 | |
| CiliaryGanglion | 3.45 | |
| CingulateCortex | 4.95 | |
| Colorectaladenocarcinoma | 4.85 | |
| DorsalRootGanglion | 3.75 | |
| FetalThyroid | 4.7 | |
| Fetalbrain | 4.8 | |
| Fetalliver | 4.2 | |
| Fetallung | 3.9 | |
| GlobusPallidus | 3.95 | |
| Heart | 6.7 | |
| Hypothalamus | 8.1 | |
| Kidney | 3.95 | |
| Leukemia_chronicMyelogenousK-562 | 4.35 | |
| Leukemia_promyelocytic-HL-60 | 4.25 | |
| Leukemialymphoblastic(MOLT-4) | 3.85 | |
| Liver | 17.8 | |
| Lung | 7.35 | |
| Lymphnode | 4.1 | |
| Lymphoma_burkitts(Daudi) | 6.2 | |
| Lymphoma_burkitts(Raji) | 6.8 | |
| MedullaOblongata | 4.7 | |
| OccipitalLobe | 7.95 | |
| OlfactoryBulb | 5.2 | |
| Ovary | 3.3 | |
| Pancreas | 3.9 | |
| PancreaticIslet | 5.15 | |
| ParietalLobe | 5.15 | |
| Pituitary | 5.6 | |
| Placenta | 4.9 | |
| Pons | 4.6 | |
| PrefrontalCortex | 19.75 | |
| Prostate | 7.95 | |
| Salivarygland | 3.9 | |
| SkeletalMuscle | 5.65 | |
| Skin | 3.75 | |
| SmoothMuscle | 5.45 | |
| Spinalcord | 5.55 | |
| SubthalamicNucleus | 4.4 | |
| SuperiorCervicalGanglion | 5.45 | |
| TemporalLobe | 4.4 | |
| Testis | 6.5 | |
| TestisGermCell | 3.95 | |
| TestisIntersitial | 4.15 | |
| TestisLeydigCell | 4.75 | |
| TestisSeminiferousTubule | 4.15 | |
| Thalamus | 5.85 | |
| Thymus | 3.8 | |
| Thyroid | 6 | |
| Tongue | 4.75 | |
| Tonsil | 4.7 | |
| Trachea | 4.05 | |
| TrigeminalGanglion | 4.85 | |
| Uterus | 3.9 | |
| UterusCorpus | 5.55 | |
| WholeBlood | 5.5 | |
| Wholebrain | 12.1 | |
| colon | 4.9 | |
| pineal_day | 6 | |
| pineal_night | 5.8 | |
| retina | 6.15 | |
| small_intestine | 4.65 | |
- Probe name: A_24_P319113
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.24 ± 0.86 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.36 ± 0.72 | |
| Basal Part of Pons | 4.55 ± 0.67 | |
| Cerebellar Cortex | 4.26 ± 0.37 | |
| Cerebellar Nuclei | 5.17 ± 0.56 | |
| Claustrum | 4.61 ± 0.76 | |
| Epithalamus | 4.42 ± 0.75 | |
| Frontal Lobe | 4.53 ± 0.74 | |
| Globus Pallidus | 6.03 ± 0.31 | |
| Hypothalamus | 4.04 ± 0.6 | |
| Insula | 4.43 ± 0.58 | |
| Limbic Lobe | 4.4 ± 0.62 | |
| Mesencephalon | 4.56 ± 0.8 | |
| Myelencephalon | 4.6 ± 0.75 | |
| Occipital Lobe | 4.86 ± 0.43 | |
| Parietal Lobe | 4.53 ± 0.67 | |
| Pontine Tegmentum | 4.73 ± 0.68 | |
| Striatum | 4.33 ± 0.78 | |
| Subthalamus | 4.91 ± 0.44 | |
| Temporal Lobe | 4.54 ± 0.58 | |
| Thalamus | 4.8 ± 0.58 | |
| White Matter | 7.16 ± 0.38 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| P2rx7 | CB | Cerebellum | 3.12 |  |
| 3.94 | | |||
| P2rx7 | CTX | Cerebral cortex | 1.75 | |
| 1.31 | | |||
| P2rx7 | HIP | Hippocampal region | 4.43 | |
| 3.08 | | |||
| P2rx7 | HPF | Hippocampal formation | 3.43 | |
| 3.01 | | |||
| P2rx7 | HY | Hypothalamus | 1.74 | |
| 1.91 | | |||
| P2rx7 | LSX | Lateral septal complex | 0.95 | |
| 0.78 | | |||
| P2rx7 | MB | Midbrain | 0.85 | |
| 0.93 | | |||
| P2rx7 | MY | Medulla | 1.61 | |
| 1.66 | | |||
| P2rx7 | OLF | Olfactory bulb | 1.74 | |
| 1.23 | | |||
| P2rx7 | P | Pons | 2.39 | |
| 2.83 | | |||
| P2rx7 | PAL | Pallidum | 0.73 | |
| 0.79 | | |||
| P2rx7 | RHP | Retrohippocampal region | 1.02 | |
| 0.97 | | |||
| P2rx7 | sAMY | Striatum-like amygdalar nuclei | 1.19 | |
| 0.9 | | |||
| P2rx7 | STR | Striatum | 0.52 | |
| 0.36 | | |||
| P2rx7 | STRd | Striatum dorsal region | 0.61 | |
| 0.57 | | |||
| P2rx7 | STRv | Striatum ventral region | 0.56 | |
| 0.27 | | |||
| P2rx7 | TH | Thalamus | 1.34 | |
| 1.08 | |