AutismKB 2.0

Annotation Detail for P2RY1


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Basic Information Top
Gene Symbol:P2RY1 ( P2Y1 )
Gene Full Name: purinergic receptor P2Y, G-protein coupled, 1
Band: 3q25.2
Quick LinksEntrez ID:5028; OMIM: 601167; Uniprot ID:P2RY1_HUMAN; ENSEMBL ID: ENSG00000169860; HGNC ID: 8539
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor9 / 13630266
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal17 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus1 / 2020949
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth10 / 67052149
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207455_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.35
Adipocyte5.6
AdrenalCortex6.5
Adrenalgland4.9
Amygdala5.75
Appendix6.4
AtrioventricularNode4.9
BDCA4+_DentriticCells5.5
Bonemarrow6
BronchialEpithelialCells5.55
CD105+_Endothelial5.6
CD14+_Monocytes5.9
CD19+_BCells(neg._sel.)5.6
CD33+_Myeloid6.9
CD34+6.65
CD4+_Tcells5.7
CD56+_NKCells6.25
CD71+_EarlyErythroid5.55
CD8+_Tcells5.05
CardiacMyocytes8.8
Caudatenucleus5.1
Cerebellum4.65
CerebellumPeduncles6.95
CiliaryGanglion4.4
CingulateCortex5.9
Colorectaladenocarcinoma5.65
DorsalRootGanglion5.1
FetalThyroid5.6
Fetalbrain5.55
Fetalliver5.05
Fetallung4.6
GlobusPallidus4.5
Heart8.25
Hypothalamus6.05
Kidney4.95
Leukemia_chronicMyelogenousK-5625.05
Leukemia_promyelocytic-HL-605
Leukemialymphoblastic(MOLT-4)4.45
Liver8.15
Lung6.15
Lymphnode4.85
Lymphoma_burkitts(Daudi)7.3
Lymphoma_burkitts(Raji)8.4
MedullaOblongata5.1
OccipitalLobe5.05
OlfactoryBulb4.5
Ovary4.05
Pancreas4.95
PancreaticIslet6.1
ParietalLobe6.6
Pituitary6.6
Placenta5.6
Pons5.45
PrefrontalCortex6.75
Prostate6.55
Salivarygland4.7
SkeletalMuscle8.6
Skin5.45
SmoothMuscle6.85
Spinalcord6.05
SubthalamicNucleus5.55
SuperiorCervicalGanglion7.95
TemporalLobe5.25
Testis4.85
TestisGermCell4.4
TestisIntersitial4.75
TestisLeydigCell5.7
TestisSeminiferousTubule5.4
Thalamus5.8
Thymus4.4
Thyroid6.85
Tongue5.85
Tonsil5.6
Trachea4.7
TrigeminalGanglion6.25
Uterus4.55
UterusCorpus5.5
WholeBlood6.15
Wholebrain4.55
colon5.7
pineal_day6.84
pineal_night6.68
retina6.825
small_intestine5.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10954_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.67 ± 0.57
Basal Forebrain5.22 ± 0.42
Basal Part of Pons3.66 ± 0.53
Cerebellar Cortex3.65 ± 0.29
Cerebellar Nuclei3.65 ± 0.81
Claustrum3.65 ± 1.06
Epithalamus5.26 ± 0.99
Frontal Lobe4.27 ± 0.63
Globus Pallidus5.55 ± 0.6
Hypothalamus4.43 ± 0.75
Insula4.21 ± 0.74
Limbic Lobe4.2 ± 0.77
Mesencephalon4.41 ± 0.67
Myelencephalon4.36 ± 0.82
Occipital Lobe4.68 ± 0.57
Parietal Lobe4.35 ± 0.71
Pontine Tegmentum4.57 ± 0.86
Striatum5.85 ± 0.6
Subthalamus3.54 ± 0.71
Temporal Lobe4.09 ± 0.53
Thalamus4.48 ± 0.6
White Matter3.41 ± 0.11
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018