AutismKB 2.0

Annotation Detail for MINK1


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Basic Information Top
Gene Symbol:MINK1 ( B55,MAP4K6,MGC21111,MINK,YSK2,ZC3,hMINK,hMINKbeta )
Gene Full Name: misshapen-like kinase 1
Band: 17p13.2
Quick LinksEntrez ID:50488; OMIM: 609426; Uniprot ID:MINK1_HUMAN; ENSEMBL ID: ENSG00000141503; HGNC ID: 17565
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus18 / 56401231
neonate0 / 310970 
infant2 / 2362084
juvenile2 / 5555635
adult140 / 193912172
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor6 / 9417863
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor9 / 26384534
glioma7 / 10688365
head and neck tumor8 / 13630258
kidney tumor7 / 68959101
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor11 / 103127106
lymphoma3 / 7175541
non-neoplasia7 / 9725071
normal165 / 336030749
ovarian tumor9 / 76682117
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer9 / 10268087
retinoblastoma3 / 4635664
skin tumor3 / 12494924
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites4 / 4001599
bladder3 / 29757100
blood4 / 12347832
bone2 / 7165527
bone marrow0 / 488010 
brain46 / 110098941
cervix1 / 4817120
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye27 / 211054127
heart1 / 8962611
intestine17 / 23447272
kidney12 / 21177756
larynx2 / 2414582
liver5 / 20774324
lung22 / 33697465
lymph3 / 4427067
lymph node1 / 9161010
mammary gland7 / 15327145
mouth3 / 6705244
muscle2 / 10771518
nerve2 / 15768126
ovary10 / 10205197
pancreas14 / 21481265
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta21 / 28082574
prostate12 / 18934563
salivary gland1 / 2015549
skin9 / 21057442
spleen3 / 5395255
stomach3 / 9661931
testis7 / 33044221
thymus4 / 8113149
thyroid3 / 4747363
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214625_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.2
Adipocyte3.25
AdrenalCortex3.4
Adrenalgland2.75
Amygdala3.5
Appendix3.3
AtrioventricularNode2.5
BDCA4+_DentriticCells3.7
Bonemarrow3.35
BronchialEpithelialCells3.25
CD105+_Endothelial3.35
CD14+_Monocytes3.5
CD19+_BCells(neg._sel.)3.5
CD33+_Myeloid4.3
CD34+4.25
CD4+_Tcells3.6
CD56+_NKCells3.95
CD71+_EarlyErythroid4.8
CD8+_Tcells3.2
CardiacMyocytes4.15
Caudatenucleus2.95
Cerebellum2.7
CerebellumPeduncles3.7
CiliaryGanglion2.3
CingulateCortex3.35
Colorectaladenocarcinoma3.3
DorsalRootGanglion2.55
FetalThyroid3.2
Fetalbrain3.3
Fetalliver2.85
Fetallung2.8
GlobusPallidus2.4
Heart4.45
Hypothalamus3.6
Kidney2.65
Leukemia_chronicMyelogenousK-5623
Leukemia_promyelocytic-HL-602.9
Leukemialymphoblastic(MOLT-4)2.65
Liver4.45
Lung3.7
Lymphnode2.85
Lymphoma_burkitts(Daudi)4.2
Lymphoma_burkitts(Raji)4.6
MedullaOblongata3.05
OccipitalLobe3
OlfactoryBulb2.6
Ovary2.2
Pancreas2.65
PancreaticIslet3.55
ParietalLobe3.45
Pituitary3.9
Placenta3.45
Pons3.15
PrefrontalCortex4.35
Prostate3.85
Salivarygland2.6
SkeletalMuscle3.7
Skin2.5
SmoothMuscle3.75
Spinalcord3.55
SubthalamicNucleus2.95
SuperiorCervicalGanglion3.75
TemporalLobe3.15
Testis2.85
TestisGermCell2.8
TestisIntersitial2.75
TestisLeydigCell3.25
TestisSeminiferousTubule2.8
Thalamus3.35
Thymus2.65
Thyroid4.2
Tongue3.2
Tonsil3.25
Trachea2.8
TrigeminalGanglion3.2
Uterus2.75
UterusCorpus2.95
WholeBlood3.65
Wholebrain3
colon3.35
pineal_day4.14
pineal_night4.04
retina4
small_intestine3.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P164313
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.98 ± 0.52
Basal Forebrain5.56 ± 0.25
Basal Part of Pons5.72 ± 0.35
Cerebellar Cortex5.33 ± 0.26
Cerebellar Nuclei5.26 ± 0.45
Claustrum5.75 ± 0.5
Epithalamus5.42 ± 0.38
Frontal Lobe5.59 ± 0.4
Globus Pallidus5.69 ± 0.26
Hypothalamus5.02 ± 0.45
Insula5.78 ± 0.3
Limbic Lobe6.03 ± 0.39
Mesencephalon5.44 ± 0.39
Myelencephalon5.71 ± 0.41
Occipital Lobe5.67 ± 0.31
Parietal Lobe5.57 ± 0.39
Pontine Tegmentum5.63 ± 0.46
Striatum6.09 ± 0.38
Subthalamus5.66 ± 0.19
Temporal Lobe5.77 ± 0.41
Thalamus5.65 ± 0.34
White Matter5.96 ± 0.32
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00428389 10 1065 1074 ILHNDPEVEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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