Annotation Detail for ITSN2
Basic Information Top
| Gene Symbol: | ITSN2 ( KIAA1256,PRO2015,SH3D1B,SH3P18,SWA,SWAP ) |
|---|---|
| Gene Full Name: | intersectin 2 |
| Band: | 2p23.3 |
| Quick Links | Entrez ID:50618; OMIM: 604464; Uniprot ID:ITSN2_HUMAN; ENSEMBL ID: ENSG00000198399; HGNC ID: 6184 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.432562
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 37 / 564012 | 65 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 92 / 1939121 | 47 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 7 / 119369 | 58 | |
| germ cell tumor | 10 / 263845 | 37 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 11 / 136302 | 80 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 6 / 71755 | 83 | |
| non-neoplasia | 6 / 97250 | 61 | |
| normal | 181 / 3360307 | 53 | |
| ovarian tumor | 5 / 76682 | 65 | |
| pancreatic tumor | 1 / 104616 | 9 |  |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 3 / 102680 | 29 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 4 / 124949 | 32 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 7 / 90257 | 77 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 3 / 33197 | 90 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 2 / 29757 | 67 | |
| blood | 3 / 123478 | 24 | |
| bone | 5 / 71655 | 69 | |
| bone marrow | 3 / 48801 | 61 | |
| brain | 20 / 1100989 | 18 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 6 / 149255 | 40 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 11 / 215722 | 50 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 6 / 211054 | 28 | |
| heart | 3 / 89626 | 33 | |
| intestine | 8 / 234472 | 34 | |
| kidney | 7 / 211777 | 33 | |
| larynx | 1 / 24145 | 41 | |
| liver | 9 / 207743 | 43 | |
| lung | 13 / 336974 | 38 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 29 / 91610 | 316 |  |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 4 / 67052 | 59 | |
| muscle | 6 / 107715 | 55 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 6 / 102051 | 58 | |
| pancreas | 7 / 214812 | 32 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 8 / 280825 | 28 | |
| prostate | 9 / 189345 | 47 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 21 / 210574 | 99 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 8 / 96619 | 82 | |
| testis | 2 / 330442 | 6 | |
| thymus | 5 / 81131 | 61 | |
| thyroid | 7 / 47473 | 147 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 12 / 232878 | 51 | |
| vascular | 2 / 51780 | 38 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 209907_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 14.55 | |
| Adipocyte | 4 | |
| AdrenalCortex | 4.25 | |
| Adrenalgland | 3.5 | |
| Amygdala | 4.35 | |
| Appendix | 8 | |
| AtrioventricularNode | 3.1 | |
| BDCA4+_DentriticCells | 25.25 | |
| Bonemarrow | 4.1 | |
| BronchialEpithelialCells | 3.95 | |
| CD105+_Endothelial | 4.55 | |
| CD14+_Monocytes | 17.8 | |
| CD19+_BCells(neg._sel.) | 66.75 | |
| CD33+_Myeloid | 87.8 | |
| CD34+ | 26.05 | |
| CD4+_Tcells | 40.55 | |
| CD56+_NKCells | 30.95 | |
| CD71+_EarlyErythroid | 3.6 | |
| CD8+_Tcells | 40.35 | |
| CardiacMyocytes | 5 | |
| Caudatenucleus | 3.75 | |
| Cerebellum | 3.35 | |
| CerebellumPeduncles | 4.7 | |
| CiliaryGanglion | 2.85 | |
| CingulateCortex | 4.25 | |
| Colorectaladenocarcinoma | 4.25 | |
| DorsalRootGanglion | 3.1 | |
| FetalThyroid | 19.55 | |
| Fetalbrain | 4.25 | |
| Fetalliver | 3.6 | |
| Fetallung | 4.5 | |
| GlobusPallidus | 3 | |
| Heart | 5.2 | |
| Hypothalamus | 4.65 | |
| Kidney | 3.35 | |
| Leukemia_chronicMyelogenousK-562 | 3.8 | |
| Leukemia_promyelocytic-HL-60 | 4.6 | |
| Leukemialymphoblastic(MOLT-4) | 3.35 | |
| Liver | 5.35 | |
| Lung | 4.65 | |
| Lymphnode | 8.5 | |
| Lymphoma_burkitts(Daudi) | 8.45 | |
| Lymphoma_burkitts(Raji) | 5.8 | |
| MedullaOblongata | 3.95 | |
| OccipitalLobe | 3.8 | |
| OlfactoryBulb | 3.35 | |
| Ovary | 2.75 | |
| Pancreas | 3.35 | |
| PancreaticIslet | 5.15 | |
| ParietalLobe | 4.35 | |
| Pituitary | 4.95 | |
| Placenta | 4.1 | |
| Pons | 4 | |
| PrefrontalCortex | 5.4 | |
| Prostate | 4.95 | |
| Salivarygland | 3.65 | |
| SkeletalMuscle | 4.6 | |
| Skin | 3.15 | |
| SmoothMuscle | 4.7 | |
| Spinalcord | 4.7 | |
| SubthalamicNucleus | 3.75 | |
| SuperiorCervicalGanglion | 4.75 | |
| TemporalLobe | 3.8 | |
| Testis | 3.55 | |
| TestisGermCell | 3.6 | |
| TestisIntersitial | 3.45 | |
| TestisLeydigCell | 4.05 | |
| TestisSeminiferousTubule | 3.45 | |
| Thalamus | 4.25 | |
| Thymus | 3.45 | |
| Thyroid | 8.75 | |
| Tongue | 4.05 | |
| Tonsil | 12.35 | |
| Trachea | 3.35 | |
| TrigeminalGanglion | 4.45 | |
| Uterus | 4.05 | |
| UterusCorpus | 3.7 | |
| WholeBlood | 12.7 | |
| Wholebrain | 3.45 | |
| colon | 4.2 | |
| pineal_day | 8.22 | |
| pineal_night | 7.94 | |
| retina | 5.1 | |
| small_intestine | 3.95 | |
- Probe name: A_23_P434347
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.31 ± 0.19 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.36 ± 0.25 | |
| Basal Part of Pons | 6.38 ± 0.32 | |
| Cerebellar Cortex | 6.45 ± 0.28 | |
| Cerebellar Nuclei | 6.28 ± 0.28 | |
| Claustrum | 6.28 ± 0.42 | |
| Epithalamus | 6.33 ± 0.25 | |
| Frontal Lobe | 6.36 ± 0.34 | |
| Globus Pallidus | 6.39 ± 0.34 | |
| Hypothalamus | 6.28 ± 0.18 | |
| Insula | 6.29 ± 0.36 | |
| Limbic Lobe | 6.35 ± 0.32 | |
| Mesencephalon | 6.49 ± 0.32 | |
| Myelencephalon | 6.41 ± 0.33 | |
| Occipital Lobe | 6.76 ± 0.31 | |
| Parietal Lobe | 6.48 ± 0.24 | |
| Pontine Tegmentum | 6.46 ± 0.36 | |
| Striatum | 6.35 ± 0.36 | |
| Subthalamus | 6.33 ± 0.29 | |
| Temporal Lobe | 6.42 ± 0.3 | |
| Thalamus | 6.77 ± 0.33 | |
| White Matter | 7.14 ± 0.43 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Itsn2 | CB | Cerebellum | 9.44 | |
| 9.91 | | |||
| Itsn2 | CTX | Cerebral cortex | 24.71 | |
| 17.22 | | |||
| Itsn2 | HIP | Hippocampal region | 13.42 | |
| 11.91 | | |||
| Itsn2 | HPF | Hippocampal formation | 15.34 | |
| 12.61 | | |||
| Itsn2 | HY | Hypothalamus | 1.81 | |
| 1.28 | | |||
| Itsn2 | LSX | Lateral septal complex | 5.16 | |
| 3.64 | | |||
| Itsn2 | MB | Midbrain | 4.92 | |
| 4.51 | | |||
| Itsn2 | MY | Medulla | 12.52 | |
| 14.08 | | |||
| Itsn2 | OLF | Olfactory bulb | 24.38 | |
| 18.47 | | |||
| Itsn2 | P | Pons | 7.19 | |
| 7.91 | | |||
| Itsn2 | PAL | Pallidum | 4.24 | |
| 3.5 | | |||
| Itsn2 | RHP | Retrohippocampal region | 17.75 | |
| 12.98 | | |||
| Itsn2 | sAMY | Striatum-like amygdalar nuclei | 4.56 | |
| 3.04 | | |||
| Itsn2 | STR | Striatum | 4.67 | |
| 3.22 | | |||
| Itsn2 | STRd | Striatum dorsal region | 4.19 | |
| 2.96 | | |||
| Itsn2 | STRv | Striatum ventral region | 4.86 | |
| 3.01 | | |||
| Itsn2 | TH | Thalamus | 4.89 | |
| 3.66 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| ITSN2_HUMAN_104 | 12 | 104 | 115 | QPPMFSPLISAR | PRIDE |
| PAp00063362 | 19 | 314 | 332 | AGQPLPLTLPPELVPPSFR | Peptide Atlas |