AutismKB 2.0

Annotation Detail for NSDHL


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Basic Information Top
Gene Symbol:NSDHL ( H105E3,SDR31E1,XAP104 )
Gene Full Name: NAD(P) dependent steroid dehydrogenase-like
Band: Xq28
Quick LinksEntrez ID:50814; OMIM: 300275; Uniprot ID:NSDHL_HUMAN; ENSEMBL ID: ENSG00000147383; HGNC ID: 13398
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult70 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor13 / 119369108
germ cell tumor8 / 26384530
glioma4 / 10688337
head and neck tumor4 / 13630229
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor6 / 9635962
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal110 / 336030732
ovarian tumor8 / 76682104
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor9 / 12494972
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland8 / 33197240
ascites5 / 40015124
bladder2 / 2975767
blood6 / 12347848
bone2 / 7165527
bone marrow3 / 4880161
brain46 / 110098941
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus1 / 2020949
eye5 / 21105423
heart4 / 8962644
intestine12 / 23447251
kidney7 / 21177733
larynx1 / 2414541
liver12 / 20774357
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle3 / 10771527
nerve1 / 1576863
ovary9 / 10205188
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta5 / 28082517
prostate7 / 18934536
salivary gland2 / 2015599
skin13 / 21057461
spleen1 / 5395218
stomach5 / 9661951
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215093_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.35
Adipocyte42
AdrenalCortex52.9
Adrenalgland6.8
Amygdala6.65
Appendix7.75
AtrioventricularNode8.15
BDCA4+_DentriticCells8.25
Bonemarrow7.35
BronchialEpithelialCells35.15
CD105+_Endothelial14.65
CD14+_Monocytes7.5
CD19+_BCells(neg._sel.)7
CD33+_Myeloid8.6
CD34+9.6
CD4+_Tcells7.3
CD56+_NKCells8.05
CD71+_EarlyErythroid7.5
CD8+_Tcells6.45
CardiacMyocytes10.3
Caudatenucleus6.4
Cerebellum5.75
CerebellumPeduncles8.4
CiliaryGanglion9.4
CingulateCortex7.3
Colorectaladenocarcinoma10.65
DorsalRootGanglion6.75
FetalThyroid7.1
Fetalbrain7.45
Fetalliver6.5
Fetallung5.3
GlobusPallidus5.8
Heart10.2
Hypothalamus8.35
Kidney6.6
Leukemia_chronicMyelogenousK-56210.65
Leukemia_promyelocytic-HL-607.25
Leukemialymphoblastic(MOLT-4)5.8
Liver10.85
Lung8.05
Lymphnode5.4
Lymphoma_burkitts(Daudi)11.05
Lymphoma_burkitts(Raji)10.45
MedullaOblongata6.25
OccipitalLobe6.2
OlfactoryBulb5.65
Ovary5.15
Pancreas6
PancreaticIslet7.8
ParietalLobe9.3
Pituitary8.1
Placenta7
Pons6.9
PrefrontalCortex8.7
Prostate8
Salivarygland7
SkeletalMuscle9.65
Skin7.9
SmoothMuscle8.75
Spinalcord7.85
SubthalamicNucleus6.95
SuperiorCervicalGanglion9.15
TemporalLobe6.6
Testis6.05
TestisGermCell5.55
TestisIntersitial5.95
TestisLeydigCell7.2
TestisSeminiferousTubule6
Thalamus7.45
Thymus5.25
Thyroid8.25
Tongue8.8
Tonsil7.3
Trachea5.85
TrigeminalGanglion8.35
Uterus5.45
UterusCorpus7.25
WholeBlood7.35
Wholebrain6.45
colon7.35
pineal_day8.2
pineal_night8.66
retina9.1
small_intestine9.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P171034
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.64 ± 0.91
Basal Forebrain3.02 ± 0.41
Basal Part of Pons3.45 ± 0.73
Cerebellar Cortex3.27 ± 0.62
Cerebellar Nuclei3.42 ± 0.55
Claustrum3.63 ± 0.59
Epithalamus3.03 ± 0.76
Frontal Lobe3.66 ± 0.57
Globus Pallidus3.29 ± 0.86
Hypothalamus3.09 ± 0.66
Insula3.72 ± 0.39
Limbic Lobe3.3 ± 0.61
Mesencephalon3.4 ± 0.62
Myelencephalon3.35 ± 0.58
Occipital Lobe2.89 ± 0.61
Parietal Lobe3.23 ± 0.56
Pontine Tegmentum3.51 ± 0.71
Striatum2.94 ± 0.67
Subthalamus3.3 ± 0.64
Temporal Lobe3.48 ± 0.58
Thalamus3.45 ± 0.57
White Matter2.76 ± 0.86
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
NsdhlCBCerebellum0
0
NsdhlCTXCerebral cortex0
0
NsdhlHIPHippocampal region0
0
NsdhlHPFHippocampal formation0
0
NsdhlHYHypothalamus0
0
NsdhlLSXLateral septal complex0
0
NsdhlMBMidbrain0
0
NsdhlMYMedulla0
0
NsdhlOLFOlfactory bulb0
0
NsdhlPPons0
0
NsdhlPALPallidum0
0
NsdhlRHPRetrohippocampal region0
0
NsdhlsAMYStriatum-like amygdalar nuclei0
0
NsdhlSTRStriatum0
0
NsdhlSTRdStriatum dorsal region0
0
NsdhlSTRvStriatum ventral region0
0
NsdhlTHThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NSDHL_HUMAN_1 10 1 10 MEPAVSEPMR PRIDE
PAp00001429 21 40 60 CTVIGGSGFLGQHMVEQLLAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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