AutismKB 2.0

Annotation Detail for PDCL


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PDCL ( DKFZp564M1863,PhLP )
Gene Full Name: phosducin-like
Band: 9q33.2
Quick LinksEntrez ID:5082; OMIM: 604421; Uniprot ID:PHLP_HUMAN; ENSEMBL ID: ENSG00000136940; HGNC ID: 8770
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult46 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor2 / 17290115
gastrointestinal tumor0 / 1193690 
germ cell tumor12 / 26384545
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal95 / 336030728
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone8 / 71655111
bone marrow1 / 4880120
brain30 / 110098927
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus2 / 2020998
eye7 / 21105433
heart0 / 896260 
intestine2 / 2344728
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph1 / 4427022
lymph node1 / 9161010
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary2 / 10205119
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta14 / 28082549
prostate5 / 18934526
salivary gland1 / 2015549
skin4 / 21057418
spleen4 / 5395274
stomach0 / 966190 
testis5 / 33044215
thymus2 / 8113124
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204448_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.5
Adipocyte3.45
AdrenalCortex3.6
Adrenalgland2.9
Amygdala3.65
Appendix3.45
AtrioventricularNode2.6
BDCA4+_DentriticCells4.05
Bonemarrow3.4
BronchialEpithelialCells3.45
CD105+_Endothelial7.85
CD14+_Monocytes3.75
CD19+_BCells(neg._sel.)4.55
CD33+_Myeloid4.6
CD34+7.65
CD4+_Tcells3.9
CD56+_NKCells7.6
CD71+_EarlyErythroid4.55
CD8+_Tcells3.45
CardiacMyocytes4.4
Caudatenucleus3.15
Cerebellum2.8
CerebellumPeduncles3.95
CiliaryGanglion2.45
CingulateCortex3.55
Colorectaladenocarcinoma3.5
DorsalRootGanglion2.65
FetalThyroid3.4
Fetalbrain3.5
Fetalliver3
Fetallung2.95
GlobusPallidus2.55
Heart4.4
Hypothalamus3.8
Kidney2.8
Leukemia_chronicMyelogenousK-5623.15
Leukemia_promyelocytic-HL-603.1
Leukemialymphoblastic(MOLT-4)2.8
Liver4.55
Lung3.8
Lymphnode3.05
Lymphoma_burkitts(Daudi)4.45
Lymphoma_burkitts(Raji)4.8
MedullaOblongata3.25
OccipitalLobe3.15
OlfactoryBulb2.75
Ovary2.3
Pancreas2.8
PancreaticIslet3.7
ParietalLobe3.65
Pituitary4.1
Placenta3.7
Pons3.3
PrefrontalCortex4.35
Prostate4.1
Salivarygland2.8
SkeletalMuscle3.95
Skin2.75
SmoothMuscle4
Spinalcord3.75
SubthalamicNucleus3.15
SuperiorCervicalGanglion3.9
TemporalLobe3.2
Testis3
TestisGermCell2.9
TestisIntersitial2.95
TestisLeydigCell3.45
TestisSeminiferousTubule3
Thalamus3.55
Thymus2.8
Thyroid4.4
Tongue3.35
Tonsil3.4
Trachea2.9
TrigeminalGanglion3.45
Uterus2.9
UterusCorpus3.05
WholeBlood3.85
Wholebrain2.95
colon3.5
pineal_day4.42
pineal_night4.3
retina4.275
small_intestine3.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P216949
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.35 ± 0.27
Basal Forebrain6.74 ± 0.3
Basal Part of Pons6.75 ± 0.26
Cerebellar Cortex6.59 ± 0.21
Cerebellar Nuclei7.09 ± 0.12
Claustrum6.41 ± 0.48
Epithalamus6.72 ± 0.29
Frontal Lobe6.56 ± 0.3
Globus Pallidus7.38 ± 0.28
Hypothalamus6.73 ± 0.25
Insula6.43 ± 0.23
Limbic Lobe6.51 ± 0.28
Mesencephalon6.69 ± 0.29
Myelencephalon6.6 ± 0.26
Occipital Lobe6.67 ± 0.29
Parietal Lobe6.62 ± 0.29
Pontine Tegmentum6.57 ± 0.29
Striatum6.54 ± 0.34
Subthalamus6.89 ± 0.2
Temporal Lobe6.43 ± 0.26
Thalamus6.63 ± 0.2
White Matter7.39 ± 0.09
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PdclCBCerebellum18.48
40.77
PdclCTXCerebral cortex11.94
8.19
PdclHIPHippocampal region8.56
8.86
PdclHPFHippocampal formation9.73
9.34
PdclHYHypothalamus2.04
2.05
PdclLSXLateral septal complex1.43
1.04
PdclMBMidbrain2.78
2.92
PdclMYMedulla9.5
10.35
PdclOLFOlfactory bulb9.36
7.05
PdclPPons6.1
7.58
PdclPALPallidum5.41
5.38
PdclRHPRetrohippocampal region11.07
9.34
PdclsAMYStriatum-like amygdalar nuclei3
2.57
PdclSTRStriatum2.66
2.03
PdclSTRdStriatum dorsal region2.7
2.1
PdclSTRvStriatum ventral region2.44
1.52
PdclTHThalamus5.64
4.66
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00077471 11 97 107 SHLDEEEEQQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved