AutismKB 2.0

Annotation Detail for CLEC4A


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Basic Information Top
Gene Symbol:CLEC4A ( CLECSF6,DCIR,DDB27,LLIR )
Gene Full Name: C-type lectin domain family 4, member A
Band: 12p13.31
Quick LinksEntrez ID:50856; OMIM: 605306; Uniprot ID:CLC4A_HUMAN; ENSEMBL ID: ENSG00000111729; HGNC ID: 13257
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult7 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal20 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain0 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219947_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.35
Adipocyte7.05
AdrenalCortex8.5
Adrenalgland6.55
Amygdala7
Appendix9.4
AtrioventricularNode7.7
BDCA4+_DentriticCells227.95
Bonemarrow9.9
BronchialEpithelialCells6.9
CD105+_Endothelial7.95
CD14+_Monocytes552.95
CD19+_BCells(neg._sel.)29.4
CD33+_Myeloid862.1
CD34+12.75
CD4+_Tcells9.2
CD56+_NKCells8.75
CD71+_EarlyErythroid6.9
CD8+_Tcells6.9
CardiacMyocytes11.7
Caudatenucleus6.5
Cerebellum5.8
CerebellumPeduncles8.5
CiliaryGanglion6.55
CingulateCortex7.55
Colorectaladenocarcinoma7.2
DorsalRootGanglion6.5
FetalThyroid7.45
Fetalbrain7
Fetalliver6.3
Fetallung5.8
GlobusPallidus6.05
Heart13.05
Hypothalamus7.6
Kidney6.8
Leukemia_chronicMyelogenousK-5626.4
Leukemia_promyelocytic-HL-606.4
Leukemialymphoblastic(MOLT-4)5.4
Liver11.25
Lung7.9
Lymphnode6.2
Lymphoma_burkitts(Daudi)9.5
Lymphoma_burkitts(Raji)12.6
MedullaOblongata6.45
OccipitalLobe6.5
OlfactoryBulb5.7
Ovary5.9
Pancreas6.2
PancreaticIslet7.75
ParietalLobe8.25
Pituitary8.35
Placenta7.4
Pons7.1
PrefrontalCortex8.45
Prostate8.3
Salivarygland6.4
SkeletalMuscle11.3
Skin7.3
SmoothMuscle8.15
Spinalcord7.55
SubthalamicNucleus7.15
SuperiorCervicalGanglion13.3
TemporalLobe7.05
Testis6.1
TestisGermCell5.55
TestisIntersitial6.55
TestisLeydigCell7.4
TestisSeminiferousTubule6.1
Thalamus7.65
Thymus5.5
Thyroid8.8
Tongue8.75
Tonsil7.1
Trachea6
TrigeminalGanglion10.5
Uterus5.8
UterusCorpus8.05
WholeBlood550.7
Wholebrain5.75
colon7.25
pineal_day9.24
pineal_night9.44
retina8.825
small_intestine7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14229_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.42 ± 0.9
Basal Forebrain2.95 ± 0.59
Basal Part of Pons3.21 ± 0.52
Cerebellar Cortex3.48 ± 0.58
Cerebellar Nuclei3.48 ± 0.55
Claustrum3.8 ± 0.9
Epithalamus3.23 ± 0.58
Frontal Lobe3.25 ± 0.61
Globus Pallidus3.62 ± 0.56
Hypothalamus3.37 ± 0.71
Insula3.18 ± 0.57
Limbic Lobe3.26 ± 0.69
Mesencephalon3.37 ± 0.72
Myelencephalon3.33 ± 0.63
Occipital Lobe3.11 ± 0.76
Parietal Lobe3.27 ± 0.71
Pontine Tegmentum3.21 ± 0.68
Striatum3.15 ± 0.7
Subthalamus3.04 ± 0.49
Temporal Lobe3.25 ± 0.58
Thalamus3.29 ± 0.55
White Matter3.72 ± 0.43
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CLC4A_HUMAN_27 6 27 32 AASKER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018