Annotation Detail for PBX3
Basic Information Top
| Gene Symbol: | PBX3 ( - ) |
|---|---|
| Gene Full Name: | pre-B-cell leukemia homeobox 3 |
| Band: | 9q33.3 |
| Quick Links | Entrez ID:5090; OMIM: 176312; Uniprot ID:PBX3_HUMAN; ENSEMBL ID: ENSG00000167081; HGNC ID: 8634 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.428027
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 4 / 70761 | 56 |  |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 33 / 564012 | 58 | |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 83 / 1939121 | 42 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 33 / 263845 | 125 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 115 / 3360307 | 34 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 1 / 102680 | 9 |  |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 8 / 125191 | 63 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 4 / 33197 | 120 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 2 / 29757 | 67 | |
| blood | 1 / 123478 | 8 | |
| bone | 5 / 71655 | 69 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 31 / 1100989 | 28 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 11 / 149255 | 73 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 6 / 215722 | 27 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 8 / 211054 | 37 | |
| heart | 3 / 89626 | 33 | |
| intestine | 5 / 234472 | 21 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 2 / 24145 | 82 | |
| liver | 5 / 207743 | 24 | |
| lung | 11 / 336974 | 32 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 12 / 214812 | 55 | |
| parathyroid | 3 / 20539 | 146 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 2 / 96619 | 20 | |
| testis | 18 / 330442 | 54 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204082_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 118.8 | |
| Adipocyte | 4.2 | |
| AdrenalCortex | 35.25 | |
| Adrenalgland | 31.7 | |
| Amygdala | 4.35 | |
| Appendix | 4.25 | |
| AtrioventricularNode | 2.95 | |
| BDCA4+_DentriticCells | 54.7 | |
| Bonemarrow | 4.1 | |
| BronchialEpithelialCells | 4.2 | |
| CD105+_Endothelial | 5.35 | |
| CD14+_Monocytes | 16.35 | |
| CD19+_BCells(neg._sel.) | 32.45 | |
| CD33+_Myeloid | 24.5 | |
| CD34+ | 24.1 | |
| CD4+_Tcells | 16.6 | |
| CD56+_NKCells | 15.15 | |
| CD71+_EarlyErythroid | 6.4 | |
| CD8+_Tcells | 11.55 | |
| CardiacMyocytes | 7.45 | |
| Caudatenucleus | 4.35 | |
| Cerebellum | 3.35 | |
| CerebellumPeduncles | 4.75 | |
| CiliaryGanglion | 3 | |
| CingulateCortex | 4.3 | |
| Colorectaladenocarcinoma | 4.25 | |
| DorsalRootGanglion | 3.15 | |
| FetalThyroid | 9.55 | |
| Fetalbrain | 3.5 | |
| Fetalliver | 3.6 | |
| Fetallung | 5.45 | |
| GlobusPallidus | 3.05 | |
| Heart | 5.2 | |
| Hypothalamus | 8.45 | |
| Kidney | 3.3 | |
| Leukemia_chronicMyelogenousK-562 | 3.75 | |
| Leukemia_promyelocytic-HL-60 | 3.7 | |
| Leukemialymphoblastic(MOLT-4) | 3.45 | |
| Liver | 5.45 | |
| Lung | 4.6 | |
| Lymphnode | 3.7 | |
| Lymphoma_burkitts(Daudi) | 5.35 | |
| Lymphoma_burkitts(Raji) | 5.75 | |
| MedullaOblongata | 4.05 | |
| OccipitalLobe | 3.45 | |
| OlfactoryBulb | 4.5 | |
| Ovary | 44.6 | |
| Pancreas | 3.35 | |
| PancreaticIslet | 4.8 | |
| ParietalLobe | 4.35 | |
| Pituitary | 6.1 | |
| Placenta | 3.9 | |
| Pons | 4 | |
| PrefrontalCortex | 4.65 | |
| Prostate | 14.4 | |
| Salivarygland | 3.4 | |
| SkeletalMuscle | 4.65 | |
| Skin | 3.1 | |
| SmoothMuscle | 4.8 | |
| Spinalcord | 11.15 | |
| SubthalamicNucleus | 3.8 | |
| SuperiorCervicalGanglion | 4.6 | |
| TemporalLobe | 3.75 | |
| Testis | 3.6 | |
| TestisGermCell | 5 | |
| TestisIntersitial | 3.45 | |
| TestisLeydigCell | 4.1 | |
| TestisSeminiferousTubule | 3.6 | |
| Thalamus | 4.5 | |
| Thymus | 3.4 | |
| Thyroid | 15.05 | |
| Tongue | 4.1 | |
| Tonsil | 4.1 | |
| Trachea | 3.5 | |
| TrigeminalGanglion | 5.25 | |
| Uterus | 3.55 | |
| UterusCorpus | 3.75 | |
| WholeBlood | 4.55 | |
| Wholebrain | 3.55 | |
| colon | 4.3 | |
| pineal_day | 67.18 | |
| pineal_night | 48.5 | |
| retina | 12.2 | |
| small_intestine | 4.15 | |
- Probe name: A_23_P71821
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.57 ± 0.56 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.69 ± 0.36 | |
| Basal Part of Pons | 5.49 ± 0.42 | |
| Cerebellar Cortex | 5.69 ± 0.26 | |
| Cerebellar Nuclei | 7.15 ± 0.36 | |
| Claustrum | 5.43 ± 0.59 | |
| Epithalamus | 5.94 ± 0.57 | |
| Frontal Lobe | 5.9 ± 0.6 | |
| Globus Pallidus | 7.28 ± 0.72 | |
| Hypothalamus | 6.53 ± 0.24 | |
| Insula | 5.97 ± 0.41 | |
| Limbic Lobe | 5.22 ± 0.6 | |
| Mesencephalon | 6.36 ± 0.62 | |
| Myelencephalon | 6.07 ± 0.56 | |
| Occipital Lobe | 5.62 ± 0.67 | |
| Parietal Lobe | 6.02 ± 0.54 | |
| Pontine Tegmentum | 6.36 ± 0.61 | |
| Striatum | 7.77 ± 0.77 | |
| Subthalamus | 7.37 ± 0.33 | |
| Temporal Lobe | 5.61 ± 0.41 | |
| Thalamus | 6.31 ± 0.47 | |
| White Matter | 7.27 ± 0.37 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Pbx3 | CB | Cerebellum | 11.84 | |
| 12.28 | | |||
| Pbx3 | CTX | Cerebral cortex | 7.92 | |
| 4.1 | | |||
| Pbx3 | HIP | Hippocampal region | 3.29 | |
| 2.75 | | |||
| Pbx3 | HPF | Hippocampal formation | 8.28 | |
| 4.6 | | |||
| Pbx3 | HY | Hypothalamus | 31.29 | |
| 22.84 | | |||
| Pbx3 | LSX | Lateral septal complex | 35.61 | |
| 19.97 | | |||
| Pbx3 | MB | Midbrain | 38.81 | |
| 29.39 | | |||
| Pbx3 | MY | Medulla | 27.91 | |
| 21.93 | | |||
| Pbx3 | OLF | Olfactory bulb | 59.81 | |
| 78.44 | | |||
| Pbx3 | P | Pons | 46.01 | |
| 31.27 | | |||
| Pbx3 | PAL | Pallidum | 36.62 | |
| 29.01 | | |||
| Pbx3 | RHP | Retrohippocampal region | 14.37 | |
| 6.33 | | |||
| Pbx3 | sAMY | Striatum-like amygdalar nuclei | 82.8 | |
| 51.99 | | |||
| Pbx3 | STR | Striatum | 67.94 | |
| 36.95 | | |||
| Pbx3 | STRd | Striatum dorsal region | 61.97 | |
| 31.73 | | |||
| Pbx3 | STRv | Striatum ventral region | 87.18 | |
| 46.88 | | |||
| Pbx3 | TH | Thalamus | 9.26 | |
| 6.68 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00010336 | 7 | 69 | 75 | HALNCHR | Peptide Atlas |