AutismKB 2.0

Annotation Detail for AMDHD2


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Basic Information Top
Gene Symbol:AMDHD2 ( - )
Gene Full Name: amidohydrolase domain containing 2
Band: 16p13.3
Quick LinksEntrez ID:51005; OMIM: NA; Uniprot ID:NAGA_HUMAN; ENSEMBL ID: ENSG00000162066; HGNC ID: 24262
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219082_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.45
Adipocyte4.1
AdrenalCortex4.3
Adrenalgland3.5
Amygdala4.35
Appendix4.2
AtrioventricularNode3.25
BDCA4+_DentriticCells14.95
Bonemarrow4.3
BronchialEpithelialCells4.15
CD105+_Endothelial4.2
CD14+_Monocytes4.65
CD19+_BCells(neg._sel.)6.05
CD33+_Myeloid5.35
CD34+5.3
CD4+_Tcells5.4
CD56+_NKCells6
CD71+_EarlyErythroid3.9
CD8+_Tcells5.2
CardiacMyocytes6.2
Caudatenucleus3.75
Cerebellum3.3
CerebellumPeduncles4.7
CiliaryGanglion2.9
CingulateCortex4.25
Colorectaladenocarcinoma4.2
DorsalRootGanglion3.15
FetalThyroid4.05
Fetalbrain4.1
Fetalliver3.65
Fetallung3.4
GlobusPallidus3.05
Heart5.95
Hypothalamus4.45
Kidney3.35
Leukemia_chronicMyelogenousK-5623.75
Leukemia_promyelocytic-HL-603.7
Leukemialymphoblastic(MOLT-4)3.35
Liver5.7
Lung4.65
Lymphnode3.6
Lymphoma_burkitts(Daudi)5.3
Lymphoma_burkitts(Raji)5.95
MedullaOblongata3.8
OccipitalLobe3.75
OlfactoryBulb3.3
Ovary2.75
Pancreas3.3
PancreaticIslet4.45
ParietalLobe4.35
Pituitary4.85
Placenta4.35
Pons3.9
PrefrontalCortex5.2
Prostate4.85
Salivarygland3.3
SkeletalMuscle4.9
Skin3.2
SmoothMuscle4.7
Spinalcord4.4
SubthalamicNucleus3.8
SuperiorCervicalGanglion4.75
TemporalLobe3.75
Testis5.75
TestisGermCell3.55
TestisIntersitial3.55
TestisLeydigCell4.15
TestisSeminiferousTubule3.6
Thalamus4.25
Thymus3.3
Thyroid5.2
Tongue4.2
Tonsil4.05
Trachea3.5
TrigeminalGanglion4.25
Uterus3.4
UterusCorpus3.7
WholeBlood4.6
Wholebrain3.5
colon4.2
pineal_day5.22
pineal_night5.08
retina5.075
small_intestine4.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P49351
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.69 ± 1.17
Basal Forebrain2.23 ± 0.31
Basal Part of Pons1.97 ± 0.65
Cerebellar Cortex2.51 ± 0.87
Cerebellar Nuclei2.5 ± 0.74
Claustrum3.1 ± 0.8
Epithalamus2.25 ± 0.65
Frontal Lobe2.39 ± 0.84
Globus Pallidus2.29 ± 0.59
Hypothalamus2.22 ± 0.74
Insula2.66 ± 0.77
Limbic Lobe2.19 ± 0.77
Mesencephalon2.39 ± 0.71
Myelencephalon2.31 ± 0.76
Occipital Lobe1.86 ± 0.72
Parietal Lobe2.08 ± 0.67
Pontine Tegmentum2.34 ± 0.81
Striatum1.87 ± 0.52
Subthalamus2.53 ± 0.82
Temporal Lobe2.32 ± 0.8
Thalamus2.17 ± 0.65
White Matter2.24 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Amdhd2CBCerebellum0.89
1.21
Amdhd2CTXCerebral cortex1.19
0.9
Amdhd2HIPHippocampal region4.17
3.57
Amdhd2HPFHippocampal formation4.02
3.2
Amdhd2HYHypothalamus1.24
1.32
Amdhd2LSXLateral septal complex0.26
0.29
Amdhd2MBMidbrain0.79
1.26
Amdhd2MYMedulla4.26
4.02
Amdhd2OLFOlfactory bulb8.2
5.96
Amdhd2PPons3.15
3.58
Amdhd2PALPallidum1.83
1.42
Amdhd2RHPRetrohippocampal region3.59
2.58
Amdhd2sAMYStriatum-like amygdalar nuclei5.84
3.67
Amdhd2STRStriatum1.25
0.85
Amdhd2STRdStriatum dorsal region0.68
0.48
Amdhd2STRvStriatum ventral region2.03
1.33
Amdhd2THThalamus0.35
0.32
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00025671 29 371 399 HFLQATGCSMESALEAASLHPAQLLGLEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018