AutismKB 2.0

Annotation Detail for PAM16


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PAM16 ( Magmas,TIMM16,Tim16 )
Gene Full Name: presequence translocase-associated motor 16 homolog (S. cerevisiae)
Band: 16p13.3
Quick LinksEntrez ID:51025; OMIM: NA; Uniprot ID:TIM16_HUMAN; ENSEMBL ID: ENSG00000217930; HGNC ID: 29679
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218969_at
Cell line Expression level Expression bar
721_B_lymphoblasts67.65
Adipocyte54
AdrenalCortex68.2
Adrenalgland45.25
Amygdala59.3
Appendix55.9
AtrioventricularNode38.35
BDCA4+_DentriticCells58.95
Bonemarrow52.7
BronchialEpithelialCells69.4
CD105+_Endothelial71.65
CD14+_Monocytes58
CD19+_BCells(neg._sel.)56.4
CD33+_Myeloid72.4
CD34+70.75
CD4+_Tcells56.4
CD56+_NKCells63.15
CD71+_EarlyErythroid44.5
CD8+_Tcells58.15
CardiacMyocytes61.25
Caudatenucleus54.35
Cerebellum43.4
CerebellumPeduncles63.1
CiliaryGanglion39.5
CingulateCortex56.6
Colorectaladenocarcinoma44.7
DorsalRootGanglion42.3
FetalThyroid60.65
Fetalbrain53.5
Fetalliver40.55
Fetallung42.6
GlobusPallidus48.75
Heart213.85
Hypothalamus57.05
Kidney44
Leukemia_chronicMyelogenousK-56281.8
Leukemia_promyelocytic-HL-6093.65
Leukemialymphoblastic(MOLT-4)47.3
Liver122.85
Lung67.25
Lymphnode45.65
Lymphoma_burkitts(Daudi)110
Lymphoma_burkitts(Raji)201.35
MedullaOblongata49.1
OccipitalLobe47.85
OlfactoryBulb45.7
Ovary30.6
Pancreas38.45
PancreaticIslet58.4
ParietalLobe56.3
Pituitary63.5
Placenta52.15
Pons58.6
PrefrontalCortex73.55
Prostate62.8
Salivarygland42.8
SkeletalMuscle97.2
Skin42.6
SmoothMuscle51.35
Spinalcord57.8
SubthalamicNucleus58.2
SuperiorCervicalGanglion60.05
TemporalLobe65.85
Testis47.65
TestisGermCell48.25
TestisIntersitial53.05
TestisLeydigCell54.8
TestisSeminiferousTubule66.4
Thalamus63.75
Thymus36.65
Thyroid62
Tongue58
Tonsil52.05
Trachea41.3
TrigeminalGanglion52.4
Uterus38.5
UterusCorpus50.35
WholeBlood43.7
Wholebrain62.35
colon24.9
pineal_day102.62
pineal_night88.62
retina55.225
small_intestine29.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1834_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.99 ± 0.26
Basal Forebrain6.94 ± 0.13
Basal Part of Pons7.24 ± 0.22
Cerebellar Cortex6.87 ± 0.18
Cerebellar Nuclei7.03 ± 0.21
Claustrum6.72 ± 0.35
Epithalamus6.65 ± 0.23
Frontal Lobe7.11 ± 0.3
Globus Pallidus6.83 ± 0.25
Hypothalamus7.17 ± 0.33
Insula7.07 ± 0.36
Limbic Lobe7.07 ± 0.31
Mesencephalon6.98 ± 0.29
Myelencephalon6.97 ± 0.33
Occipital Lobe6.86 ± 0.2
Parietal Lobe7.04 ± 0.28
Pontine Tegmentum7.04 ± 0.31
Striatum7.26 ± 0.29
Subthalamus7.19 ± 0.08
Temporal Lobe7.14 ± 0.26
Thalamus6.88 ± 0.29
White Matter6.5 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MagmasCBCerebellum19.17
29.69
MagmasCTXCerebral cortex37.59
31.81
MagmasHIPHippocampal region29.35
28.79
MagmasHPFHippocampal formation31.06
32.22
MagmasHYHypothalamus22.37
16.92
MagmasLSXLateral septal complex10.06
6.99
MagmasMBMidbrain15.28
13.37
MagmasMYMedulla21.47
23.74
MagmasOLFOlfactory bulb50
43.3
MagmasPPons25.8
26.09
MagmasPALPallidum13.11
11.31
MagmasRHPRetrohippocampal region33.77
35.13
MagmassAMYStriatum-like amygdalar nuclei24.75
16.38
MagmasSTRStriatum11.19
7.74
MagmasSTRdStriatum dorsal region6.06
4.21
MagmasSTRvStriatum ventral region21.58
14.09
MagmasTHThalamus31.06
25.11
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00043332 15 4 18 YLAQIIVMGVQVVGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018