AutismKB 2.0

Annotation Detail for GLOD4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GLOD4 ( C17orf25,HC71 )
Gene Full Name: glyoxalase domain containing 4
Band: 17p13.3
Quick LinksEntrez ID:51031; OMIM: NA; Uniprot ID:GLOD4_HUMAN; ENSEMBL ID: ENSG00000167699; HGNC ID: 14111
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst1 / 6231916
fetus48 / 56401285
neonate4 / 31097128
infant5 / 23620211
juvenile3 / 5555653
adult158 / 193912181
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma6 / 17475343
breast (mammary gland) tumor2 / 9417821
cervical tumor5 / 34366145
chondrosarcoma6 / 8282372
colorectal tumor8 / 11424670
esophageal tumor2 / 17290115
gastrointestinal tumor17 / 119369142
germ cell tumor18 / 26384568
glioma7 / 10688365
head and neck tumor14 / 136302102
kidney tumor4 / 6895958
leukemia7 / 9584273
liver tumor7 / 9635972
lung tumor3 / 10312729
lymphoma7 / 7175597
non-neoplasia6 / 9725061
normal281 / 336030783
ovarian tumor6 / 7668278
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer2 / 10268019
retinoblastoma3 / 4635664
skin tumor4 / 12494932
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland4 / 33197120
ascites9 / 40015224
bladder8 / 29757268
blood10 / 12347880
bone6 / 7165583
bone marrow1 / 4880120
brain70 / 110098963
cervix12 / 48171249
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus4 / 20209197
eye13 / 21105461
heart4 / 8962644
intestine23 / 23447298
kidney15 / 21177770
larynx0 / 241450 
liver16 / 20774377
lung16 / 33697447
lymph7 / 44270158
lymph node2 / 9161021
mammary gland6 / 15327139
mouth8 / 67052119
muscle3 / 10771527
nerve0 / 157680 
ovary9 / 10205188
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx12 / 41328290
pituitary gland2 / 16585120
placenta36 / 280825128
prostate4 / 18934521
salivary gland2 / 2015599
skin7 / 21057433
spleen1 / 5395218
stomach12 / 96619124
testis29 / 33044287
thymus2 / 8113124
thyroid3 / 4747363
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord3 / 13680219
uterus23 / 23287898
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209092_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts287
Adipocyte43.4
AdrenalCortex31
Adrenalgland52.15
Amygdala108.25
Appendix40.15
AtrioventricularNode11.9
BDCA4+_DentriticCells114.5
Bonemarrow61.05
BronchialEpithelialCells174.3
CD105+_Endothelial116.4
CD14+_Monocytes150
CD19+_BCells(neg._sel.)163.25
CD33+_Myeloid83.2
CD34+254.8
CD4+_Tcells218.9
CD56+_NKCells172.45
CD71+_EarlyErythroid35.75
CD8+_Tcells236.15
CardiacMyocytes44.85
Caudatenucleus53.5
Cerebellum39.8
CerebellumPeduncles46.7
CiliaryGanglion15.7
CingulateCortex58.75
Colorectaladenocarcinoma106.25
DorsalRootGanglion27.2
FetalThyroid34.15
Fetalbrain164.75
Fetalliver42.15
Fetallung71.3
GlobusPallidus33.45
Heart21.75
Hypothalamus184.8
Kidney84.15
Leukemia_chronicMyelogenousK-56246.9
Leukemia_promyelocytic-HL-60141.95
Leukemialymphoblastic(MOLT-4)83.1
Liver37.85
Lung50
Lymphnode49.35
Lymphoma_burkitts(Daudi)189.05
Lymphoma_burkitts(Raji)72.6
MedullaOblongata47.7
OccipitalLobe56.7
OlfactoryBulb57.4
Ovary23.55
Pancreas38.8
PancreaticIslet109.1
ParietalLobe43.5
Pituitary98.55
Placenta128.6
Pons26.1
PrefrontalCortex127.95
Prostate48.05
Salivarygland47.95
SkeletalMuscle33.9
Skin40.35
SmoothMuscle74.3
Spinalcord67.45
SubthalamicNucleus48.75
SuperiorCervicalGanglion25.2
TemporalLobe48.15
Testis22.1
TestisGermCell60.8
TestisIntersitial28.05
TestisLeydigCell27.1
TestisSeminiferousTubule32.5
Thalamus59.95
Thymus100.1
Thyroid102.35
Tongue39.15
Tonsil75.45
Trachea54
TrigeminalGanglion12.9
Uterus34.65
UterusCorpus29.55
WholeBlood79.25
Wholebrain103.15
colon145.6
pineal_day176.4
pineal_night236.8
retina155.25
small_intestine257.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8707_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.98 ± 0.43
Basal Forebrain7.53 ± 0.26
Basal Part of Pons7.5 ± 0.37
Cerebellar Cortex7.06 ± 0.3
Cerebellar Nuclei7.4 ± 0.22
Claustrum8.08 ± 0.46
Epithalamus7.08 ± 0.62
Frontal Lobe7.35 ± 0.42
Globus Pallidus7.55 ± 0.25
Hypothalamus7.72 ± 0.29
Insula7.54 ± 0.37
Limbic Lobe7.7 ± 0.38
Mesencephalon7.5 ± 0.34
Myelencephalon7.42 ± 0.39
Occipital Lobe7.29 ± 0.29
Parietal Lobe7.38 ± 0.48
Pontine Tegmentum7.43 ± 0.43
Striatum7.52 ± 0.46
Subthalamus7.02 ± 0.18
Temporal Lobe7.51 ± 0.35
Thalamus7.22 ± 0.32
White Matter7.54 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2700085E05RikCBCerebellum34.18
45.47
2700085E05RikCTXCerebral cortex100
91.77
2700085E05RikHIPHippocampal region60.25
82.82
2700085E05RikHPFHippocampal formation75.04
87
2700085E05RikHYHypothalamus58.83
49.08
2700085E05RikLSXLateral septal complex85.97
72.94
2700085E05RikMBMidbrain55.63
50.37
2700085E05RikMYMedulla47.5
48.81
2700085E05RikOLFOlfactory bulb90.81
84.31
2700085E05RikPPons49.23
47.42
2700085E05RikPALPallidum65.74
62.92
2700085E05RikRHPRetrohippocampal region100
100
2700085E05RiksAMYStriatum-like amygdalar nuclei81.36
68.77
2700085E05RikSTRStriatum69.56
55.52
2700085E05RikSTRdStriatum dorsal region64.95
52.12
2700085E05RikSTRvStriatum ventral region67.76
49.63
2700085E05RikTHThalamus69.89
63.4
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GLOD4_HUMAN_0 0 0 0 IAFSCPQKELPDLEDLMK PRIDE
GLOD4_HUMAN_0 0 0 0 ILTPLVSLDTPGK PRIDE
GLOD4_HUMAN_0 0 0 0 VTLAVSDLQK PRIDE
GLOD4_HUMAN_116 23 116 138 KLEWPLTEVAEGVFETEAPGGYK PRIDE
GLOD4_HUMAN_145 10 145 154 SLPQSDPVLK PRIDE
GLOD4_HUMAN_145 20 145 164 SLPQSDPVLKVTLAVSDLQK PRIDE
GLOD4_HUMAN_155 10 155 164 VTLAVSDLQK PRIDE
GLOD4_HUMAN_165 12 165 176 SLNYWCNLLGMK PRIDE
GLOD4_HUMAN_187 11 187 197 ALLGYADNQCK PRIDE
GLOD4_HUMAN_187 18 187 204 ALLGYADNQCKLELQGVK PRIDE
GLOD4_HUMAN_216 18 216 233 IAFSCPQKELPDLEDLMK PRIDE
GLOD4_HUMAN_216 19 216 234 IAFSCPQKELPDLEDLMKR PRIDE
GLOD4_HUMAN_239 13 239 251 ILTPLVSLDTPGK PRIDE
GLOD4_HUMAN_288 17 288 304 LLDDAMAADKSDEWFAK PRIDE
GLOD4_HUMAN_96 20 96 115 LGNDFMGITLASSQAVSNAR PRIDE
PAp00000536 18 173 190 ALLGYADNQCKLELQGVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved