AutismKB 2.0

Annotation Detail for FAM135B


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Basic Information Top
Gene Symbol:FAM135B ( C8ORFK32,MGC126009,MGC126010,MGC33221 )
Gene Full Name: family with sequence similarity 135, member B
Band: 8q24.23
Quick LinksEntrez ID:51059; OMIM: NA; Uniprot ID:F135B_HUMAN; ENSEMBL ID: ENSG00000147724; HGNC ID: 28029
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult9 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal44 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain11 / 11009899
cervix0 / 481710 
connective tissue0 / 1492550 
ear1 / 1621261
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis17 / 33044251
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P68097
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.5 ± 0.63
Basal Forebrain5.1 ± 0.59
Basal Part of Pons6.68 ± 0.15
Cerebellar Cortex6.25 ± 0.14
Cerebellar Nuclei5.88 ± 0.51
Claustrum4.57 ± 0.72
Epithalamus5.89 ± 0.63
Frontal Lobe6.12 ± 0.46
Globus Pallidus4.38 ± 0.6
Hypothalamus5.15 ± 0.73
Insula5.92 ± 0.32
Limbic Lobe5.82 ± 0.66
Mesencephalon5.82 ± 0.67
Myelencephalon5.73 ± 0.72
Occipital Lobe5.43 ± 0.74
Parietal Lobe6.06 ± 0.48
Pontine Tegmentum5.65 ± 0.68
Striatum5.3 ± 0.64
Subthalamus6.91 ± 0.41
Temporal Lobe5.9 ± 0.38
Thalamus6 ± 0.52
White Matter3.27 ± 0.57
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1700010C24RikCBCerebellum14.75
18.42
1700010C24RikCTXCerebral cortex15.93
13.57
1700010C24RikHIPHippocampal region18.81
33.68
1700010C24RikHPFHippocampal formation21.48
28.2
1700010C24RikHYHypothalamus0.69
0.79
1700010C24RikLSXLateral septal complex3.05
2.65
1700010C24RikMBMidbrain1.75
2.28
1700010C24RikMYMedulla5.87
9.94
1700010C24RikOLFOlfactory bulb16.31
13.74
1700010C24RikPPons4.72
6.51
1700010C24RikPALPallidum1.1
0.89
1700010C24RikRHPRetrohippocampal region24.18
24.02
1700010C24RiksAMYStriatum-like amygdalar nuclei0.44
0.38
1700010C24RikSTRStriatum2.02
1.63
1700010C24RikSTRdStriatum dorsal region0.87
0.59
1700010C24RikSTRvStriatum ventral region5.1
3.92
1700010C24RikTHThalamus0.32
0.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018