AutismKB 2.0

Annotation Detail for TXNDC11


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Basic Information Top
Gene Symbol:TXNDC11 ( EFP1 )
Gene Full Name: thioredoxin domain containing 11
Band: 16p13.13
Quick LinksEntrez ID:51061; OMIM: NA; Uniprot ID:TXD11_HUMAN; ENSEMBL ID: ENSG00000153066; HGNC ID: 28030
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus13 / 56401223
neonate2 / 3109764
infant0 / 236200 
juvenile7 / 55556125
adult74 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor10 / 26384537
glioma7 / 10688365
head and neck tumor8 / 13630258
kidney tumor4 / 6895958
leukemia3 / 9584231
liver tumor11 / 96359114
lung tumor5 / 10312748
lymphoma7 / 7175597
non-neoplasia7 / 9725071
normal100 / 336030729
ovarian tumor4 / 7668252
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites3 / 4001574
bladder0 / 297570 
blood3 / 12347824
bone2 / 7165527
bone marrow8 / 48801163
brain28 / 110098925
cervix1 / 4817120
connective tissue15 / 149255100
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye12 / 21105456
heart1 / 8962611
intestine11 / 23447246
kidney8 / 21177737
larynx1 / 2414541
liver15 / 20774372
lung22 / 33697465
lymph4 / 4427090
lymph node7 / 9161076
mammary gland6 / 15327139
mouth7 / 67052104
muscle2 / 10771518
nerve1 / 1576863
ovary5 / 10205148
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate7 / 18934536
salivary gland1 / 2015549
skin4 / 21057418
spleen2 / 5395237
stomach1 / 9661910
testis16 / 33044248
thymus4 / 8113149
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord1 / 1368073
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P282031
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.09 ± 0.46
Basal Forebrain5.02 ± 0.25
Basal Part of Pons4.56 ± 0.57
Cerebellar Cortex4.92 ± 0.34
Cerebellar Nuclei4.22 ± 0.53
Claustrum5.13 ± 0.54
Epithalamus4.64 ± 0.54
Frontal Lobe4.44 ± 0.53
Globus Pallidus4.59 ± 0.5
Hypothalamus4.27 ± 0.49
Insula4.46 ± 0.27
Limbic Lobe4.81 ± 0.5
Mesencephalon4.75 ± 0.54
Myelencephalon4.65 ± 0.5
Occipital Lobe5.13 ± 0.44
Parietal Lobe4.67 ± 0.47
Pontine Tegmentum4.66 ± 0.59
Striatum5.11 ± 0.44
Subthalamus4.14 ± 0.73
Temporal Lobe4.57 ± 0.54
Thalamus4.79 ± 0.42
White Matter5.04 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Txndc11CBCerebellum23.24
31.07
Txndc11CTXCerebral cortex48.02
35.96
Txndc11HIPHippocampal region40.07
42.43
Txndc11HPFHippocampal formation43.41
40.89
Txndc11HYHypothalamus39.66
29.74
Txndc11LSXLateral septal complex20.36
14.13
Txndc11MBMidbrain21.32
19.28
Txndc11MYMedulla18.86
21.54
Txndc11OLFOlfactory bulb56.8
48.35
Txndc11PPons21.48
22.56
Txndc11PALPallidum27.35
23.54
Txndc11RHPRetrohippocampal region52.68
40.82
Txndc11sAMYStriatum-like amygdalar nuclei51.62
36.95
Txndc11STRStriatum24.32
16.86
Txndc11STRdStriatum dorsal region17.16
11.45
Txndc11STRvStriatum ventral region34.65
23.66
Txndc11THThalamus29.33
22.64
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018