AutismKB 2.0

Annotation Detail for RPS27L


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RPS27L ( - )
Gene Full Name: ribosomal protein S27-like
Band: 15q22.2
Quick LinksEntrez ID:51065; OMIM: 612055; Uniprot ID:RS27L_HUMAN; ENSEMBL ID: ENSG00000185088; HGNC ID: 18476
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst2 / 6231932
fetus33 / 56401258
neonate5 / 31097160
infant1 / 2362042
juvenile3 / 5555653
adult172 / 193912188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma5 / 17475286
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor10 / 26384537
glioma23 / 106883215
head and neck tumor2 / 13630214
kidney tumor4 / 6895958
leukemia11 / 95842114
liver tumor10 / 96359103
lung tumor20 / 103127193
lymphoma1 / 7175513
non-neoplasia8 / 9725082
normal313 / 336030793
ovarian tumor28 / 76682365
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer15 / 102680146
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland5 / 33197150
ascites3 / 4001574
bladder7 / 29757235
blood13 / 123478105
bone2 / 7165527
bone marrow15 / 48801307
brain37 / 110098933
cervix0 / 481710 
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye10 / 21105447
heart22 / 89626245
intestine5 / 23447221
kidney25 / 211777118
larynx0 / 241450 
liver39 / 207743187
lung31 / 33697491
lymph0 / 442700 
lymph node3 / 9161032
mammary gland20 / 153271130
mouth36 / 67052536
muscle11 / 107715102
nerve1 / 1576863
ovary29 / 102051284
pancreas5 / 21481223
parathyroid15 / 20539730
pharynx2 / 4132848
pituitary gland5 / 16585301
placenta8 / 28082528
prostate27 / 189345142
salivary gland2 / 2015599
skin39 / 210574185
spleen0 / 539520 
stomach4 / 9661941
testis21 / 33044263
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord3 / 13680219
uterus11 / 23287847
vascular10 / 51780193
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218007_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1636.85
Adipocyte2343.2
AdrenalCortex647.55
Adrenalgland611.05
Amygdala183.2
Appendix426.6
AtrioventricularNode266.65
BDCA4+_DentriticCells841.75
Bonemarrow264.55
BronchialEpithelialCells1246.95
CD105+_Endothelial1278.1
CD14+_Monocytes942.65
CD19+_BCells(neg._sel.)1077.6
CD33+_Myeloid889.85
CD34+1548.5
CD4+_Tcells917.15
CD56+_NKCells1139.5
CD71+_EarlyErythroid553.7
CD8+_Tcells766.55
CardiacMyocytes1850.35
Caudatenucleus183
Cerebellum83.5
CerebellumPeduncles149.35
CiliaryGanglion128.25
CingulateCortex187.5
Colorectaladenocarcinoma227.1
DorsalRootGanglion216.75
FetalThyroid473.25
Fetalbrain116.9
Fetalliver326.85
Fetallung438.3
GlobusPallidus112.15
Heart117.85
Hypothalamus411.25
Kidney551.9
Leukemia_chronicMyelogenousK-562544.5
Leukemia_promyelocytic-HL-60890.55
Leukemialymphoblastic(MOLT-4)377.55
Liver73.9
Lung505.7
Lymphnode496.85
Lymphoma_burkitts(Daudi)1272.65
Lymphoma_burkitts(Raji)416.4
MedullaOblongata113.6
OccipitalLobe130.5
OlfactoryBulb648.1
Ovary279.1
Pancreas479.9
PancreaticIslet999.7
ParietalLobe131.3
Pituitary708.95
Placenta533.05
Pons157.4
PrefrontalCortex430.75
Prostate826.8
Salivarygland902.8
SkeletalMuscle176.3
Skin214.25
SmoothMuscle4008.7
Spinalcord423.1
SubthalamicNucleus195.4
SuperiorCervicalGanglion71.75
TemporalLobe176.9
Testis146.2
TestisGermCell292.35
TestisIntersitial176.3
TestisLeydigCell293.15
TestisSeminiferousTubule249.65
Thalamus307.2
Thymus442.75
Thyroid649.6
Tongue483
Tonsil432.7
Trachea479.65
TrigeminalGanglion249.8
Uterus457.05
UterusCorpus984.45
WholeBlood554.05
Wholebrain197
colon1244.95
pineal_day544.6
pineal_night534.1
retina745.2
small_intestine1110.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9218_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.14 ± 0.45
Basal Forebrain6.34 ± 0.29
Basal Part of Pons6.03 ± 0.34
Cerebellar Cortex6.26 ± 0.21
Cerebellar Nuclei6.36 ± 0.45
Claustrum5.89 ± 0.47
Epithalamus6.65 ± 0.41
Frontal Lobe6.39 ± 0.32
Globus Pallidus7.3 ± 0.21
Hypothalamus6.77 ± 0.4
Insula6.42 ± 0.24
Limbic Lobe6.11 ± 0.37
Mesencephalon6.49 ± 0.32
Myelencephalon6.31 ± 0.38
Occipital Lobe6.02 ± 0.4
Parietal Lobe6.3 ± 0.29
Pontine Tegmentum6.5 ± 0.34
Striatum6.49 ± 0.34
Subthalamus6.75 ± 0.15
Temporal Lobe6.24 ± 0.34
Thalamus6.41 ± 0.3
White Matter7.13 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rps27lCBCerebellum0.77
1.6
Rps27lCTXCerebral cortex0.76
0.87
Rps27lHIPHippocampal region0.9
1.11
Rps27lHPFHippocampal formation0.69
0.95
Rps27lHYHypothalamus0.07
0.06
Rps27lLSXLateral septal complex0.16
0.12
Rps27lMBMidbrain0.21
0.35
Rps27lMYMedulla0.83
0.99
Rps27lOLFOlfactory bulb0.72
1.5
Rps27lPPons0.3
0.46
Rps27lPALPallidum0.23
0.25
Rps27lRHPRetrohippocampal region0.37
0.75
Rps27lsAMYStriatum-like amygdalar nuclei0.43
0.43
Rps27lSTRStriatum0.39
0.42
Rps27lSTRdStriatum dorsal region0.36
0.39
Rps27lSTRvStriatum ventral region0.49
0.59
Rps27lTHThalamus0.55
0.61
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000678 10 71 80 ARLTEGCSFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved