AutismKB 2.0

Annotation Detail for DERA


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Basic Information Top
Gene Symbol:DERA ( DEOC )
Gene Full Name: deoxyribose-phosphate aldolase (putative)
Band: 12p12.3
Quick LinksEntrez ID:51071; OMIM: NA; Uniprot ID:DEOC_HUMAN; ENSEMBL ID: ENSG00000023697; HGNC ID: 24269
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult103 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma6 / 17475343
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma8 / 8282396
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor22 / 26384583
glioma14 / 106883130
head and neck tumor2 / 13630214
kidney tumor4 / 6895958
leukemia4 / 9584241
liver tumor9 / 9635993
lung tumor0 / 1031270 
lymphoma8 / 71755111
non-neoplasia1 / 9725010
normal149 / 336030744
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer2 / 10268019
retinoblastoma3 / 4635664
skin tumor9 / 12494972
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites2 / 4001549
bladder6 / 29757201
blood4 / 12347832
bone10 / 71655139
bone marrow6 / 48801122
brain43 / 110098939
cervix3 / 4817162
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine12 / 23447251
kidney16 / 21177775
larynx0 / 241450 
liver24 / 207743115
lung13 / 33697438
lymph0 / 442700 
lymph node10 / 91610109
mammary gland8 / 15327152
mouth2 / 6705229
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas2 / 2148129
parathyroid3 / 20539146
pharynx4 / 4132896
pituitary gland2 / 16585120
placenta10 / 28082535
prostate3 / 18934515
salivary gland1 / 2015549
skin11 / 21057452
spleen1 / 5395218
stomach2 / 9661920
testis20 / 33044260
thymus0 / 811310 
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218102_at
Cell line Expression level Expression bar
721_B_lymphoblasts210.75
Adipocyte42.7
AdrenalCortex17.1
Adrenalgland15.95
Amygdala19.4
Appendix19.25
AtrioventricularNode13.1
BDCA4+_DentriticCells101.45
Bonemarrow14.5
BronchialEpithelialCells197.25
CD105+_Endothelial59.05
CD14+_Monocytes72.45
CD19+_BCells(neg._sel.)33.95
CD33+_Myeloid75.45
CD34+112.55
CD4+_Tcells16.25
CD56+_NKCells79.6
CD71+_EarlyErythroid29.25
CD8+_Tcells14.5
CardiacMyocytes17.05
Caudatenucleus16.8
Cerebellum11.75
CerebellumPeduncles19.25
CiliaryGanglion13.45
CingulateCortex15.3
Colorectaladenocarcinoma64.25
DorsalRootGanglion15.7
FetalThyroid80.5
Fetalbrain14.75
Fetalliver101.35
Fetallung38.1
GlobusPallidus10.4
Heart19.6
Hypothalamus23.6
Kidney81.3
Leukemia_chronicMyelogenousK-56211.7
Leukemia_promyelocytic-HL-6018.3
Leukemialymphoblastic(MOLT-4)23.5
Liver140.15
Lung52.25
Lymphnode23.8
Lymphoma_burkitts(Daudi)135.2
Lymphoma_burkitts(Raji)56.75
MedullaOblongata16.35
OccipitalLobe12.8
OlfactoryBulb56.1
Ovary7.85
Pancreas59.6
PancreaticIslet39.45
ParietalLobe17.45
Pituitary18.95
Placenta30.45
Pons15.85
PrefrontalCortex19.9
Prostate20.05
Salivarygland18.85
SkeletalMuscle24.5
Skin13.2
SmoothMuscle62.45
Spinalcord67.25
SubthalamicNucleus15.3
SuperiorCervicalGanglion23.35
TemporalLobe15
Testis13.4
TestisGermCell13.15
TestisIntersitial13.55
TestisLeydigCell16.7
TestisSeminiferousTubule9.8
Thalamus16.85
Thymus21.8
Thyroid157.2
Tongue38.7
Tonsil19.1
Trachea16
TrigeminalGanglion20.1
Uterus47.75
UterusCorpus26.65
WholeBlood60.55
Wholebrain14.7
colon155.85
pineal_day22.82
pineal_night23.04
retina29.95
small_intestine121.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9281_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.27 ± 0.45
Basal Forebrain4.45 ± 0.35
Basal Part of Pons4.53 ± 0.28
Cerebellar Cortex4.23 ± 0.38
Cerebellar Nuclei4.23 ± 0.47
Claustrum4.43 ± 0.68
Epithalamus4.93 ± 0.45
Frontal Lobe4.42 ± 0.51
Globus Pallidus5.52 ± 0.36
Hypothalamus4.48 ± 0.44
Insula4.31 ± 0.32
Limbic Lobe4.25 ± 0.66
Mesencephalon4.44 ± 0.64
Myelencephalon4.47 ± 0.5
Occipital Lobe4.36 ± 0.48
Parietal Lobe4.39 ± 0.58
Pontine Tegmentum4.52 ± 0.54
Striatum4.59 ± 0.42
Subthalamus4.41 ± 0.18
Temporal Lobe4.41 ± 0.46
Thalamus4.72 ± 0.43
White Matter6.12 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
DeraCBCerebellum0.52
1.02
DeraCTXCerebral cortex0.74
0.99
DeraHIPHippocampal region2.01
2.82
DeraHPFHippocampal formation1.6
2
DeraHYHypothalamus1.24
1.27
DeraLSXLateral septal complex0.03
0
DeraMBMidbrain0.55
0.81
DeraMYMedulla0.16
0.35
DeraOLFOlfactory bulb1.04
1.82
DeraPPons2.06
3.39
DeraPALPallidum1.14
0.94
DeraRHPRetrohippocampal region0.82
0.76
DerasAMYStriatum-like amygdalar nuclei1.11
1.02
DeraSTRStriatum0.46
0.45
DeraSTRdStriatum dorsal region0.38
0.39
DeraSTRvStriatum ventral region0.36
0.29
DeraTHThalamus1.3
0.96
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DEOC_HUMAN_114 23 114 136 AAGCNIPVASVAAGFPAGQTHLK PRIDE
DEOC_HUMAN_224 15 224 238 ETVNATFPVAIVMLR PRIDE
DEOC_HUMAN_263 24 263 286 DSLAWLSLVKEELGDEWLKPELFR PRIDE
PAp00000152 23 115 137 AAGCNIPVASVAAGFPAGQTHLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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