AutismKB 2.0

Annotation Detail for MRPL4


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Basic Information Top
Gene Symbol:MRPL4 ( CGI-28,L4mt,MGC16367,MGC2681 )
Gene Full Name: mitochondrial ribosomal protein L4
Band: 19p13.2
Quick LinksEntrez ID:51073; OMIM: 611823; Uniprot ID:RM04_HUMAN; ENSEMBL ID: ENSG00000105364; HGNC ID: 14276
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst7 / 62319112
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile8 / 55556143
adult137 / 193912170
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor11 / 94178116
cervical tumor3 / 3436687
chondrosarcoma5 / 8282360
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor22 / 119369184
germ cell tumor19 / 26384572
glioma10 / 10688393
head and neck tumor1 / 1363027
kidney tumor8 / 68959116
leukemia15 / 95842156
liver tumor5 / 9635951
lung tumor16 / 103127155
lymphoma16 / 71755222
non-neoplasia0 / 972500 
normal119 / 336030735
ovarian tumor8 / 76682104
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS40 / 125680318
prostate cancer12 / 102680116
retinoblastoma7 / 46356151
skin tumor23 / 124949184
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites7 / 40015174
bladder1 / 2975733
blood15 / 123478121
bone7 / 7165597
bone marrow1 / 4880120
brain36 / 110098932
cervix5 / 48171103
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus1 / 2020949
eye18 / 21105485
heart0 / 896260 
intestine16 / 23447268
kidney11 / 21177751
larynx0 / 241450 
liver6 / 20774328
lung27 / 33697480
lymph12 / 44270271
lymph node5 / 9161054
mammary gland19 / 153271123
mouth0 / 670520 
muscle7 / 10771564
nerve0 / 157680 
ovary13 / 102051127
pancreas13 / 21481260
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta16 / 28082556
prostate14 / 18934573
salivary gland0 / 201550 
skin31 / 210574147
spleen1 / 5395218
stomach14 / 96619144
testis3 / 3304429
thymus1 / 8113112
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218105_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts344.85
Adipocyte15
AdrenalCortex15.15
Adrenalgland15.2
Amygdala16
Appendix14.2
AtrioventricularNode11.4
BDCA4+_DentriticCells18.2
Bonemarrow15
BronchialEpithelialCells26.55
CD105+_Endothelial23.65
CD14+_Monocytes17.95
CD19+_BCells(neg._sel.)16.75
CD33+_Myeloid19.5
CD34+34.95
CD4+_Tcells16.2
CD56+_NKCells18.25
CD71+_EarlyErythroid12.75
CD8+_Tcells14.45
CardiacMyocytes18.9
Caudatenucleus18.4
Cerebellum15.65
CerebellumPeduncles19.2
CiliaryGanglion10.55
CingulateCortex15.4
Colorectaladenocarcinoma38.95
DorsalRootGanglion11.65
FetalThyroid17.9
Fetalbrain15.3
Fetalliver12.05
Fetallung13.05
GlobusPallidus11.1
Heart45.65
Hypothalamus17.2
Kidney15.2
Leukemia_chronicMyelogenousK-56244.05
Leukemia_promyelocytic-HL-60123.5
Leukemialymphoblastic(MOLT-4)26.4
Liver40.75
Lung22.75
Lymphnode13.45
Lymphoma_burkitts(Daudi)91.2
Lymphoma_burkitts(Raji)73.5
MedullaOblongata17
OccipitalLobe14
OlfactoryBulb12.2
Ovary9.95
Pancreas11.8
PancreaticIslet16.05
ParietalLobe17.8
Pituitary17.5
Placenta14.2
Pons16.2
PrefrontalCortex18.85
Prostate19.2
Salivarygland11.1
SkeletalMuscle16.9
Skin11.55
SmoothMuscle17.6
Spinalcord16.25
SubthalamicNucleus13.85
SuperiorCervicalGanglion16.7
TemporalLobe17.5
Testis13.6
TestisGermCell12.5
TestisIntersitial11.6
TestisLeydigCell14.9
TestisSeminiferousTubule12.85
Thalamus15.85
Thymus17.05
Thyroid26.05
Tongue14.8
Tonsil16.2
Trachea12.55
TrigeminalGanglion15.05
Uterus12.05
UterusCorpus12.65
WholeBlood13.4
Wholebrain28
colon15.8
pineal_day17.68
pineal_night17.02
retina20.225
small_intestine14.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4675_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.7 ± 0.41
Basal Forebrain5.05 ± 0.49
Basal Part of Pons6.1 ± 0.21
Cerebellar Cortex5.47 ± 0.47
Cerebellar Nuclei5.18 ± 0.71
Claustrum5.37 ± 0.8
Epithalamus4.9 ± 0.34
Frontal Lobe5.73 ± 0.41
Globus Pallidus4.85 ± 0.52
Hypothalamus5.11 ± 0.57
Insula5.55 ± 0.31
Limbic Lobe5.54 ± 0.41
Mesencephalon5.32 ± 0.59
Myelencephalon5.39 ± 0.45
Occipital Lobe5.1 ± 0.44
Parietal Lobe5.49 ± 0.42
Pontine Tegmentum5.41 ± 0.37
Striatum5.22 ± 0.39
Subthalamus5.65 ± 0.18
Temporal Lobe5.56 ± 0.44
Thalamus5.41 ± 0.45
White Matter4.81 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mrpl4CBCerebellum0
0
Mrpl4CTXCerebral cortex0
0
Mrpl4HIPHippocampal region0
0
Mrpl4HPFHippocampal formation0
0
Mrpl4HYHypothalamus0
0
Mrpl4LSXLateral septal complex0
0
Mrpl4MBMidbrain0
0
Mrpl4MYMedulla0
0
Mrpl4OLFOlfactory bulb0
0
Mrpl4PPons0
0
Mrpl4PALPallidum0
0
Mrpl4RHPRetrohippocampal region0
0
Mrpl4sAMYStriatum-like amygdalar nuclei0
0
Mrpl4STRStriatum0
0
Mrpl4STRdStriatum dorsal region0
0
Mrpl4STRvStriatum ventral region0
0
Mrpl4THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00038662 16 77 92 VGLADLHPDVFATAPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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