AutismKB 2.0

Annotation Detail for PCM1


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Basic Information Top
Gene Symbol:PCM1 ( PTC4 )
Gene Full Name: pericentriolar material 1
Band: 8p22
Quick LinksEntrez ID:5108; OMIM: 600299; Uniprot ID:PCM1_HUMAN; ENSEMBL ID: ENSG00000078674; HGNC ID: 8727
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst10 / 62319160
fetus74 / 564012131
neonate0 / 310970 
infant2 / 2362084
juvenile7 / 55556125
adult192 / 193912199
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor7 / 34366203
chondrosarcoma3 / 8282336
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor16 / 119369134
germ cell tumor29 / 263845109
glioma3 / 10688328
head and neck tumor15 / 136302110
kidney tumor5 / 6895972
leukemia14 / 95842146
liver tumor14 / 96359145
lung tumor8 / 10312777
lymphoma4 / 7175555
non-neoplasia7 / 9725071
normal309 / 336030791
ovarian tumor2 / 7668226
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer5 / 10268048
retinoblastoma3 / 4635664
skin tumor6 / 12494948
soft tissue/muscle tissue tumor15 / 125191119
uterine tumor16 / 90257177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites2 / 4001549
bladder1 / 2975733
blood12 / 12347897
bone6 / 7165583
bone marrow7 / 48801143
brain74 / 110098967
cervix7 / 48171145
connective tissue11 / 14925573
ear1 / 1621261
embryonic tissue20 / 21572292
esophagus1 / 2020949
eye11 / 21105452
heart15 / 89626167
intestine12 / 23447251
kidney20 / 21177794
larynx1 / 2414541
liver20 / 20774396
lung33 / 33697497
lymph2 / 4427045
lymph node14 / 91610152
mammary gland20 / 153271130
mouth8 / 67052119
muscle13 / 107715120
nerve1 / 1576863
ovary3 / 10205129
pancreas15 / 21481269
parathyroid1 / 2053948
pharynx5 / 41328120
pituitary gland1 / 1658560
placenta17 / 28082560
prostate12 / 18934563
salivary gland1 / 2015549
skin6 / 21057428
spleen3 / 5395255
stomach16 / 96619165
testis76 / 330442229
thymus9 / 81131110
thyroid5 / 47473105
tonsil0 / 169990 
trachea10 / 52413190
umbilical cord0 / 136800 
uterus34 / 232878145
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214937_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts326.4
Adipocyte27.3
AdrenalCortex42.6
Adrenalgland16.25
Amygdala47.75
Appendix33.35
AtrioventricularNode23.45
BDCA4+_DentriticCells187.5
Bonemarrow11.45
BronchialEpithelialCells21.9
CD105+_Endothelial269.1
CD14+_Monocytes53.65
CD19+_BCells(neg._sel.)107.15
CD33+_Myeloid70.1
CD34+322.1
CD4+_Tcells264.85
CD56+_NKCells150
CD71+_EarlyErythroid185.2
CD8+_Tcells278.9
CardiacMyocytes33.4
Caudatenucleus66.35
Cerebellum15.45
CerebellumPeduncles27.35
CiliaryGanglion16.5
CingulateCortex30.1
Colorectaladenocarcinoma51.5
DorsalRootGanglion21.1
FetalThyroid32.4
Fetalbrain86.3
Fetalliver53.75
Fetallung61.9
GlobusPallidus25.9
Heart10.75
Hypothalamus75.9
Kidney14.7
Leukemia_chronicMyelogenousK-56287.45
Leukemia_promyelocytic-HL-6091.75
Leukemialymphoblastic(MOLT-4)158.5
Liver25.9
Lung6.4
Lymphnode84.45
Lymphoma_burkitts(Daudi)101.05
Lymphoma_burkitts(Raji)34.1
MedullaOblongata54.3
OccipitalLobe70.1
OlfactoryBulb59.75
Ovary36.4
Pancreas19.75
PancreaticIslet126.4
ParietalLobe58.6
Pituitary95.9
Placenta14.35
Pons20.9
PrefrontalCortex113.9
Prostate34.8
Salivarygland47.2
SkeletalMuscle35.3
Skin22.2
SmoothMuscle41.1
Spinalcord67.9
SubthalamicNucleus27.4
SuperiorCervicalGanglion29.35
TemporalLobe21.1
Testis37.4
TestisGermCell413.2
TestisIntersitial338.2
TestisLeydigCell234.4
TestisSeminiferousTubule267.25
Thalamus48.35
Thymus21.1
Thyroid89.55
Tongue29.05
Tonsil66.6
Trachea46.4
TrigeminalGanglion47.65
Uterus87.75
UterusCorpus22.35
WholeBlood50.85
Wholebrain8.9
colon21.95
pineal_day248.62
pineal_night215.1
retina53.45
small_intestine15.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P555510
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.91 ± 0.32
Basal Forebrain7.9 ± 0.26
Basal Part of Pons7.8 ± 0.22
Cerebellar Cortex8.03 ± 0.18
Cerebellar Nuclei7.39 ± 0.23
Claustrum7.72 ± 0.33
Epithalamus7.82 ± 0.28
Frontal Lobe7.91 ± 0.25
Globus Pallidus7.41 ± 0.18
Hypothalamus7.75 ± 0.34
Insula8.06 ± 0.24
Limbic Lobe7.83 ± 0.35
Mesencephalon7.83 ± 0.28
Myelencephalon7.82 ± 0.26
Occipital Lobe7.71 ± 0.33
Parietal Lobe7.89 ± 0.28
Pontine Tegmentum7.89 ± 0.29
Striatum8 ± 0.33
Subthalamus7.93 ± 0.24
Temporal Lobe7.84 ± 0.25
Thalamus7.78 ± 0.25
White Matter7.7 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pcm1CBCerebellum46.78
65.6
Pcm1CTXCerebral cortex95.2
80.12
Pcm1HIPHippocampal region47.47
82.63
Pcm1HPFHippocampal formation62.33
81.36
Pcm1HYHypothalamus33.87
29.61
Pcm1LSXLateral septal complex96.31
78.94
Pcm1MBMidbrain61.22
61.57
Pcm1MYMedulla56.32
65.92
Pcm1OLFOlfactory bulb72.01
63.64
Pcm1PPons46.25
52.33
Pcm1PALPallidum40.55
39.58
Pcm1RHPRetrohippocampal region88.55
82.56
Pcm1sAMYStriatum-like amygdalar nuclei60.57
48.13
Pcm1STRStriatum61.28
48.23
Pcm1STRdStriatum dorsal region60.56
48.28
Pcm1STRvStriatum ventral region58.24
43.05
Pcm1THThalamus70.65
69.46
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007460 16 1572 1587 SSQQPVSEVSTIPCPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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