AutismKB 2.0

Annotation Detail for SCCPDH


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Basic Information Top
Gene Symbol:SCCPDH ( FLJ43187,NET11,RP11-439E19.2 )
Gene Full Name: saccharopine dehydrogenase (putative)
Band: 1q44
Quick LinksEntrez ID:51097; OMIM: NA; Uniprot ID:SCPDH_HUMAN; ENSEMBL ID: ENSG00000143653; HGNC ID: 24275
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus60 / 564012106
neonate0 / 310970 
infant2 / 2362084
juvenile8 / 55556143
adult173 / 193912189
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor16 / 26384560
glioma7 / 10688365
head and neck tumor9 / 13630266
kidney tumor9 / 68959130
leukemia7 / 9584273
liver tumor10 / 96359103
lung tumor11 / 103127106
lymphoma3 / 7175541
non-neoplasia4 / 9725041
normal294 / 336030787
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer12 / 102680116
retinoblastoma4 / 4635686
skin tumor16 / 124949128
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland5 / 33197150
ascites8 / 40015199
bladder2 / 2975767
blood7 / 12347856
bone10 / 71655139
bone marrow2 / 4880140
brain108 / 110098998
cervix3 / 4817162
connective tissue9 / 14925560
ear1 / 1621261
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye20 / 21105494
heart9 / 89626100
intestine14 / 23447259
kidney26 / 211777122
larynx0 / 241450 
liver27 / 207743129
lung24 / 33697471
lymph0 / 442700 
lymph node2 / 9161021
mammary gland6 / 15327139
mouth9 / 67052134
muscle1 / 1077159
nerve2 / 15768126
ovary7 / 10205168
pancreas8 / 21481237
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta24 / 28082585
prostate21 / 189345110
salivary gland0 / 201550 
skin20 / 21057494
spleen0 / 539520 
stomach3 / 9661931
testis76 / 330442229
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus15 / 23287864
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201826_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.95
Adipocyte10
AdrenalCortex9.1
Adrenalgland24
Amygdala17.55
Appendix8.3
AtrioventricularNode7.3
BDCA4+_DentriticCells6.35
Bonemarrow7.25
BronchialEpithelialCells5.05
CD105+_Endothelial9.25
CD14+_Monocytes7.65
CD19+_BCells(neg._sel.)5.45
CD33+_Myeloid11.2
CD34+23.55
CD4+_Tcells3.7
CD56+_NKCells4.8
CD71+_EarlyErythroid6.5
CD8+_Tcells3.8
CardiacMyocytes7.3
Caudatenucleus9.6
Cerebellum7.25
CerebellumPeduncles10.45
CiliaryGanglion4.2
CingulateCortex14.25
Colorectaladenocarcinoma8.85
DorsalRootGanglion7.5
FetalThyroid8.9
Fetalbrain10.5
Fetalliver14.4
Fetallung6.9
GlobusPallidus6.8
Heart10.9
Hypothalamus43.1
Kidney7.7
Leukemia_chronicMyelogenousK-5628.1
Leukemia_promyelocytic-HL-605.75
Leukemialymphoblastic(MOLT-4)10.45
Liver13.05
Lung10
Lymphnode4.85
Lymphoma_burkitts(Daudi)10.2
Lymphoma_burkitts(Raji)6
MedullaOblongata13.3
OccipitalLobe14.25
OlfactoryBulb40.65
Ovary6
Pancreas5.85
PancreaticIslet8.55
ParietalLobe11.65
Pituitary13.75
Placenta12.2
Pons8.7
PrefrontalCortex14.45
Prostate56.6
Salivarygland7.2
SkeletalMuscle8.25
Skin2.95
SmoothMuscle8.95
Spinalcord67.05
SubthalamicNucleus8.85
SuperiorCervicalGanglion10.1
TemporalLobe8.65
Testis18.1
TestisGermCell9.05
TestisIntersitial7.85
TestisLeydigCell9.1
TestisSeminiferousTubule11.25
Thalamus33.15
Thymus5.8
Thyroid12.95
Tongue6.85
Tonsil6.3
Trachea7.85
TrigeminalGanglion8.15
Uterus8.05
UterusCorpus4.9
WholeBlood6.05
Wholebrain19.5
colon9.25
pineal_day35.46
pineal_night34.84
retina24.325
small_intestine9.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7652_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.43 ± 0.22
Basal Forebrain8.49 ± 0.29
Basal Part of Pons8.63 ± 0.19
Cerebellar Cortex8.28 ± 0.16
Cerebellar Nuclei8.86 ± 0.56
Claustrum8.29 ± 0.39
Epithalamus8.83 ± 0.31
Frontal Lobe8.56 ± 0.3
Globus Pallidus8.88 ± 0.24
Hypothalamus8.9 ± 0.23
Insula8.53 ± 0.22
Limbic Lobe8.34 ± 0.3
Mesencephalon8.6 ± 0.37
Myelencephalon8.47 ± 0.37
Occipital Lobe8.19 ± 0.38
Parietal Lobe8.41 ± 0.32
Pontine Tegmentum8.48 ± 0.24
Striatum8.24 ± 0.32
Subthalamus8.7 ± 0.22
Temporal Lobe8.55 ± 0.3
Thalamus8.43 ± 0.28
White Matter9.89 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
SccpdhCBCerebellum6.67
9.89
SccpdhCTXCerebral cortex2.16
2.22
SccpdhHIPHippocampal region0.24
0.25
SccpdhHPFHippocampal formation0.38
0.41
SccpdhHYHypothalamus0.28
0.21
SccpdhLSXLateral septal complex0.06
0.07
SccpdhMBMidbrain0.93
0.86
SccpdhMYMedulla3.09
3.31
SccpdhOLFOlfactory bulb0.53
0.42
SccpdhPPons2.79
2.75
SccpdhPALPallidum0.42
0.4
SccpdhRHPRetrohippocampal region0.61
0.61
SccpdhsAMYStriatum-like amygdalar nuclei0.87
0.92
SccpdhSTRStriatum0.38
0.39
SccpdhSTRdStriatum dorsal region0.4
0.41
SccpdhSTRvStriatum ventral region0.18
0.15
SccpdhTHThalamus0.28
0.4
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00026486 28 63 90 LGRPTLSSEVGIIICDIANPASLDEMAK Peptide Atlas
SCPDH_HUMAN_365 29 365 393 GPEAGYVATPIAMVQAAMTLLSDASHLPK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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