AutismKB 2.0

Annotation Detail for LACTB2


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Basic Information Top
Gene Symbol:LACTB2 ( - )
Gene Full Name: lactamase, beta 2
Band: 8q13.3
Quick LinksEntrez ID:51110; OMIM: NA; Uniprot ID:LACB2_HUMAN; ENSEMBL ID: ENSG00000147592; HGNC ID: 18512
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma4 / 17475228
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor7 / 13630251
kidney tumor7 / 68959101
leukemia4 / 9584241
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal84 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder4 / 29757134
blood0 / 1234780 
bone0 / 716550 
bone marrow3 / 4880161
brain15 / 110098913
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye14 / 21105466
heart2 / 8962622
intestine4 / 23447217
kidney15 / 21177770
larynx1 / 2414541
liver5 / 20774324
lung6 / 33697417
lymph0 / 442700 
lymph node2 / 9161021
mammary gland5 / 15327132
mouth6 / 6705289
muscle6 / 10771555
nerve0 / 157680 
ovary0 / 1020510 
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta6 / 28082521
prostate1 / 1893455
salivary gland8 / 20155396
skin3 / 21057414
spleen0 / 539520 
stomach1 / 9661910
testis21 / 33044263
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218701_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.05
Adipocyte6.65
AdrenalCortex7.2
Adrenalgland5.8
Amygdala11.45
Appendix7
AtrioventricularNode5.65
BDCA4+_DentriticCells7.1
Bonemarrow6.55
BronchialEpithelialCells6
CD105+_Endothelial6.5
CD14+_Monocytes7.05
CD19+_BCells(neg._sel.)6.4
CD33+_Myeloid8.45
CD34+8.45
CD4+_Tcells6.5
CD56+_NKCells7.35
CD71+_EarlyErythroid5.95
CD8+_Tcells5.75
CardiacMyocytes9
Caudatenucleus5.65
Cerebellum5
CerebellumPeduncles7.25
CiliaryGanglion5.1
CingulateCortex6.55
Colorectaladenocarcinoma6.5
DorsalRootGanglion5.45
FetalThyroid6.2
Fetalbrain5.95
Fetalliver5.55
Fetallung4.9
GlobusPallidus4.95
Heart8.95
Hypothalamus6.85
Kidney6.25
Leukemia_chronicMyelogenousK-5625.7
Leukemia_promyelocytic-HL-605.45
Leukemialymphoblastic(MOLT-4)4.75
Liver8.85
Lung6.7
Lymphnode5.15
Lymphoma_burkitts(Daudi)8
Lymphoma_burkitts(Raji)9.15
MedullaOblongata5.6
OccipitalLobe5.55
OlfactoryBulb4.85
Ovary4.4
Pancreas5.35
PancreaticIslet6.8
ParietalLobe6.95
Pituitary7.3
Placenta6.2
Pons6.05
PrefrontalCortex7.55
Prostate7.45
Salivarygland5.25
SkeletalMuscle8.15
Skin5.45
SmoothMuscle6.95
Spinalcord6.7
SubthalamicNucleus5.9
SuperiorCervicalGanglion9.4
TemporalLobe5.8
Testis5.4
TestisGermCell5.2
TestisIntersitial5.35
TestisLeydigCell6.45
TestisSeminiferousTubule5.25
Thalamus6.65
Thymus4.7
Thyroid8.3
Tongue6.75
Tonsil6.15
Trachea5.2
TrigeminalGanglion7.3
Uterus5
UterusCorpus7
WholeBlood6.6
Wholebrain5.15
colon8.55
pineal_day13.82
pineal_night9.6
retina7.775
small_intestine11.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7524_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.56 ± 0.6
Basal Forebrain5.73 ± 0.25
Basal Part of Pons5.69 ± 0.23
Cerebellar Cortex5.3 ± 0.25
Cerebellar Nuclei6.16 ± 0.35
Claustrum5.27 ± 0.81
Epithalamus6.4 ± 0.27
Frontal Lobe5.79 ± 0.46
Globus Pallidus6.84 ± 0.13
Hypothalamus6.25 ± 0.26
Insula5.73 ± 0.36
Limbic Lobe5.38 ± 0.45
Mesencephalon5.86 ± 0.46
Myelencephalon5.78 ± 0.45
Occipital Lobe5.61 ± 0.44
Parietal Lobe5.77 ± 0.37
Pontine Tegmentum5.93 ± 0.4
Striatum6.21 ± 0.3
Subthalamus5.96 ± 0.18
Temporal Lobe5.72 ± 0.42
Thalamus6.07 ± 0.34
White Matter7.49 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lactb2CBCerebellum16.35
34.71
Lactb2CTXCerebral cortex97.56
92.52
Lactb2HIPHippocampal region39.92
66.53
Lactb2HPFHippocampal formation41.6
58.54
Lactb2HYHypothalamus28.53
28.09
Lactb2LSXLateral septal complex28.24
22.46
Lactb2MBMidbrain27.64
30.94
Lactb2MYMedulla14.83
23.92
Lactb2OLFOlfactory bulb62.17
61.86
Lactb2PPons17.25
26.8
Lactb2PALPallidum43.52
47.77
Lactb2RHPRetrohippocampal region46.02
48.68
Lactb2sAMYStriatum-like amygdalar nuclei37.95
35.4
Lactb2STRStriatum33.03
27.82
Lactb2STRdStriatum dorsal region27.78
23.5
Lactb2STRvStriatum ventral region48.7
36.87
Lactb2THThalamus48.68
47.1
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003926 18 43 60 ILIDTGEPAIPEYISCLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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