AutismKB 2.0

Annotation Detail for SUV420H1


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Basic Information Top
Gene Symbol:SUV420H1 ( CGI85,KMT5B,MGC118906,MGC118909,MGC21161,MGC703 )
Gene Full Name: suppressor of variegation 4-20 homolog 1 (Drosophila)
Band: 11q13.2
Quick LinksEntrez ID:51111; OMIM: 610881; Uniprot ID:SV421_HUMAN; ENSEMBL ID: ENSG00000110066; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus45 / 56401279
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult108 / 193912155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor3 / 3436687
chondrosarcoma6 / 8282372
colorectal tumor4 / 11424635
esophageal tumor2 / 17290115
gastrointestinal tumor9 / 11936975
germ cell tumor20 / 26384575
glioma2 / 10688318
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia11 / 95842114
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma4 / 7175555
non-neoplasia3 / 9725030
normal194 / 336030757
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer3 / 10268029
retinoblastoma5 / 46356107
skin tumor3 / 12494924
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood8 / 12347864
bone7 / 7165597
bone marrow0 / 488010 
brain46 / 110098941
cervix3 / 4817162
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus2 / 2020998
eye14 / 21105466
heart4 / 8962644
intestine8 / 23447234
kidney5 / 21177723
larynx3 / 24145124
liver5 / 20774324
lung19 / 33697456
lymph2 / 4427045
lymph node10 / 91610109
mammary gland6 / 15327139
mouth1 / 6705214
muscle2 / 10771518
nerve1 / 1576863
ovary5 / 10205148
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta23 / 28082581
prostate9 / 18934547
salivary gland2 / 2015599
skin8 / 21057437
spleen3 / 5395255
stomach9 / 9661993
testis23 / 33044269
thymus4 / 8113149
thyroid2 / 4747342
tonsil1 / 1699958
trachea4 / 5241376
umbilical cord0 / 136800 
uterus19 / 23287881
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218242_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts25.85
Adipocyte12.05
AdrenalCortex13.8
Adrenalgland10.45
Amygdala47.3
Appendix15.8
AtrioventricularNode11.55
BDCA4+_DentriticCells129.15
Bonemarrow9.3
BronchialEpithelialCells11
CD105+_Endothelial18.8
CD14+_Monocytes63
CD19+_BCells(neg._sel.)96.2
CD33+_Myeloid62.15
CD34+49.65
CD4+_Tcells100.6
CD56+_NKCells93.95
CD71+_EarlyErythroid21.7
CD8+_Tcells130.3
CardiacMyocytes12.7
Caudatenucleus14.3
Cerebellum19.4
CerebellumPeduncles28.05
CiliaryGanglion8.7
CingulateCortex20.3
Colorectaladenocarcinoma11.75
DorsalRootGanglion7.6
FetalThyroid40.7
Fetalbrain72.75
Fetalliver17.35
Fetallung13.45
GlobusPallidus11.5
Heart13.65
Hypothalamus20.9
Kidney8.95
Leukemia_chronicMyelogenousK-5626.05
Leukemia_promyelocytic-HL-607.3
Leukemialymphoblastic(MOLT-4)9.1
Liver11.25
Lung10.65
Lymphnode15.4
Lymphoma_burkitts(Daudi)14.35
Lymphoma_burkitts(Raji)15.35
MedullaOblongata26.85
OccipitalLobe49.7
OlfactoryBulb22.7
Ovary7
Pancreas12.8
PancreaticIslet20.5
ParietalLobe31.6
Pituitary63.95
Placenta9.2
Pons15.1
PrefrontalCortex149.35
Prostate40.1
Salivarygland12.65
SkeletalMuscle9.25
Skin7.9
SmoothMuscle12.35
Spinalcord11.25
SubthalamicNucleus16.55
SuperiorCervicalGanglion15.3
TemporalLobe12.75
Testis8.1
TestisGermCell25.75
TestisIntersitial14.1
TestisLeydigCell16.6
TestisSeminiferousTubule16.8
Thalamus13.9
Thymus13.45
Thyroid68.5
Tongue10.95
Tonsil37.1
Trachea15.25
TrigeminalGanglion9.65
Uterus100.95
UterusCorpus8.8
WholeBlood25.1
Wholebrain14.05
colon22
pineal_day112.9
pineal_night79.84
retina39.325
small_intestine15.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P96688
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.84 ± 0.31
Basal Forebrain4.89 ± 0.41
Basal Part of Pons4.67 ± 0.38
Cerebellar Cortex5.11 ± 0.26
Cerebellar Nuclei4.3 ± 0.52
Claustrum4.87 ± 0.48
Epithalamus5.22 ± 0.45
Frontal Lobe4.62 ± 0.34
Globus Pallidus4.78 ± 0.5
Hypothalamus4.66 ± 0.39
Insula4.77 ± 0.38
Limbic Lobe4.75 ± 0.4
Mesencephalon4.62 ± 0.54
Myelencephalon4.71 ± 0.44
Occipital Lobe5.01 ± 0.35
Parietal Lobe4.84 ± 0.46
Pontine Tegmentum4.81 ± 0.46
Striatum4.51 ± 0.45
Subthalamus4.51 ± 0.59
Temporal Lobe4.64 ± 0.42
Thalamus4.67 ± 0.37
White Matter5.64 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Suv420h1CBCerebellum18.48
20.39
Suv420h1CTXCerebral cortex37.72
25.9
Suv420h1HIPHippocampal region28.06
34.21
Suv420h1HPFHippocampal formation27.46
27.88
Suv420h1HYHypothalamus16.91
12.2
Suv420h1LSXLateral septal complex26.73
18.13
Suv420h1MBMidbrain14.95
12.58
Suv420h1MYMedulla10.62
10.15
Suv420h1OLFOlfactory bulb33.65
26.46
Suv420h1PPons14.59
13.4
Suv420h1PALPallidum13.18
10.24
Suv420h1RHPRetrohippocampal region26.25
17.93
Suv420h1sAMYStriatum-like amygdalar nuclei14.11
9.87
Suv420h1STRStriatum19.43
13.24
Suv420h1STRdStriatum dorsal region16.88
11.78
Suv420h1STRvStriatum ventral region26.45
16.52
Suv420h1THThalamus19.24
15.24
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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