AutismKB 2.0

Annotation Detail for MRPS2


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Basic Information Top
Gene Symbol:MRPS2 ( MRP-S2,S2mt )
Gene Full Name: mitochondrial ribosomal protein S2
Band: 9q34.3
Quick LinksEntrez ID:51116; OMIM: 611971; Uniprot ID:RT02_HUMAN; ENSEMBL ID: ENSG00000122140; HGNC ID: 14495
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile5 / 5555689
adult130 / 193912167
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor7 / 34366203
chondrosarcoma4 / 8282348
colorectal tumor22 / 114246192
esophageal tumor0 / 172900 
gastrointestinal tumor18 / 119369150
germ cell tumor12 / 26384545
glioma13 / 106883121
head and neck tumor3 / 13630222
kidney tumor5 / 6895972
leukemia12 / 95842125
liver tumor0 / 963590 
lung tumor24 / 103127232
lymphoma15 / 71755209
non-neoplasia3 / 9725030
normal135 / 336030740
ovarian tumor5 / 7668265
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS20 / 125680159
prostate cancer8 / 10268077
retinoblastoma7 / 46356151
skin tumor13 / 124949104
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites6 / 40015149
bladder0 / 297570 
blood10 / 12347880
bone7 / 7165597
bone marrow1 / 4880120
brain38 / 110098934
cervix15 / 48171311
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye16 / 21105475
heart2 / 8962622
intestine31 / 234472132
kidney9 / 21177742
larynx0 / 241450 
liver7 / 20774333
lung37 / 336974109
lymph14 / 44270316
lymph node10 / 91610109
mammary gland10 / 15327165
mouth0 / 670520 
muscle2 / 10771518
nerve2 / 15768126
ovary7 / 10205168
pancreas10 / 21481246
parathyroid6 / 20539292
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta23 / 28082581
prostate10 / 18934552
salivary gland1 / 2015549
skin15 / 21057471
spleen0 / 539520 
stomach4 / 9661941
testis9 / 33044227
thymus0 / 811310 
thyroid2 / 4747342
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord0 / 136800 
uterus18 / 23287877
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218001_at
Cell line Expression level Expression bar
721_B_lymphoblasts162.55
Adipocyte5.1
AdrenalCortex5.15
Adrenalgland10.5
Amygdala5.75
Appendix4.4
AtrioventricularNode3.45
BDCA4+_DentriticCells25.05
Bonemarrow4.4
BronchialEpithelialCells39.85
CD105+_Endothelial57.7
CD14+_Monocytes14.4
CD19+_BCells(neg._sel.)17.75
CD33+_Myeloid13.6
CD34+83.6
CD4+_Tcells12.85
CD56+_NKCells18.3
CD71+_EarlyErythroid4.2
CD8+_Tcells15.45
CardiacMyocytes6.85
Caudatenucleus4
Cerebellum5.45
CerebellumPeduncles5.25
CiliaryGanglion3.15
CingulateCortex4.55
Colorectaladenocarcinoma83.05
DorsalRootGanglion3.4
FetalThyroid4.5
Fetalbrain4.85
Fetalliver3.9
Fetallung4
GlobusPallidus3.3
Heart65.05
Hypothalamus5.05
Kidney4.8
Leukemia_chronicMyelogenousK-56235.25
Leukemia_promyelocytic-HL-6060.4
Leukemialymphoblastic(MOLT-4)16.4
Liver18
Lung19.85
Lymphnode3.8
Lymphoma_burkitts(Daudi)53
Lymphoma_burkitts(Raji)56.6
MedullaOblongata3.95
OccipitalLobe4.35
OlfactoryBulb3.45
Ovary2.8
Pancreas3.55
PancreaticIslet4.85
ParietalLobe4.8
Pituitary5.15
Placenta5.2
Pons4.25
PrefrontalCortex6
Prostate6.55
Salivarygland3.6
SkeletalMuscle5.3
Skin3.45
SmoothMuscle7.05
Spinalcord4.75
SubthalamicNucleus4.15
SuperiorCervicalGanglion5.15
TemporalLobe4.1
Testis3.8
TestisGermCell3.55
TestisIntersitial3.7
TestisLeydigCell4.5
TestisSeminiferousTubule3.7
Thalamus5.6
Thymus3.9
Thyroid9.15
Tongue4.4
Tonsil4.35
Trachea3.7
TrigeminalGanglion4.55
Uterus6.8
UterusCorpus4.1
WholeBlood6.55
Wholebrain12.7
colon7.2
pineal_day5.72
pineal_night5.66
retina13.875
small_intestine8.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5397_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.48 ± 0.94
Basal Forebrain2.92 ± 0.64
Basal Part of Pons3.02 ± 0.64
Cerebellar Cortex3.55 ± 0.82
Cerebellar Nuclei3.31 ± 0.79
Claustrum3.63 ± 0.6
Epithalamus3.21 ± 0.7
Frontal Lobe3.52 ± 0.67
Globus Pallidus2.88 ± 0.58
Hypothalamus3.16 ± 0.53
Insula3.59 ± 0.56
Limbic Lobe3.1 ± 0.78
Mesencephalon3.45 ± 0.65
Myelencephalon3.31 ± 0.71
Occipital Lobe2.8 ± 0.81
Parietal Lobe3.24 ± 0.74
Pontine Tegmentum3.28 ± 0.7
Striatum2.84 ± 0.67
Subthalamus3.36 ± 0.81
Temporal Lobe3.34 ± 0.74
Thalamus3.34 ± 0.65
White Matter2.78 ± 0.72
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mrps2CBCerebellum8.6
9.03
Mrps2CTXCerebral cortex8.74
6.14
Mrps2HIPHippocampal region7.42
6.42
Mrps2HPFHippocampal formation7.61
5.96
Mrps2HYHypothalamus3.11
2.6
Mrps2LSXLateral septal complex0.2
0.15
Mrps2MBMidbrain6.01
6.03
Mrps2MYMedulla16.86
20.84
Mrps2OLFOlfactory bulb13.13
10.42
Mrps2PPons15.19
19.53
Mrps2PALPallidum6.5
6.78
Mrps2RHPRetrohippocampal region8.57
5.7
Mrps2sAMYStriatum-like amygdalar nuclei4.23
2.61
Mrps2STRStriatum3.67
2.85
Mrps2STRdStriatum dorsal region2.86
2.32
Mrps2STRvStriatum ventral region7.64
5.67
Mrps2THThalamus4.62
3.93
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00501318 8 69 76 HSDFFNVK Peptide Atlas
RT02_HUMAN_1 10 1 10 MATSSAALPR PRIDE
RT02_HUMAN_188 22 188 209 LPDLIIFLHTLNNIFEPHVAVR PRIDE
RT02_HUMAN_265 8 265 272 QQVEALYR PRIDE
RT02_HUMAN_42 9 42 50 GSATALMIR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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