AutismKB 2.0

Annotation Detail for ZNF706


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Basic Information Top
Gene Symbol:ZNF706 ( PNAS-106,PNAS-113 )
Gene Full Name: zinc finger protein 706
Band: 8q22.3
Quick LinksEntrez ID:51123; OMIM: NA; Uniprot ID:ZN706_HUMAN; ENSEMBL ID: ENSG00000120963; HGNC ID: 24992
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus41 / 56401272
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult103 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor6 / 26384522
glioma7 / 10688365
head and neck tumor18 / 136302132
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal181 / 336030753
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood8 / 12347864
bone3 / 7165541
bone marrow0 / 488010 
brain66 / 110098959
cervix1 / 4817120
connective tissue2 / 14925513
ear4 / 16212246
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye7 / 21105433
heart6 / 8962666
intestine8 / 23447234
kidney10 / 21177747
larynx1 / 2414541
liver5 / 20774324
lung18 / 33697453
lymph1 / 4427022
lymph node3 / 9161032
mammary gland5 / 15327132
mouth4 / 6705259
muscle3 / 10771527
nerve1 / 1576863
ovary2 / 10205119
pancreas14 / 21481265
parathyroid1 / 2053948
pharynx16 / 41328387
pituitary gland0 / 165850 
placenta25 / 28082589
prostate7 / 18934536
salivary gland1 / 2015549
skin6 / 21057428
spleen0 / 539520 
stomach4 / 9661941
testis9 / 33044227
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus7 / 23287830
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218059_at
Cell line Expression level Expression bar
721_B_lymphoblasts1192
Adipocyte180.95
AdrenalCortex48
Adrenalgland158.05
Amygdala291.95
Appendix50.2
AtrioventricularNode35.2
BDCA4+_DentriticCells1238.3
Bonemarrow175.85
BronchialEpithelialCells342.05
CD105+_Endothelial541.65
CD14+_Monocytes678
CD19+_BCells(neg._sel.)907.75
CD33+_Myeloid669.5
CD34+893.4
CD4+_Tcells591.15
CD56+_NKCells699.4
CD71+_EarlyErythroid154.9
CD8+_Tcells493.25
CardiacMyocytes266.3
Caudatenucleus155.9
Cerebellum127.2
CerebellumPeduncles158.1
CiliaryGanglion54.45
CingulateCortex108.8
Colorectaladenocarcinoma378.65
DorsalRootGanglion92.25
FetalThyroid229.2
Fetalbrain221.95
Fetalliver103.75
Fetallung165.95
GlobusPallidus70.85
Heart251.75
Hypothalamus235
Kidney95.25
Leukemia_chronicMyelogenousK-562228.15
Leukemia_promyelocytic-HL-60306.75
Leukemialymphoblastic(MOLT-4)401.7
Liver185.9
Lung499.9
Lymphnode241
Lymphoma_burkitts(Daudi)605.2
Lymphoma_burkitts(Raji)566.35
MedullaOblongata112.25
OccipitalLobe161.45
OlfactoryBulb397.35
Ovary73.4
Pancreas232
PancreaticIslet429.3
ParietalLobe88.6
Pituitary248.05
Placenta331.9
Pons45.75
PrefrontalCortex229.15
Prostate385.65
Salivarygland138.7
SkeletalMuscle39.5
Skin99.2
SmoothMuscle201.05
Spinalcord311.45
SubthalamicNucleus99.5
SuperiorCervicalGanglion35.35
TemporalLobe55.05
Testis237.15
TestisGermCell202.65
TestisIntersitial279.5
TestisLeydigCell138.6
TestisSeminiferousTubule195.85
Thalamus153.95
Thymus295.65
Thyroid448.35
Tongue215.2
Tonsil372.1
Trachea171.4
TrigeminalGanglion27.1
Uterus189.85
UterusCorpus99.9
WholeBlood311.85
Wholebrain306.3
colon264.15
pineal_day250.62
pineal_night250.52
retina276
small_intestine241.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P252704
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.66 ± 0.17
Basal Forebrain10.44 ± 0.14
Basal Part of Pons10.28 ± 0.16
Cerebellar Cortex10.64 ± 0.18
Cerebellar Nuclei10.58 ± 0.13
Claustrum10.32 ± 0.19
Epithalamus10.58 ± 0.14
Frontal Lobe10.51 ± 0.21
Globus Pallidus10.77 ± 0.13
Hypothalamus10.29 ± 0.19
Insula10.67 ± 0.21
Limbic Lobe10.66 ± 0.25
Mesencephalon10.46 ± 0.23
Myelencephalon10.51 ± 0.21
Occipital Lobe10.4 ± 0.19
Parietal Lobe10.45 ± 0.2
Pontine Tegmentum10.57 ± 0.18
Striatum10.5 ± 0.16
Subthalamus10.3 ± 0.16
Temporal Lobe10.62 ± 0.24
Thalamus10.38 ± 0.15
White Matter11.09 ± 0.07
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp706CBCerebellum26.25
51.73
Zfp706CTXCerebral cortex82.66
73.08
Zfp706HIPHippocampal region70.87
100
Zfp706HPFHippocampal formation76.97
100
Zfp706HYHypothalamus25.48
23.13
Zfp706LSXLateral septal complex38.43
36.2
Zfp706MBMidbrain40.56
41.37
Zfp706MYMedulla39.21
47.16
Zfp706OLFOlfactory bulb57.53
54.42
Zfp706PPons35.51
43.08
Zfp706PALPallidum38.62
41.09
Zfp706RHPRetrohippocampal region87.86
88.12
Zfp706sAMYStriatum-like amygdalar nuclei61.84
54.74
Zfp706STRStriatum68.09
58.75
Zfp706STRdStriatum dorsal region70.83
61
Zfp706STRvStriatum ventral region73.79
61.64
Zfp706THThalamus59.21
66.02
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009150 11 35 45 AALIYTCTVCR Peptide Atlas
ZN706_HUMAN_34 11 34 44 AALIYTCTVCR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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