AutismKB 2.0

Annotation Detail for IER3IP1


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Basic Information Top
Gene Symbol:IER3IP1 ( PRO2309 )
Gene Full Name: immediate early response 3 interacting protein 1
Band: 18q21.1
Quick LinksEntrez ID:51124; OMIM: 609382; Uniprot ID:IR3IP_HUMAN; ENSEMBL ID: ENSG00000134049; HGNC ID: 18550
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus11 / 56401219
neonate1 / 3109732
infant1 / 2362042
juvenile2 / 5555635
adult58 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma5 / 17475286
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor5 / 26384518
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor9 / 68959130
leukemia12 / 95842125
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal149 / 336030744
ovarian tumor3 / 7668239
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma4 / 4635686
skin tumor8 / 12494964
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites1 / 4001524
bladder6 / 29757201
blood2 / 12347816
bone3 / 7165541
bone marrow13 / 48801266
brain50 / 110098945
cervix2 / 4817141
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye12 / 21105456
heart2 / 8962622
intestine5 / 23447221
kidney22 / 211777103
larynx0 / 241450 
liver5 / 20774324
lung13 / 33697438
lymph0 / 442700 
lymph node4 / 9161043
mammary gland5 / 15327132
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary3 / 10205129
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland2 / 16585120
placenta17 / 28082560
prostate3 / 18934515
salivary gland8 / 20155396
skin12 / 21057456
spleen1 / 5395218
stomach3 / 9661931
testis15 / 33044245
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus12 / 23287851
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P429872
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.23 ± 0.54
Basal Forebrain4.99 ± 0.23
Basal Part of Pons5.85 ± 0.39
Cerebellar Cortex5.8 ± 0.22
Cerebellar Nuclei5.99 ± 0.35
Claustrum5.38 ± 0.29
Epithalamus5.48 ± 0.46
Frontal Lobe5.58 ± 0.39
Globus Pallidus5.59 ± 0.29
Hypothalamus5.75 ± 0.49
Insula5.45 ± 0.38
Limbic Lobe5.22 ± 0.53
Mesencephalon5.46 ± 0.43
Myelencephalon5.41 ± 0.47
Occipital Lobe5.29 ± 0.47
Parietal Lobe5.51 ± 0.45
Pontine Tegmentum5.43 ± 0.41
Striatum4.96 ± 0.37
Subthalamus5.84 ± 0.34
Temporal Lobe5.42 ± 0.38
Thalamus5.5 ± 0.39
White Matter5.75 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ier3ip1CBCerebellum7.34
14.04
Ier3ip1CTXCerebral cortex4.16
3.26
Ier3ip1HIPHippocampal region14.25
16.39
Ier3ip1HPFHippocampal formation9.59
10.09
Ier3ip1HYHypothalamus1.24
1.13
Ier3ip1LSXLateral septal complex0.51
0.81
Ier3ip1MBMidbrain2.9
3.54
Ier3ip1MYMedulla2.78
4.46
Ier3ip1OLFOlfactory bulb1.79
2.57
Ier3ip1PPons2.75
3.76
Ier3ip1PALPallidum0.82
1.29
Ier3ip1RHPRetrohippocampal region1.31
1.09
Ier3ip1sAMYStriatum-like amygdalar nuclei0.43
0.4
Ier3ip1STRStriatum0.37
0.53
Ier3ip1STRdStriatum dorsal region0.38
0.55
Ier3ip1STRvStriatum ventral region0.3
0.53
Ier3ip1THThalamus1.58
1.75
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00075346 20 30 49 NIGWGTDQGIGGFGEEPGIK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018