AutismKB 2.0

Annotation Detail for SAR1B


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Basic Information Top
Gene Symbol:SAR1B ( ANDD,CMRD,GTBPB,SARA2 )
Gene Full Name: SAR1 homolog B (S. cerevisiae)
Band: 5q31.1
Quick LinksEntrez ID:51128; OMIM: 607690; Uniprot ID:SAR1B_HUMAN; ENSEMBL ID: ENSG00000152700; HGNC ID: 10535
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus49 / 56401286
neonate4 / 31097128
infant1 / 2362042
juvenile8 / 55556143
adult165 / 193912185
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor5 / 34366145
chondrosarcoma5 / 8282360
colorectal tumor12 / 114246105
esophageal tumor1 / 1729057
gastrointestinal tumor11 / 11936992
germ cell tumor6 / 26384522
glioma7 / 10688365
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor13 / 96359134
lung tumor4 / 10312738
lymphoma7 / 7175597
non-neoplasia10 / 97250102
normal278 / 336030782
ovarian tumor4 / 7668252
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer12 / 102680116
retinoblastoma0 / 463560 
skin tumor11 / 12494988
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland7 / 33197210
ascites6 / 40015149
bladder3 / 29757100
blood5 / 12347840
bone6 / 7165583
bone marrow6 / 48801122
brain86 / 110098978
cervix5 / 48171103
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye5 / 21105423
heart13 / 89626145
intestine24 / 234472102
kidney18 / 21177784
larynx3 / 24145124
liver25 / 207743120
lung24 / 33697471
lymph1 / 4427022
lymph node11 / 91610120
mammary gland7 / 15327145
mouth1 / 6705214
muscle22 / 107715204
nerve2 / 15768126
ovary7 / 10205168
pancreas17 / 21481279
parathyroid4 / 20539194
pharynx25 / 41328604
pituitary gland2 / 16585120
placenta12 / 28082542
prostate21 / 189345110
salivary gland0 / 201550 
skin15 / 21057471
spleen0 / 539520 
stomach6 / 9661962
testis14 / 33044242
thymus3 / 8113136
thyroid3 / 4747363
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord3 / 13680219
uterus11 / 23287847
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218254_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts88.05
Adipocyte44.05
AdrenalCortex22.85
Adrenalgland46
Amygdala38.5
Appendix21.4
AtrioventricularNode17.6
BDCA4+_DentriticCells30.95
Bonemarrow18.95
BronchialEpithelialCells90.6
CD105+_Endothelial57.6
CD14+_Monocytes27.15
CD19+_BCells(neg._sel.)19.7
CD33+_Myeloid24.05
CD34+21.8
CD4+_Tcells17.25
CD56+_NKCells25.15
CD71+_EarlyErythroid26.2
CD8+_Tcells13.95
CardiacMyocytes30.9
Caudatenucleus27.95
Cerebellum16.2
CerebellumPeduncles18.9
CiliaryGanglion15.45
CingulateCortex19.85
Colorectaladenocarcinoma23.95
DorsalRootGanglion16.9
FetalThyroid24.6
Fetalbrain19.3
Fetalliver48.3
Fetallung17.2
GlobusPallidus12.55
Heart29.3
Hypothalamus33.2
Kidney28.9
Leukemia_chronicMyelogenousK-56250.05
Leukemia_promyelocytic-HL-6052.75
Leukemialymphoblastic(MOLT-4)18.25
Liver58.6
Lung21
Lymphnode20.6
Lymphoma_burkitts(Daudi)28.25
Lymphoma_burkitts(Raji)28.45
MedullaOblongata17.5
OccipitalLobe19.15
OlfactoryBulb15.15
Ovary12.2
Pancreas16.05
PancreaticIslet57.9
ParietalLobe21.5
Pituitary38.4
Placenta35.1
Pons19
PrefrontalCortex23.3
Prostate115.6
Salivarygland20.65
SkeletalMuscle32.6
Skin17.05
SmoothMuscle46.85
Spinalcord74.5
SubthalamicNucleus19.75
SuperiorCervicalGanglion30.9
TemporalLobe13.45
Testis33.65
TestisGermCell18.15
TestisIntersitial29.75
TestisLeydigCell22.65
TestisSeminiferousTubule18.7
Thalamus22.65
Thymus20.65
Thyroid72.95
Tongue24.6
Tonsil18.9
Trachea36
TrigeminalGanglion21.5
Uterus21.25
UterusCorpus14.75
WholeBlood40.2
Wholebrain24.25
colon155
pineal_day108.74
pineal_night116.62
retina41.6
small_intestine457
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13726_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.34 ± 0.13
Basal Forebrain6.5 ± 0.36
Basal Part of Pons6.41 ± 0.17
Cerebellar Cortex6.42 ± 0.3
Cerebellar Nuclei6.97 ± 0.4
Claustrum6.31 ± 0.39
Epithalamus6.46 ± 0.38
Frontal Lobe6.41 ± 0.36
Globus Pallidus7.39 ± 0.25
Hypothalamus6.41 ± 0.42
Insula6.36 ± 0.24
Limbic Lobe6.51 ± 0.36
Mesencephalon6.59 ± 0.34
Myelencephalon6.54 ± 0.42
Occipital Lobe6.79 ± 0.39
Parietal Lobe6.52 ± 0.34
Pontine Tegmentum6.59 ± 0.5
Striatum6.71 ± 0.38
Subthalamus6.5 ± 0.1
Temporal Lobe6.37 ± 0.31
Thalamus6.58 ± 0.34
White Matter7.79 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sar1bCBCerebellum42.64
99.73
Sar1bCTXCerebral cortex100
100
Sar1bHIPHippocampal region99.1
100
Sar1bHPFHippocampal formation100
100
Sar1bHYHypothalamus100
99.45
Sar1bLSXLateral septal complex100
100
Sar1bMBMidbrain98.08
100
Sar1bMYMedulla98.54
100
Sar1bOLFOlfactory bulb100
100
Sar1bPPons88.97
100
Sar1bPALPallidum96.84
100
Sar1bRHPRetrohippocampal region100
100
Sar1bsAMYStriatum-like amygdalar nuclei100
92.98
Sar1bSTRStriatum100
100
Sar1bSTRdStriatum dorsal region100
100
Sar1bSTRvStriatum ventral region100
100
Sar1bTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024964 16 167 182 ELNARPLEVFMCSVLK Peptide Atlas
SAR1B_HUMAN_0 0 0 0 IDRPEAISEER PRIDE
SAR1B_HUMAN_0 0 0 0 LVFLGLDNAGK PRIDE
SAR1B_HUMAN_135 11 135 145 IDRPEAISEER PRIDE
SAR1B_HUMAN_136 11 136 146 IDRPEAISEER PRIDE
SAR1B_HUMAN_149 12 149 160 EMFGLYGQTTGK PRIDE
SAR1B_HUMAN_166 16 166 181 ELNARPLEVFMCSVLK PRIDE
SAR1B_HUMAN_166 17 166 182 ELNARPLEVFMCSVLKR PRIDE
SAR1B_HUMAN_27 11 27 37 LVFLGLDNAGK PRIDE
SAR1B_HUMAN_38 11 38 48 TTLLHMLKDDR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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