AutismKB 2.0

Annotation Detail for ANGPTL4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ANGPTL4 ( ANGPTL2,ARP4,FIAF,HFARP,NL2,PGAR,pp1158 )
Gene Full Name: angiopoietin-like 4
Band: 19p13.2
Quick LinksEntrez ID:51129; OMIM: 605910; Uniprot ID:ANGL4_HUMAN; ENSEMBL ID: ENSG00000167772; HGNC ID: 16039
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus8 / 56401214
neonate0 / 310970 
infant1 / 2362042
juvenile5 / 5555689
adult105 / 193912154
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma15 / 106883140
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor9 / 9635993
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia9 / 9725092
normal163 / 336030748
ovarian tumor2 / 7668226
pancreatic tumor18 / 104616172
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone6 / 7165583
bone marrow1 / 4880120
brain39 / 110098935
cervix0 / 481710 
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye7 / 21105433
heart5 / 8962655
intestine10 / 23447242
kidney7 / 21177733
larynx0 / 241450 
liver15 / 20774372
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve3 / 15768190
ovary2 / 10205119
pancreas24 / 214812111
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta52 / 280825185
prostate8 / 18934542
salivary gland0 / 201550 
skin20 / 21057494
spleen1 / 5395218
stomach1 / 9661910
testis6 / 33044218
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221009_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.5
Adipocyte14.55
AdrenalCortex19.45
Adrenalgland5.25
Amygdala5.9
Appendix8.05
AtrioventricularNode6.25
BDCA4+_DentriticCells6
Bonemarrow6.2
BronchialEpithelialCells25.8
CD105+_Endothelial6
CD14+_Monocytes6.15
CD19+_BCells(neg._sel.)6.95
CD33+_Myeloid7.25
CD34+7.95
CD4+_Tcells6.05
CD56+_NKCells6.7
CD71+_EarlyErythroid5.7
CD8+_Tcells5.4
CardiacMyocytes11.3
Caudatenucleus6
Cerebellum4.8
CerebellumPeduncles8.1
CiliaryGanglion13.85
CingulateCortex12.05
Colorectaladenocarcinoma5.8
DorsalRootGanglion13
FetalThyroid8.2
Fetalbrain5.85
Fetalliver5.05
Fetallung4.45
GlobusPallidus7
Heart8.4
Hypothalamus7.9
Kidney5.15
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-605.15
Leukemialymphoblastic(MOLT-4)4.7
Liver61.05
Lung6.55
Lymphnode4.85
Lymphoma_burkitts(Daudi)7.7
Lymphoma_burkitts(Raji)8.2
MedullaOblongata5.55
OccipitalLobe5.4
OlfactoryBulb5.45
Ovary4.5
Pancreas10.15
PancreaticIslet32
ParietalLobe7.4
Pituitary7.65
Placenta17.35
Pons12
PrefrontalCortex7.2
Prostate8.45
Salivarygland4.9
SkeletalMuscle9.15
Skin5.05
SmoothMuscle6.75
Spinalcord14.05
SubthalamicNucleus15.15
SuperiorCervicalGanglion7.65
TemporalLobe22.9
Testis5.15
TestisGermCell4.75
TestisIntersitial5.05
TestisLeydigCell5.95
TestisSeminiferousTubule5.1
Thalamus9.4
Thymus4.4
Thyroid7.35
Tongue7.35
Tonsil5.75
Trachea4.9
TrigeminalGanglion7.8
Uterus4.7
UterusCorpus6.45
WholeBlood6.25
Wholebrain4.65
colon5.65
pineal_day7.3
pineal_night7.04
retina7.85
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P170719
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.64 ± 0.38
Basal Forebrain6.87 ± 0.32
Basal Part of Pons5.86 ± 0.44
Cerebellar Cortex5.9 ± 0.33
Cerebellar Nuclei6.57 ± 0.62
Claustrum5.38 ± 0.63
Epithalamus6.61 ± 0.47
Frontal Lobe6.43 ± 0.63
Globus Pallidus8.6 ± 0.57
Hypothalamus6.75 ± 0.35
Insula6.31 ± 0.44
Limbic Lobe6.2 ± 0.73
Mesencephalon6.93 ± 0.59
Myelencephalon6.65 ± 0.75
Occipital Lobe6.48 ± 0.51
Parietal Lobe6.64 ± 0.65
Pontine Tegmentum6.84 ± 0.46
Striatum7.32 ± 0.44
Subthalamus6.52 ± 0.48
Temporal Lobe6.61 ± 0.52
Thalamus7.22 ± 0.4
White Matter7.72 ± 0.61
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Angptl4CBCerebellum1.52
1.99
Angptl4CTXCerebral cortex0.93
1.24
Angptl4HIPHippocampal region0.49
0.59
Angptl4HPFHippocampal formation0.41
0.47
Angptl4HYHypothalamus0.14
0.11
Angptl4LSXLateral septal complex0.64
1.19
Angptl4MBMidbrain0.44
0.64
Angptl4MYMedulla1.31
1.47
Angptl4OLFOlfactory bulb3.77
4.76
Angptl4PPons0.68
0.94
Angptl4PALPallidum0.1
0.09
Angptl4RHPRetrohippocampal region0.22
0.27
Angptl4sAMYStriatum-like amygdalar nuclei0.36
0.34
Angptl4STRStriatum0.33
0.36
Angptl4STRdStriatum dorsal region0.24
0.32
Angptl4STRvStriatum ventral region0.42
0.25
Angptl4THThalamus0.36
0.33
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00967960 11 187 197 DCQELFQVGER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved