AutismKB 2.0

Annotation Detail for KCTD3


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Basic Information Top
Gene Symbol:KCTD3 ( MGC43935,NY-REN-45 )
Gene Full Name: potassium channel tetramerisation domain containing 3
Band: 1q41
Quick LinksEntrez ID:51133; OMIM: 613272; Uniprot ID:KCTD3_HUMAN; ENSEMBL ID: ENSG00000136636; HGNC ID: 21305
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst7 / 62319112
fetus37 / 56401265
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult98 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma5 / 17475286
breast (mammary gland) tumor9 / 9417895
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor11 / 26384541
glioma11 / 106883102
head and neck tumor12 / 13630288
kidney tumor4 / 6895958
leukemia7 / 9584273
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal175 / 336030752
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer5 / 10268048
retinoblastoma4 / 4635686
skin tumor9 / 12494972
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder6 / 29757201
blood4 / 12347832
bone1 / 7165513
bone marrow4 / 4880181
brain50 / 110098945
cervix2 / 4817141
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye8 / 21105437
heart8 / 8962689
intestine14 / 23447259
kidney16 / 21177775
larynx5 / 24145207
liver9 / 20774343
lung15 / 33697444
lymph0 / 442700 
lymph node4 / 9161043
mammary gland19 / 153271123
mouth2 / 6705229
muscle4 / 10771537
nerve2 / 15768126
ovary2 / 10205119
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta13 / 28082546
prostate9 / 18934547
salivary gland0 / 201550 
skin14 / 21057466
spleen0 / 539520 
stomach7 / 9661972
testis15 / 33044245
thymus1 / 8113112
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217894_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.8
Adipocyte13.1
AdrenalCortex26.7
Adrenalgland15
Amygdala46.75
Appendix22.6
AtrioventricularNode23.6
BDCA4+_DentriticCells13.1
Bonemarrow15.85
BronchialEpithelialCells18
CD105+_Endothelial26.9
CD14+_Monocytes16.2
CD19+_BCells(neg._sel.)15.15
CD33+_Myeloid20.85
CD34+30.4
CD4+_Tcells11.25
CD56+_NKCells12.6
CD71+_EarlyErythroid14.45
CD8+_Tcells8.45
CardiacMyocytes26.2
Caudatenucleus13.6
Cerebellum11.8
CerebellumPeduncles19.4
CiliaryGanglion19.45
CingulateCortex15.15
Colorectaladenocarcinoma15.05
DorsalRootGanglion15.6
FetalThyroid16.3
Fetalbrain21.4
Fetalliver13.3
Fetallung15.3
GlobusPallidus11.25
Heart22.3
Hypothalamus18.95
Kidney13.4
Leukemia_chronicMyelogenousK-56214.05
Leukemia_promyelocytic-HL-6011.15
Leukemialymphoblastic(MOLT-4)8.8
Liver22.2
Lung13
Lymphnode12.65
Lymphoma_burkitts(Daudi)18.35
Lymphoma_burkitts(Raji)20.55
MedullaOblongata13.15
OccipitalLobe14.55
OlfactoryBulb10.7
Ovary12.55
Pancreas13.45
PancreaticIslet15.6
ParietalLobe16.45
Pituitary17.65
Placenta15.65
Pons14.25
PrefrontalCortex16.25
Prostate25.1
Salivarygland12.5
SkeletalMuscle28.25
Skin18.95
SmoothMuscle15.45
Spinalcord34
SubthalamicNucleus13.35
SuperiorCervicalGanglion33
TemporalLobe13.8
Testis10.85
TestisGermCell16.15
TestisIntersitial12.45
TestisLeydigCell16.7
TestisSeminiferousTubule11.25
Thalamus15.65
Thymus8.8
Thyroid42.55
Tongue22.65
Tonsil14.35
Trachea11.5
TrigeminalGanglion25.15
Uterus44.95
UterusCorpus19.4
WholeBlood12.1
Wholebrain10.8
colon105.5
pineal_day17.96
pineal_night17.62
retina19.025
small_intestine93.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1906_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.09 ± 0.22
Basal Forebrain7.32 ± 0.1
Basal Part of Pons7.05 ± 0.21
Cerebellar Cortex7.47 ± 0.2
Cerebellar Nuclei7.18 ± 0.4
Claustrum6.78 ± 0.38
Epithalamus7.42 ± 0.28
Frontal Lobe7.04 ± 0.33
Globus Pallidus7.8 ± 0.43
Hypothalamus7.25 ± 0.25
Insula6.96 ± 0.39
Limbic Lobe7.17 ± 0.4
Mesencephalon7.25 ± 0.44
Myelencephalon7.15 ± 0.38
Occipital Lobe7.55 ± 0.41
Parietal Lobe7.15 ± 0.31
Pontine Tegmentum7.24 ± 0.34
Striatum7.38 ± 0.5
Subthalamus7.16 ± 0.12
Temporal Lobe7.1 ± 0.25
Thalamus7.28 ± 0.3
White Matter8.44 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Kctd3CBCerebellum77.44
100
Kctd3CTXCerebral cortex100
100
Kctd3HIPHippocampal region92.29
100
Kctd3HPFHippocampal formation92.14
100
Kctd3HYHypothalamus54.6
44.52
Kctd3LSXLateral septal complex50.81
38.45
Kctd3MBMidbrain89.33
81.48
Kctd3MYMedulla100
99.62
Kctd3OLFOlfactory bulb84.55
80.1
Kctd3PPons95.02
87.43
Kctd3PALPallidum51.47
46.35
Kctd3RHPRetrohippocampal region91.6
81.58
Kctd3sAMYStriatum-like amygdalar nuclei61.42
49.27
Kctd3STRStriatum67.16
52.87
Kctd3STRdStriatum dorsal region71.67
57.62
Kctd3STRvStriatum ventral region51.84
37.76
Kctd3THThalamus100
93.34
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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