AutismKB 2.0

Annotation Detail for PCNT


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Basic Information Top
Gene Symbol:PCNT ( KEN,MOPD2,PCN,PCNT2,PCNTB,PCTN2,SCKL4 )
Gene Full Name: pericentrin
Band: 21q22.3
Quick LinksEntrez ID:5116; OMIM: 605925; Uniprot ID:PCNT_HUMAN; ENSEMBL ID: ENSG00000160299; HGNC ID: 16068
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus36 / 56401263
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor12 / 26384545
glioma5 / 10688346
head and neck tumor8 / 13630258
kidney tumor1 / 6895914
leukemia8 / 9584283
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal116 / 336030734
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma8 / 46356172
skin tumor3 / 12494924
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder1 / 2975733
blood7 / 12347856
bone0 / 716550 
bone marrow0 / 488010 
brain34 / 110098930
cervix2 / 4817141
connective tissue12 / 14925580
ear1 / 1621261
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye14 / 21105466
heart4 / 8962644
intestine9 / 23447238
kidney1 / 2117774
larynx3 / 24145124
liver12 / 20774357
lung8 / 33697423
lymph0 / 442700 
lymph node9 / 9161098
mammary gland7 / 15327145
mouth3 / 6705244
muscle4 / 10771537
nerve1 / 1576863
ovary3 / 10205129
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta10 / 28082535
prostate4 / 18934521
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach3 / 9661931
testis14 / 33044242
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203660_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts25.8
Adipocyte6.8
AdrenalCortex6.95
Adrenalgland5.85
Amygdala8.25
Appendix6.8
AtrioventricularNode5.1
BDCA4+_DentriticCells105.2
Bonemarrow8.1
BronchialEpithelialCells6.5
CD105+_Endothelial7.95
CD14+_Monocytes7.5
CD19+_BCells(neg._sel.)7.5
CD33+_Myeloid9.75
CD34+13
CD4+_Tcells41.85
CD56+_NKCells70.35
CD71+_EarlyErythroid134.4
CD8+_Tcells142.8
CardiacMyocytes8.55
Caudatenucleus15.7
Cerebellum5.65
CerebellumPeduncles7.75
CiliaryGanglion4.75
CingulateCortex8.6
Colorectaladenocarcinoma8.6
DorsalRootGanglion5.15
FetalThyroid7.95
Fetalbrain9
Fetalliver7.45
Fetallung5.85
GlobusPallidus5.4
Heart8.8
Hypothalamus9.65
Kidney5.5
Leukemia_chronicMyelogenousK-56218.75
Leukemia_promyelocytic-HL-609.8
Leukemialymphoblastic(MOLT-4)68.45
Liver9
Lung7.1
Lymphnode6.9
Lymphoma_burkitts(Daudi)14.35
Lymphoma_burkitts(Raji)9.55
MedullaOblongata11.1
OccipitalLobe8.8
OlfactoryBulb5.15
Ovary4.5
Pancreas5.35
PancreaticIslet7.35
ParietalLobe7.3
Pituitary12.15
Placenta7.25
Pons9.9
PrefrontalCortex12.55
Prostate8.15
Salivarygland5.45
SkeletalMuscle531.15
Skin5.15
SmoothMuscle7.15
Spinalcord7.45
SubthalamicNucleus6.25
SuperiorCervicalGanglion7.6
TemporalLobe6.3
Testis13.8
TestisGermCell13.1
TestisIntersitial6.9
TestisLeydigCell8.7
TestisSeminiferousTubule9.15
Thalamus7.1
Thymus7.85
Thyroid8.85
Tongue9.6
Tonsil6.8
Trachea5.8
TrigeminalGanglion6.65
Uterus5.75
UterusCorpus6.1
WholeBlood7.1
Wholebrain8.3
colon6.9
pineal_day6.5
pineal_night7.34
retina8.75
small_intestine6.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P8350
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.19 ± 0.37
Basal Forebrain8.19 ± 0.19
Basal Part of Pons8.26 ± 0.37
Cerebellar Cortex7.54 ± 0.17
Cerebellar Nuclei7.67 ± 0.4
Claustrum8.5 ± 0.46
Epithalamus7.34 ± 0.31
Frontal Lobe7.68 ± 0.34
Globus Pallidus7.96 ± 0.27
Hypothalamus7.47 ± 0.34
Insula7.79 ± 0.34
Limbic Lobe8 ± 0.46
Mesencephalon7.8 ± 0.4
Myelencephalon7.89 ± 0.5
Occipital Lobe8.48 ± 0.5
Parietal Lobe8 ± 0.35
Pontine Tegmentum7.75 ± 0.39
Striatum8.85 ± 0.31
Subthalamus7.87 ± 0.24
Temporal Lobe7.75 ± 0.4
Thalamus7.77 ± 0.31
White Matter8.09 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PcntCBCerebellum19.57
16.05
PcntCTXCerebral cortex6.83
4.81
PcntHIPHippocampal region7.86
4.44
PcntHPFHippocampal formation11.74
8.66
PcntHYHypothalamus2.66
1.49
PcntLSXLateral septal complex1.85
1.22
PcntMBMidbrain3.23
2.41
PcntMYMedulla8.38
6.36
PcntOLFOlfactory bulb10.47
5.85
PcntPPons10.98
8.82
PcntPALPallidum2.07
1.43
PcntRHPRetrohippocampal region17.95
13.8
PcntsAMYStriatum-like amygdalar nuclei1.85
1.05
PcntSTRStriatum2.06
1.24
PcntSTRdStriatum dorsal region1.23
0.85
PcntSTRvStriatum ventral region4.25
2.11
PcntTHThalamus2.15
1.22
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00501257 24 2401 2424 DESHQILALSEGLAPPSGEPHPPR Peptide Atlas
PCNT_HUMAN_1493 9 1493 1501 EEFQQEIQR PRIDE
PCNT_HUMAN_1696 10 1696 1705 ELEEENTSLK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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