AutismKB 2.0

Annotation Detail for EGFL7


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Basic Information Top
Gene Symbol:EGFL7 ( MGC111117,RP11-251M1.2,VE-STATIN,ZNEU1 )
Gene Full Name: EGF-like-domain, multiple 7
Band: 9q34.3
Quick LinksEntrez ID:51162; OMIM: 608582; Uniprot ID:EGFL7_HUMAN; ENSEMBL ID: ENSG00000172889; HGNC ID: 20594
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult121 / 193912162
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor14 / 26384553
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal176 / 336030752
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer6 / 10268058
retinoblastoma3 / 4635664
skin tumor10 / 12494980
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain24 / 110098921
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye11 / 21105452
heart6 / 8962666
intestine3 / 23447212
kidney17 / 21177780
larynx0 / 241450 
liver2 / 2077439
lung20 / 33697459
lymph0 / 442700 
lymph node0 / 916100 
mammary gland8 / 15327152
mouth2 / 6705229
muscle1 / 1077159
nerve1 / 1576863
ovary4 / 10205139
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta49 / 280825174
prostate9 / 18934547
salivary gland1 / 2015549
skin11 / 21057452
spleen2 / 5395237
stomach3 / 9661931
testis4 / 33044212
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218825_at
Cell line Expression level Expression bar
721_B_lymphoblasts22.55
Adipocyte23.55
AdrenalCortex47.95
Adrenalgland33.25
Amygdala28.15
Appendix42.2
AtrioventricularNode25.4
BDCA4+_DentriticCells15.9
Bonemarrow25.65
BronchialEpithelialCells24.35
CD105+_Endothelial89.25
CD14+_Monocytes21.65
CD19+_BCells(neg._sel.)25.35
CD33+_Myeloid26.55
CD34+298.95
CD4+_Tcells15.85
CD56+_NKCells24.15
CD71+_EarlyErythroid23.7
CD8+_Tcells15.1
CardiacMyocytes111.55
Caudatenucleus32
Cerebellum25.55
CerebellumPeduncles35
CiliaryGanglion13.25
CingulateCortex85.35
Colorectaladenocarcinoma29.1
DorsalRootGanglion19.45
FetalThyroid108.15
Fetalbrain22.7
Fetalliver23.4
Fetallung183.65
GlobusPallidus43.25
Heart106.75
Hypothalamus49.9
Kidney44.3
Leukemia_chronicMyelogenousK-56295.05
Leukemia_promyelocytic-HL-6016.55
Leukemialymphoblastic(MOLT-4)16.8
Liver49.7
Lung156.95
Lymphnode58.85
Lymphoma_burkitts(Daudi)20.7
Lymphoma_burkitts(Raji)24
MedullaOblongata31.3
OccipitalLobe37.85
OlfactoryBulb26.05
Ovary20.75
Pancreas21
PancreaticIslet33.65
ParietalLobe49.15
Pituitary47.6
Placenta133.15
Pons46.75
PrefrontalCortex75.95
Prostate31.35
Salivarygland22.2
SkeletalMuscle44.95
Skin19.3
SmoothMuscle79.3
Spinalcord35.25
SubthalamicNucleus57.45
SuperiorCervicalGanglion17.85
TemporalLobe57.2
Testis66.9
TestisGermCell40.75
TestisIntersitial21.95
TestisLeydigCell34.35
TestisSeminiferousTubule35
Thalamus56.25
Thymus20.4
Thyroid47.55
Tongue26.1
Tonsil20.05
Trachea23.95
TrigeminalGanglion28.2
Uterus31.75
UterusCorpus25.25
WholeBlood15.9
Wholebrain34.8
colon14.3
pineal_day21.62
pineal_night21.68
retina43.025
small_intestine12.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11794_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.92 ± 0.61
Basal Forebrain5.93 ± 0.76
Basal Part of Pons6.48 ± 0.55
Cerebellar Cortex5.68 ± 0.32
Cerebellar Nuclei6.41 ± 0.57
Claustrum5.89 ± 0.89
Epithalamus5.95 ± 0.77
Frontal Lobe6.67 ± 0.54
Globus Pallidus5.83 ± 0.81
Hypothalamus6.46 ± 0.53
Insula6.51 ± 0.35
Limbic Lobe6.13 ± 0.69
Mesencephalon6.12 ± 0.63
Myelencephalon6.4 ± 0.57
Occipital Lobe5.76 ± 0.63
Parietal Lobe6.48 ± 0.58
Pontine Tegmentum6.33 ± 0.73
Striatum5.83 ± 0.83
Subthalamus6.7 ± 0.2
Temporal Lobe6.51 ± 0.46
Thalamus6.28 ± 0.58
White Matter5.15 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Egfl7CBCerebellum8.7
13.47
Egfl7CTXCerebral cortex40.18
31.21
Egfl7HIPHippocampal region26.02
28.1
Egfl7HPFHippocampal formation25.09
26.1
Egfl7HYHypothalamus9.16
9.26
Egfl7LSXLateral septal complex19.07
24.21
Egfl7MBMidbrain11.16
13.56
Egfl7MYMedulla6.65
11.33
Egfl7OLFOlfactory bulb21.7
17.05
Egfl7PPons8.6
13.18
Egfl7PALPallidum18.81
17.04
Egfl7RHPRetrohippocampal region23.67
22.94
Egfl7sAMYStriatum-like amygdalar nuclei19.94
16.06
Egfl7STRStriatum19.35
14.18
Egfl7STRdStriatum dorsal region19.39
14.29
Egfl7STRvStriatum ventral region17.85
11.39
Egfl7THThalamus16.21
15.27
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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