Annotation Detail for DCTN4
Basic Information Top
| Gene Symbol: | DCTN4 ( - ) |
|---|---|
| Gene Full Name: | dynactin 4 (p62) |
| Band: | 5q33.1 |
| Quick Links | Entrez ID:51164; OMIM: NA; Uniprot ID:DCTN4_HUMAN; ENSEMBL ID: ENSG00000132912; HGNC ID: 15518 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.675564
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 10 / 70761 | 141 |  |
| blastocyst | 5 / 62319 | 80 | |
| fetus | 66 / 564012 | 117 | |
| neonate | 5 / 31097 | 160 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 7 / 55556 | 125 | |
| adult | 111 / 1939121 | 57 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 |  |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 1 / 114246 | 8 |  |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 7 / 119369 | 58 | |
| germ cell tumor | 28 / 263845 | 106 | |
| glioma | 16 / 106883 | 149 | |
| head and neck tumor | 31 / 136302 | 227 |  |
| kidney tumor | 6 / 68959 | 87 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 6 / 96359 | 62 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 11 / 97250 | 113 | |
| normal | 444 / 3360307 | 132 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 8 / 104616 | 76 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 6 / 102680 | 58 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 8 / 124949 | 64 | |
| soft tissue/muscle tissue tumor | 8 / 125191 | 63 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 3 / 13106 | 228 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 0 / 29757 | 0 | |
| blood | 5 / 123478 | 40 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 6 / 48801 | 122 | |
| brain | 311 / 1100989 | 282 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 19 / 149255 | 127 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 22 / 215722 | 101 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 13 / 211054 | 61 | |
| heart | 3 / 89626 | 33 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 16 / 211777 | 75 | |
| larynx | 1 / 24145 | 41 | |
| liver | 11 / 207743 | 52 | |
| lung | 33 / 336974 | 97 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 5 / 91610 | 54 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 24 / 67052 | 357 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 3 / 15768 | 190 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 14 / 214812 | 65 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 2 / 16585 | 120 | |
| placenta | 26 / 280825 | 92 | |
| prostate | 9 / 189345 | 47 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 13 / 210574 | 61 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 4 / 96619 | 41 | |
| testis | 86 / 330442 | 260 | |
| thymus | 4 / 81131 | 49 | |
| thyroid | 8 / 47473 | 168 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 19 / 52413 | 362 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 24 / 232878 | 103 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 218013_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 11.6 | |
| Adipocyte | 15.9 | |
| AdrenalCortex | 4.4 | |
| Adrenalgland | 3.55 | |
| Amygdala | 6.65 | |
| Appendix | 4.4 | |
| AtrioventricularNode | 3.45 | |
| BDCA4+_DentriticCells | 5.45 | |
| Bonemarrow | 4.15 | |
| BronchialEpithelialCells | 5.2 | |
| CD105+_Endothelial | 5.75 | |
| CD14+_Monocytes | 4.85 | |
| CD19+_BCells(neg._sel.) | 4.5 | |
| CD33+_Myeloid | 8.1 | |
| CD34+ | 6.5 | |
| CD4+_Tcells | 4.65 | |
| CD56+_NKCells | 5 | |
| CD71+_EarlyErythroid | 19.95 | |
| CD8+_Tcells | 7.1 | |
| CardiacMyocytes | 5.8 | |
| Caudatenucleus | 3.85 | |
| Cerebellum | 3.55 | |
| CerebellumPeduncles | 4.9 | |
| CiliaryGanglion | 3.55 | |
| CingulateCortex | 4.3 | |
| Colorectaladenocarcinoma | 4.15 | |
| DorsalRootGanglion | 3.35 | |
| FetalThyroid | 5.45 | |
| Fetalbrain | 10.35 | |
| Fetalliver | 4.9 | |
| Fetallung | 3.75 | |
| GlobusPallidus | 3.25 | |
| Heart | 5.15 | |
| Hypothalamus | 4.5 | |
| Kidney | 3.3 | |
| Leukemia_chronicMyelogenousK-562 | 5 | |
| Leukemia_promyelocytic-HL-60 | 3.8 | |
| Leukemialymphoblastic(MOLT-4) | 3.3 | |
| Liver | 5.55 | |
| Lung | 4.5 | |
| Lymphnode | 3.45 | |
| Lymphoma_burkitts(Daudi) | 5.3 | |
| Lymphoma_burkitts(Raji) | 5.8 | |
| MedullaOblongata | 3.9 | |
| OccipitalLobe | 4.25 | |
| OlfactoryBulb | 3.25 | |
| Ovary | 2.9 | |
| Pancreas | 3.35 | |
| PancreaticIslet | 5.7 | |
| ParietalLobe | 4.65 | |
| Pituitary | 11.5 | |
| Placenta | 10.25 | |
| Pons | 4.7 | |
| PrefrontalCortex | 7.7 | |
| Prostate | 4.9 | |
| Salivarygland | 4.15 | |
| SkeletalMuscle | 4.9 | |
| Skin | 3.4 | |
| SmoothMuscle | 5.8 | |
| Spinalcord | 4.65 | |
| SubthalamicNucleus | 4 | |
| SuperiorCervicalGanglion | 4.95 | |
| TemporalLobe | 4.85 | |
| Testis | 3.65 | |
| TestisGermCell | 4.5 | |
| TestisIntersitial | 4.1 | |
| TestisLeydigCell | 4.15 | |
| TestisSeminiferousTubule | 3.8 | |
| Thalamus | 4.45 | |
| Thymus | 3.35 | |
| Thyroid | 5.2 | |
| Tongue | 4.3 | |
| Tonsil | 4.05 | |
| Trachea | 3.5 | |
| TrigeminalGanglion | 4.3 | |
| Uterus | 4.5 | |
| UterusCorpus | 3.65 | |
| WholeBlood | 4.9 | |
| Wholebrain | 4.8 | |
| colon | 4.5 | |
| pineal_day | 24.28 | |
| pineal_night | 20.9 | |
| retina | 5.375 | |
| small_intestine | 6.05 | |
- Probe name: CUST_7476_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.18 ± 0.44 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.12 ± 0.19 | |
| Basal Part of Pons | 5.07 ± 0.34 | |
| Cerebellar Cortex | 5.33 ± 0.31 | |
| Cerebellar Nuclei | 4.94 ± 0.38 | |
| Claustrum | 4.96 ± 0.71 | |
| Epithalamus | 5.23 ± 0.44 | |
| Frontal Lobe | 4.99 ± 0.44 | |
| Globus Pallidus | 5.24 ± 0.32 | |
| Hypothalamus | 4.89 ± 0.5 | |
| Insula | 4.98 ± 0.41 | |
| Limbic Lobe | 5.21 ± 0.33 | |
| Mesencephalon | 5.15 ± 0.39 | |
| Myelencephalon | 5.09 ± 0.42 | |
| Occipital Lobe | 5.49 ± 0.38 | |
| Parietal Lobe | 5.12 ± 0.32 | |
| Pontine Tegmentum | 5.12 ± 0.42 | |
| Striatum | 5.03 ± 0.33 | |
| Subthalamus | 4.85 ± 0.6 | |
| Temporal Lobe | 5.09 ± 0.32 | |
| Thalamus | 5.15 ± 0.42 | |
| White Matter | 5.86 ± 0.32 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Dctn4 | CB | Cerebellum | 15.35 | |
| 22.55 | | |||
| Dctn4 | CTX | Cerebral cortex | 48.97 | |
| 42.6 | | |||
| Dctn4 | HIP | Hippocampal region | 37.16 | |
| 64.22 | | |||
| Dctn4 | HPF | Hippocampal formation | 38.93 | |
| 52.74 | | |||
| Dctn4 | HY | Hypothalamus | 31.06 | |
| 28.48 | | |||
| Dctn4 | LSX | Lateral septal complex | 0 | |
| 0 | | |||
| Dctn4 | MB | Midbrain | 37.12 | |
| 35.45 | | |||
| Dctn4 | MY | Medulla | 19.94 | |
| 27.25 | | |||
| Dctn4 | OLF | Olfactory bulb | 34.33 | |
| 30.61 | | |||
| Dctn4 | P | Pons | 21.7 | |
| 27.74 | | |||
| Dctn4 | PAL | Pallidum | 16.83 | |
| 17.12 | | |||
| Dctn4 | RHP | Retrohippocampal region | 42.52 | |
| 41.04 | | |||
| Dctn4 | sAMY | Striatum-like amygdalar nuclei | 10.79 | |
| 8.58 | | |||
| Dctn4 | STR | Striatum | 11.85 | |
| 9.63 | | |||
| Dctn4 | STRd | Striatum dorsal region | 10.4 | |
| 8.78 | | |||
| Dctn4 | STRv | Striatum ventral region | 17.86 | |
| 12.62 | | |||
| Dctn4 | TH | Thalamus | 26.2 | |
| 25.27 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| DCTN4_HUMAN_2 | 8 | 2 | 9 | ASLLQSDR | PRIDE |
| PAp00000632 | 10 | 22 | 31 | APLSQLYFCR | Peptide Atlas |